Genetic Toxicology and Cancer Risk Assessment
1st Edition
Published on 31. August 2001
406 pages
978-1-135-55420-0 (ISBN)
Description
Presents state-of-the-art regulatory cancer risk assessment models including a biologically based model for two-hit carcinogenesis and cell proliferation!
This book comprehensively reviews the various roles of genetic toxicology in human cancer risk assessment conducted by United States and worldwide regulatory agencies-discussing hazard identification, dose-response relationships, exposure assessment, and current practices of risk characterization.
Examines predictive values of mutagenicity tests, mechanisms of carcinogenesis, and conventional genotoxicity tests required by the International Conference on Harmonization and the Organization for Economic Cooperation and Development/Environmental Protection Agency guidelines!
This book comprehensively reviews the various roles of genetic toxicology in human cancer risk assessment conducted by United States and worldwide regulatory agencies-discussing hazard identification, dose-response relationships, exposure assessment, and current practices of risk characterization.
Examines predictive values of mutagenicity tests, mechanisms of carcinogenesis, and conventional genotoxicity tests required by the International Conference on Harmonization and the Organization for Economic Cooperation and Development/Environmental Protection Agency guidelines!
Reviews / Votes
"...engaging and informative....
...a useful contribution to the field of genetic toxicology.
"-Doody
"...well-detailed....
...a great reference material.
"-Australian Journal of Medical Science
"...offers the reader an authoritative, practical insight.
"-Cancer Forum
More details
Edition
1. Auflage
Language
English
Place of publication
London
United Kingdom
Publishing group
Taylor & Francis Ltd
Target group
Professional and scholarly
Product notice
Reflowable
ISBN-13
978-1-135-55420-0 (9781135554200)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Wai Nang Choy
Genetic Toxicology and Cancer Risk Assessment
Book
08/2001
1st Edition
CRC Press
€273.30
Article not available at the moment
Book
08/2001
Marcel Dekker Inc
€141.13
Shipment within 15-20 days
Person
Wai Nang Choy
Content
Human Cancer Genetics Jason W. Barlow and David Malkin Genetic Toxicity Tests for Predicting Carcinogenicity Errol Zeiger Genotoxic and Nongenotoxic Mechanisms of Carcinogenesis Wai Nang Choy Structure-Activity Relationship (SAR) and its Roles in Cancer Risk Assessment David Y. Lai and Yin-tak Woo Regulatory Genetic Toxicology Tests Wai Nang Choy Complementary Genetic Toxicology Assays B. Bhaskar Gollapudi The Mouse Lymphoma Assay (MLA) Using the Microwell Method Masamitsu Honma and Toshio Sofuni The In Vitro Micronucleus Assay Marilyn J. Aardema and Micheline Kirsch-Volders ICH Guidelines on Genotoxicity and Carcinogenicity: Scientific Background and Regulatory Practice Lutz Mueller, Peter Kasper, and Leonard Schechtman New OECD Genetic Toxicology Guidelines and Interpretation of Results Michael C. Cimino Dose-Response Relationships in Chemical Carcinogenesis and Cancer Risk Assessment Werner K. Lutz Molecular Epidemiology and Biomarkers Jia-Sheng Wang, Jonathan M. Links, John Groopman Quantitative Cancer Risk Assessment of Nongenotoxic Carcinogens Anna M. Fan and Robert A. Howd Risk Assessment of Genotoxic Carcinogens Lauren Zeise Biologically Based Cancer Risk Assessment Models Suresh H. Moolgavkar
