Current Topics in Membranes and Transport
Cellular and Molecular Biology of Sodium Transport
Academic Press
Published on 4. October 1989
378 pages
978-0-08-058505-5 (ISBN)
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Current Topics in Membranes and Transport
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Felix Bronner | A. Kleinzeller
Current Topics in Membranes and Transport: Cellular and Molecular Biology of Sodium Transport v. 34
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08/1989
Academic Press
€119.47
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Content
- Front Cover
- Cellular and Molecular Biology of Sodium Transport
- Copyright Page
- Contents
- Preface
- Yale Membrane Transport Processes Volumes
- Chapter 1. Physical State of Cell Sodium
- I. Introduction
- II. Relationship of Average Concentration to Cytosolic Activity of Cell Sodium Ions
- III. Summary
- References
- Chapter 2. lntracellular Sodium Activities and Basolateral Membrane Potassium Conductances of Sodium-Absorbing Epithelial Cells
- I. Introduction
- II. Chronic Stimulation of Sodium Absorption by Hyperaldosteronism
- III. Rapid Stimulation of Transcellular Sodium Absorption
- IV. Conclusions and Speculations
- V. Summary
- References
- Chapter 3. Feedback Regulation of Epithelial Sodium Channels
- I. Introduction
- II. Observations of Feedback Control
- III. Possible Mediators of Feedback Control
- IV. Conclusions
- References
- Chapter 4. Electron Microprobe Analysis of Cell Sodium in Epithelia
- I. Electron Microprobe Analysis
- II. State and Distribution of Intracellular Ions
- III. Analysis of Epithelial Ion Transport
- References
- Chapter 5. Sodium Dependence of Cation Permeabilities and Transport
- I. Introduction
- II. Evidence for Membrane Transport Regulation
- III. Examples of Membrane Transport Regulation: Cross-Talk
- IV. Possible Signal for Regulation of Membrane Properties
- V. Transport and Cell Volume
- VI. Regulatory Mechanisms of Channels and Transporters
- VII. Possible Cellular Transducers
- VIII. Reassessment of Double-Membrane Model
- IX. Uncharted Regions
- X. Summary
- References
- Chapter 6. The "Second" Sodium Pump and Cell Volume
- I. Introduction
- II. Sodium Transport in Kidney Slices
- III. Sodium-Stimulated ATPase Activities
- IV. Active Sodium Uptake in Basolateral Plasma Membrane Vesicles
- V. Cellular Volume and ATPase Activity
- VI. Conclusions
- References
- Chapter 7. Rapid Stimulation-Associated Changes in Exocrine Na+,K+ -ATPase Subcellular Distribution
- I. Introduction
- II. Role of Na+,K+ -ATPase in Sodium Chloride Secretion
- III. Functional and Immunocytochemical Evidence for Cytoplasmic Na+,K+ -ATPase Pools
- IV. Delineation of Cytoplasmic Na+,K+ -ATPase Pools
- V. Stimulation-Associated Recruitment of Na+,K+-ATPase to Lacrimal Acinar Cell Basolateral Plasma Membranes
- References
- Chapter 8. Differential Subunit and lsoform Expression Involved in Regulation of Sodium Pump in Skeletal Muscle
- I. Introduction
- II. Isoforms of Avian Sodium Pump a and ß Subunits
- III. Analysis of Subunit Function and Regulation through Expression of Avian Sodium Pump cDNAs in Tissue-Cultured Mouse Cells
- IV. Veratridine-Induced Up-Regulation of Sodium Pump in Primary Muscle Cultures
- V. Regulation of Sodium Pump in Other Systems
- References
- Chapter 9. Transepithelial Sodium Transport and Its Control by Aldosterone: A Molecular Approach
- I. Introduction
- II. Mechanism of Action of Aldosterone: A Model
- III. Control of Sodium Transport by Aldosterone in Vitro
- IV. Strategy for Cloning Sodium Pump and Sodium Channel Using Antibody Recognizing a Shared Epitope
- V. Role of Sodium Channel in Early Mineralocorticoid Response
- VI. Role of Na+,K+ -ATPase in Late Mineralocorticoid Response
- VII. Conclusions
- References
- Chapter 10. Involvement of Na+,K+ -ATPase in Antinatriuretic Action of Mineralocorticoids in Mammalian Kidney
- I. Introduction
- II. Localization of Aldosterone Receptors along the Nephron
- III. Aldosterone Control of Na+,K+ -ATPase Activity in Specific Nephron Segments
- IV. Methodology for Studying Mechanism of Aldosterone Action on Tbbular Na+,K + -ATPase
- V. Mechanism of Aldosterone Action on Na+ ,K+-ATPase in the Collecting Tubule
- References
- Chapter 11. Modulation of Na+,K+ -ATPase Expression in Renal Collecting Duct
- I. Introduction
- II. Cellular Model for Sodium and Potassium Transport in Cortical Collecting Duct
- III. Cellular Actions of Aldosterone
- IV. Modulation of Aldosterone Actions
- V. Cell Volume Changes as Part of Aldosterone Actions
- Vl. Summary
- References
- Chapter 12. Electrogenic Properties of the Na/K Pump: Voltage Dependence and Kinetics of Charge Translocation
- I. Introduction
- II. Fast Charge Translocations Associated with Partial Reactions of the Na/K Pump
- III. Voltage Dependence of Transport Rates
- IV. Conclusion
- References
- Chapter 13. Sodium Pump Current in Renal Tubular Cells
- I. Introduction
- II. Methods Used to Study Pump Current in Epithelial Cells
- Ill. Pump Current in Collecting Tubule of Amphiuma
- IV. Conclusion
- References
- Chapter 14. Voltage Dependence of Na/K Pump Current
- I. Introduction
- II. Experimental Approach
- III. Steady-State Na/K Pump Current Is Strongly Voltage Dependent
- IV. Voltage Dependence of Outward Na/K Pump Current Is Attenuated at Low [Na]o
- V. Transient Pump Currents Are Associated with Sodium Translocation
- VI. Voltage-Sensitive Steps
- VII. Rate-Limiting Steps
- References
- Chapter 15. Sodium-Calcium Exchange in Cardiac, Smooth, and Skeletal Muscles: Key to Control of Contractility
- I. Introduction
- II. Na+-Ca2+ Exchange in Barnacle Muscle
- III. Na+-Ca2+ Exchange in Vertebrate Skeletal Muscle
- IV. Na+-Ca2+ Exchange in Cardiac Muscle
- V. Na+-Ca2+ Exchange in Smooth Muscles
- VI. Conclusion
- References
- Chapter 16. Activation of Sodium-Hydrogen Exchange by Mitogens
- I. Introduction
- II. Activation of Antiport by Mitogens and Comitogens
- III. Na+-H+ Exchange and Initiation of Proliferation
- IV. Na+-H+ Exchange and Increased Protooncogene RNA Levels
- V. Concluding Remarks
- References
- Chapter 17. Sodium Pump Regulation by Endogenous Inhibitors
- I. Background
- II. Hypothalamic Na+ ,K+-ATPase Inhibitor
- III. Discussion
- References
- Index
