Current Topics in Developmental Biology
Academic Press
Published on 27. May 1980
341 pages
978-0-08-058436-2 (ISBN)
Description
Current Topics in Developmental Biology
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Aron A. Moscona | Martin Friedlander
Current Topics in Developmental Biology: v. 13
Book
12/1979
Academic Press
€69.44
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Content
- Front Cover
- Immunological Approaches to Embryonic Development and Differentiation
- Copyright Page
- CONTENTS
- List of Contributors
- Preface
- Conspectus
- Chapter 1. Cell Surface Antigens during Mammalian Spermatogenesis
- I. Introduction
- II. Isolation of Mammalian Seminiferous Cells
- III. Temporal Appearance of Surface Antigens during Spermatogenesis
- IV. Membrane Mobility of Spermatogenic Cells
- V. Selective Partitioning of Membrane Antigens during Spermiogenesis
- VI. Isolation of Germ Cell Plasma Membranes
- VII. Concluding Remarks
- References
- Chapter 2. lmmunoperoxidase Localization of Bindin during the Adhesion of Sperm to Sea Urchin Eggs
- I. Introduction
- II. Preparation of Antigen and Antisera
- III. Characterization of Antibindin by Immunodiffusion Assay
- IV. Ultrastructural Immunohistochemical Localization of Bindin
- V. Concluding Remarks
- References
- Chapter 3. Cell Surface Differentiations during Early Embryonic Development
- I. Introduction
- II. The Problem of Polarity
- III. The Segregation of Cell Lines
- IV. The Sperm-Egg Interaction in Fertilization
- V. Concluding Remarks
- References
- Chapter 4. Immunofluorescent Analysis of Chromatin Structure in Relation to Gene Activity: A Speculative Essay
- I. Introduction
- II. The Technique of Immunofluorescence Antibody Staining
- III. Patterns of Chromosomal Protein Distribution in Relation to Gene Activity
- IV. Concluding Remarks
- References
- Chapter 5. lmmunogenetics of Mammalian Cell Surface Macromolecules
- I. Introduction
- II. Human-Chinese Hamster Ovary Cell Hybrids
- III. Immunologic Specificity of Human and Chinese Hamster Ovary Cell Surface Structures
- IV. Human Antigens (AL, BL., CL, etc.) Expressed on Human-Chinese Hamster Somatic Cell Hybrids
- V. Analysis in Depth of the AL Antigenic System
- VI. Use of AL System to Detect Environmental Mutagens
- VII. Cell Surface Antigens of Wide and of Limited Distribution among Different Tissues
- VIII. Discussion
- IX. Concluding Remarks
- References
- Chapter 6. Cell Surface and Early Stages of Mouse Embryogenesis
- I. Introduction
- II. The Teratocarcinoma System
- III. Glycopeptides
- IV. Lectin Receptors
- V. Surface Antigens
- VI. Surface Structures and Cellular Interactions in Early Development
- VII. Concluding Remarks
- References
- Chapter 7. Developmental Stage-Specific Antigens during Mouse Embryogenesis
- I. Introduction
- II. Immunological Analysis of Stage-Specific Antigens
- III. Conclusions and Perspectives
- IV. Concluding Remarks
- References
- Chapter 8. Early Embryonic Cell Surface Antigens as Developmental Probes
- I. Introduction
- II. Cell Surface Antigens of Gametes and Preimplantation Embryos
- III. Future Studies on Embryonic Cell Surface Antigens as Developmental Probes
- IV. Concluding Remarks
- References
- Chapter 9. Surface Antigens Involved in Interactions of Embryonic Sea Urchin Cells
- I. Introduction
- II. Adhesive Specificity: Demonstrations of Recognition Capabilities
- III. Immunochemical Specificity: Changes Associated with Gastrulation
- IV. Relationship between Cell Surface Antigens and Cell-Cell Interactions
- V. Synthesis and Conclusions
- VI. Concluding Remarks
- References
- Chapter 10. Cell Surface Antigens of Cultured Neuronal Cells
- I. Introduction
- II. Neural-Specific Antigens of Cultured Neuronal Cells
- III. Do Mouse Neuroblastama Cells Differentiate in Vitro?
- IV. Approaches to Neural Cell-Cell Interaction
- V. Perspectives on Future Research Directions
- VI. Concluding Remarks
- References
- Chapter 11. Cell Type-Specific Antigens of Cells of the Central and Peripheral Nervous System
- I. Introduction
- II. Specific Antigens for Different Neural Cell Types
- III. Thy-1: A Developmental Antigen on Neuronal Cells
- IV. Present and Potential Applications of Antibodies
- V. Concluding Remarks
- References
- Chapter 12. Cell Surface Antigens of the Nervous System
- I. Introduction
- II. Cell Type-Specific Cell Surface Antigens
- III. Developmental Expression of Antigens
- IV. Subcellular Distribution of Antigens
- V. Concluding Remarks
- References
- Chapter 13. Antibody Effects on Membrane Antigen Expression
- I. Introduction
- II. Antigenic Modulation as a Model System for Studying Ligand-Induced Effects on Receptor Expression
- III. The Metabolism of TL Antigens in the Presence (and Absence) of TL Antiserum
- IV. Membrane Antigens of Somatic Hybrids of TL(+) and TL(-) Cells
- V. Failure of TL Antigens of Hybrid Cells to Undergo Modulation
- VI. Metabolism of Membrane Antigens of Hybrid Cells
- VII. The Quantities of TL Antigens of Parental and Hybrid Cells
- VIII. Discussion
- IX. Similar Features of Down Regulation and Antigenic Modulation
- X. Concluding Remarks
- References
- Chapter 14. Topographic Display of Cell Surface Components and Their Role in Transmembrane Signaling
- I. Introduction
- II. Plasma Membrane Organization
- III. Dynamics of Cell Membrane Components
- IV. Topographic Control of Cell Surface Receptors
- V. Transmembrane-Mediated Communication
- VI. Concluding Remarks
- References
- Subject Index
- Contents of Previous Volumes
