Calcium and Cell Function

ContributorsPrefaceContents of Previous VolumeChapter 1 Calcium Binding to Proteins and Other Large Biological Anion Centers I. Introduction II. Extracellular Calcium-Binding Proteins III. Calcium Ion Binding to Large Particles, Membranes, and Surfaces IV. Calcium Transport V. Vesicles: Calcium Stores VI. Intracellular Proteins VII. Calcium-Binding Intestinal Proteins VIII. Calcium Proteins in Membranes IX. Summary: Intracellular Calcium References Chapter 2 Mitochondrial Regulation of Intracellular Calcium I. Introduction and Scope II. Mechanisms, Kinetics, and Regulation of Mitochondrial Ca2+ Transport III. Evidence for Mitochondrial Regulation of Cellular Ca2+ IV. Steady-State Buffering of Free Ca2+ by Mitochondria References Chapter 3 Calcium Movement and Regulation in Presynaptic Nerve Terminals I. Introduction II. Calcium Content and Intraterminal Ca2+ Distribution III. Ca2+ Entry Mechanisms IV. Ca2+ Efflux from Nerve Terminals V. C2+ Movements and Transmitter Release VI. Summary References Chapter 4 Calmodulin and Calcium-Binding Proteins: Evolutionary Diversification of Structure and Function I. Introduction II. Calcium Ions as Second Messengers III. The Evolution of the Ca2+ -Binding Protein Family IV. Parvalbumin as the Prototype of Suppressor Molecules V. Calmodulin as the Prototype of Sensor Molecules VI. Sequential Activation-Deactivation of Ca2+-Dependent Enzymes VII. Conclusion References Chapter 5 Troponin I. Introduction II. Ca2+-Binding to Troponin and the Regulation of Muscle Contraction III. Thin-Filament Protein Interactions in the Regulation of Muscle Contraction IV. Structure and Ca2+-Induced Structural Changes in Troponin V. Propagation of the Ca2+-Induced Structural Changes in Troponin C to Thin-Filament Proteins VI. Rates of Ca2+-Exchange and Structural Changes in Troponin C VII. Rates of Ca2+-Exchange in Troponin VIII. Conclusion References Chapter 6 Vitamin D-Induced Calcium-Binding Proteins I. Introduction II. Species and Tissue Distribution III. Properties of Calcium-Binding Proteins IV. Cellular Localization of Calcium-Binding Proteins V. Physiological Factors Affecting CaBP VI. In Vitro Synthesis of CaBP VII. Embryonic Development VIII. CaBP and Calcium Reabsorption in the Kidney IX. Temporal Responses of CaBP to Acute Doses of l,25(OH)2D3 X. Discussion References Chapter 7 ¿-Carboxyglutamic Acid-Containing Ca2+-Binding Proteins I. Introduction II. ¿-Carboxyglutamic Acid-Containing Proteins of Blood Plasma III. ¿-Carboxyglutamic Acid-Containing Protein of Bone IV. Other ¿-Carboxyglutamic Acid-Containing Proteins V. Summary References Chapter 8 Parvalbumins and Other Soluble High-Affinity Calcium-Binding Proteins from Muscle I. Introduction II. Historical Review III. Distribution of Sarcoplasmic Calcium-Binding Proteins in the Animal Kingdom IV. Parvalbumins V. Sarcoplasmic Calcium-Binding Proteins from Invertebrates VI. Physiological Implications ReferencesChapter 9 Myosin Light Chain Kinase in Skinned Fibers I. Introduction II. Usefulness of Skinned Fibers as a Model for Contraction III. Evidence for a Light Chain Kinase-Phosphatase System in Skinned Fibers IV. Summary References Chapter 10 Possible Roles of Calmodulin in a Ciliated Protozoan Tetrahymena I. Introduction II. Properties of Tetrahymena Calmodulin III. Activation of Membrane-Bound Guanylate Cyclase of Tetrahymena IV. Search for New Functions of Calmodulin in Tetrahymena V. Concluding Remarks References Chapter 11 Calcium Control of Actin Network Structure I. Introduction II. Structure of the Cortical Cytoplasm III. Regulation of Actin Gel-Sol Transformation IV.