
Current Topics in Developmental Biology
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Content
- Front Cover
- Current Topics in Developmental Biology
- Copyright Page
- Contents
- Alberto Monroy 1913-1986
- Preface
- Chapter 1. Mammalian Development Futures,1987
- I. Introduction
- II. Cell lineages
- Ill. Developmental Genetics
- IV. Gene Expression
- References
- Chapter 2. Cytoskeletal Alterations And Nuclear Architertural Changes During Mammalian Fertilization
- I. Introduction
- II. The Question of Actin Polymerization during the Acrosome Reaction
- III. Absence of a Requirement for Microfilament Assembly during Sperm Incorporation
- IV. Cytoskeletal Dynamics in the Unfertilized Oocyte
- V. Mechanisms Accounting for Pronuclear Migrations
- VI. Pronuclear Development and Nuclear Architecture
- VII. Centrosomes during Mammalian Fertilization
- VIII. Conclusions
- References
- Chapter 3. Developmental Potency Of Gametic And Embryonic Genomes Revealed By Nuclear Transfer
- I. Introduction
- II. Role of Maternal and Paternal Genomes in Mammalian Development
- III. Stability or Reprogramming of the Embryonic Genome
- IV. Conclusions and Perspectives
- References
- Chapter 4. Ovum Factor And Early Pregnancy Factor
- I. Introduction
- II. Assay for EPF: The Rosette Inhibition Test
- III. EPF in Preimplantation Pregnancy Serum
- IV. Serum EPF after Embryo Transfer
- V. Serum EPF after Induced Abortion
- VI. EPF Production: Tissues of Source
- VII. Ovum Factor: Embryonic Signal for EPF Production
- VIII. Cooperation of Prolactin with Ovum Factor in EPF Release from the Ovary
- IX. Passive Immunization of Pregnant Mice with Monoclonal Antibodies to EPF
- X. Role of EPF in Pregnancy
- XI. Conclusions
- References
- Chapter 5. Development of The Human Preimplanition Embryo In Vitro
- I. Introduction
- II. The Source of Human Embryos for Research
- III. Factors Influencing the Success of Human Embryogenesis in Vitro
- IV. Conclusions
- References
- Chapter 6. Cell Lineage Analysis in Mammalian Embryogenesis
- I. Introduction
- II. Techniques for Lineage Analysis in Mammalian Embryos
- III. Lineage Analysis: Experimental Results
- IV. Conclusions and Perspectives
- Note Added in Proof
- References
- Chapter 7. Cellular Interactions of Mouse Fetal Germ Cells in in Vitro Systems
- I. Introduction
- II. Germ Cell Differentiation in the Mouse Embryo
- III. Cellular Interactions during Early Germ Cell Differentiation
- IV. Concluding Remarks
- References
- Chapter 8. Testis Determination and the H-Y Hypothesis
- I. Introduction
- II. Testis Formation
- Ill. Sex Commitment
- IV. Is There a "Male-Determining" Substance?
- V. Male-Specific Antigen
- VI. The H-Y Hypothesis
- VII. IS SDM Antigen a "Male-Determining" Factor in Mammals?
- VIII. Is H-Y Antigen a "Male-Determining" Factor in Mammals?
- IX. Genes on the Y Chromosome
- X. Conclusions
- Note Added in Proof
- References
- Chapter 9. Cell Heterrogeneity In The Myogenic Lineage
- I. Introduction
- II. One or More Myogenic lineages?
- Ill. Somites and Early Differentiation
- IV. Limb Colonization and limb Cell Heterogeneity
- V. The Emergence and Differentiation of Satellite Cells
- VI. How Many Different Precursor Muscle Cells?
- VII. Muscle Cell Heterogeneity and Primary Myopathies
- VIII. Conclusions and Future Perspectives
- References
- Chapter 10. Immunological Aspects Of Implantation And Fetal Survival:The Central Role Of Trophoblast
- I. Introduction
- II. MHC Antigen Expression on the Developing Embryo
- III. Trophoblast Susceptibility to Immune Attack
- IV. Pregnancy-induced Maternal immune Responses
- V. Immunogenic Stimulus in Pregnancy
- VI. lmmunoregulatory Mechanisms for Maternal Responses
- VII. Are lmmunoregulatory Factors Essential for SuccessfuI Pregnancy?
- VIII. The Maternofetal Interface: Other Aspects
- IX. Relevance of Nonhistocompatibility Antigen Systems
- X. Immunological Aspects of Pregnancy Failure
- XI. Concluding Remarks
- References
- Chapter 11. Homeo Box Genes In Murine Developement
- I. Introduction
- II. The Genetics of Homeosis in Drosophila and the Homeo Box
- III. Murine Homeo Box Gene Organization
- IV. Homeo Box Gene Expression
- V. The Homeo Box as a DNA-Bi nd i ng Doma in
- VI. Homeosis and Mammalian Development
- VII. Summary
- References
- Index
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