Target Organ Toxicity
Volume 2
1st Edition
Published on 28. April 2020
234 pages
978-1-000-69738-4 (ISBN)
Description
First published in 1986: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.
More details
Series
Edition
1. Auflage
Language
English
Place of publication
London
United Kingdom
Publishing group
Taylor & Francis Ltd
Target group
Professional and scholarly
Product notice
Reflowable
ISBN-13
978-1-000-69738-4 (9781000697384)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Book
12/2022
1st Edition
CRC Press
€61.84
The article will not be published
Book
06/2020
1st Edition
CRC Press
€222.84
Shipment within 15-20 days
Person
Gerald M. Cohen Ph.D. is Head of the Toxicology Unit, Department of Pharmacology, The School of Pharmacy, University of London.
Content
1. The Kidney as a Target Organ for Toxicity 2. Cardiac Toxicity 3. The Lung as a Target Organ for Toxicity 4. Target Organ Toxicity: The Male Reproductive System 5. Toxic Effects on the Female Reproductive System 6. The Eye 7. The Inner Ear 8. The Endocrine Pancreas as a Target Organ for Toxicity 9. Structural DNA Modifications and DNA Repair in Organ-Specific Tumor Induction 10. Organ Specificity in Tumor Initiation and Comple Carcinogenesis (Including Species Variation)
