
Advanced Methods and Tools for ECG Data Analysis
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Content
- Advanced Methods and Tools for ECG Data Analysis
- Contents v
- Preface xi
- Chapter 1 The Physiological Basis of the Electrocardiogram 1
- 1.1 Cellular Processes That Underlie the ECG 1
- 1.2 The Physical Basis of Electrocardiography 4
- 1.3 Introduction to Clinical Electrocardiography: Abnormal Patterns 12
- 1.4 Summary 24
- References 24
- Selected Bibliography 25
- Chapter 2 ECG Acquisition, Storage, Transmission, and Representation 27
- 2.1 Introduction 27
- 2.2 Initial Design Considerations 28
- 2.3 Choice of Data Libraries 35
- 2.4 Database Analysis--An Example Using WFDB 37
- 2.5 ECG Acquisition Hardware 41
- 2.6 Summary 50
- References 50
- Chapter 3 ECG Statistics, Noise, Artifacts, and Missing Data 55
- 3.1 Introduction 55
- 3.2 Spectral and Cross-Spectral Analysis of the ECG 55
- 3.3 Standard Clinical ECG Features 60
- 3.4 Nonstationarities in the ECG 64
- 3.5 Arrhythmia Detection 67
- 3.6 Noise and Artifact in the ECG 69
- 3.7 Heart Rate Variability 71
- 3.8 Dealing with Nonstationarities 83
- 3.9 Summary 92
- References 93
- Chapter 4 Models for ECG and RR Interval Processes 101
- 4.1 Introduction 101
- 4.2 RR Interval Models 102
- 4.3 ECG Models 115
- 4.4 Conclusion 126
- References 127
- Chapter 5 Linear Filtering Methods 135
- 5.1 Introduction 135
- 5.2 Wiener Filtering 136
- 5.3 Wavelet Filtering 140
- 5.4 Data-Determined Basis Functions 148
- 5.5 Summary and Conclusions 167
- References 167
- Chapter 6 Nonlinear Filtering Techniques 171
- 6.1 Introduction 171
- 6.2 Nonlinear Signal Processing 172
- 6.3 Evaluation Metrics 178
- 6.4 Empirical Nonlinear Filtering 179
- 6.5 Model-Based Filtering 186
- 6.6 Conclusion 193
- References 194
- Chapter 7 The Pathophysiology Guided Assessment of T-Wave Alternans 197
- 7.1 Introduction 197
- 7.2 Phenomenology of T-Wave Alternans 197
- 7.3 Pathophysiology of T-Wave Alternans 197
- 7.4 Measurable Indices of ECG T-Wave Alternans 199
- 7.5 Measurement Techniques 201
- 7.6 Tailoring Analysis of TWA to Its Pathophysiology 207
- 7.7 Conclusions 211
- Acknowledgments 211
- References 211
- Chapter 8 ECG-Derived Respiratory Frequency Estimation 215
- 8.1 Introduction 215
- 8.2 EDR Algorithms Based on Beat Morphology 218
- 8.3 EDR Algorithms Based on HR Information 228
- 8.4 EDR Algorithms Based on Both Beat Morphology and HR 229
- 8.5 Estimation of the Respiratory Frequency 230
- 8.6 Evaluation 236
- 8.7 Conclusions 240
- References 241
- Appendix 8A Vectorcardiogram Synthesis from the 12-Lead ECG 243
- Chapter 9 Introduction to Feature Extraction 245
- 9.1 Overview of Feature Extraction Phases 245
- 9.2 Preprocessing 248
- 9.3 Derivation of Diagnostic and Morphologic Feature Vectors 251
- 9.4 Shape Representation in Terms of Feature-Vector Time Series 260
- References 263
- Appendix 9A Description of the Karhunen-Lo`eve Transform 264
- Chapter 10 ST Analysis 269
- 10.1 ST Segment Analysis: Perspectives and Goals 269
- 10.2 Overview of ST Segment Analysis Approaches 270
- 10.3 Detection of Transient ST Change Episodes 272
- 10.4 Performance Evaluation of ST Analyzers 278
- References 287
- Chapter 11 Probabilistic Approaches to ECG Segmentation and Feature Extraction 291
- 11.1 Introduction 291
- 11.2 The Electrocardiogram 292
- 11.3 Automated ECG Interval Analysis 293
- 11.4 The Probabilistic Modeling Approach 294
- 11.5 Data Collection 296
- 11.6 Introduction to Hidden Markov Modeling 296
- 11.7 Hidden Markov Models for ECG Segmentation 304
- 11.8 Wavelet Encoding of the ECG 311
- 11.9 Duration Modeling for Robust Segmentations 312
- 11.10 Conclusions 316
- References 316
- Chapter 12 Supervised Learning Methods for ECG Classification/Neural Networks and SVM Approaches 319
- 12.1 Introduction 319
- 12.2 Generation of Features 320
- 12.3 Supervised Neural Classifiers 324
- 12.4 Integration of Multiple Classifiers 330
- 12.5 Results of Numerical Experiments 331
- 12.6 Conclusions 336
- Acknowledgments 336
- References 336
- Chapter 13 An Introduction to Unsupervised Learning for ECG Classification 339
- 13.1 Introduction 339
- 13.2 Basic Concepts and Methodologies 339
- 13.3 Unsupervised Learning Techniques and Their Applications in ECG Classification 341
- 13.4 GSOM-Based Approaches to ECG Cluster Discovery and Visualization 352
- 13.5 Final Remarks 359
- References 362
- About the Authors 367
- Index 371
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