
Excited State Dynamics in DNA and RNA
Description
Alles über E-Books | Antworten auf Fragen rund um E-Books, Kopierschutz und Dateiformate finden Sie in unserem Info- & Hilfebereich.
More details
Other editions
Additional editions

Person
Content
1.1 Introduction of the significance of triplet excited state in nucleic acids
1.2 Triplet excited state studies in 1960-70s with low temperature spectroscopy
1.3 Breakthroughs of time-resolved spectroscopy techniques and progress of triplet excited state study of DNA/RNA in 1980-2000
1.4 Current Research frontiers (2000s-present)
1.5 Book Structure Overview
Chapter 2 Triplet excited state in canonical nucleobases and their derivatives
2.1 Study on the triplet excited states dynamics of canonical nucleobases by laser flash photolysis and femtosecond transient absorption spectroscopy
2.2 Study on Triplet Excited-State Dynamics of Thio- and Selenium-Substituted Nucleobases
2.3 Study on Triplet Excited State Dynamics of Nitrogen-substituted Nucleobases
Chapter 3 Decoding Triplet-State Dynamics in Epigenetically Modified DNA and RNA: Photophysical Mechanisms from Nucleobase Monomers to Duplex
3.1 Introduction
3.2 Formation of Triplet State in Epigenetically Modified Nucleobase Monomer
3.3 Uracil C5-modified Nucleobases
3.4 Adenine N6-Modified Nucleobases
3.5 Guanosine N7-Modified Nucleobases
3.6 Formation of Triplet State in Epigenetically Modified Dinucleotides and Single-stranded Oligomers
3.7 Formation of Triplet State in Epigenetically Modified DNA duplex
3.8 Conclusion
Chapter 4 Triplet-Mediated Photochemistry of Nucleic Acid Bases
4.1 Introduction
4.2 Photoaddition reactions
4.3 Photooxidation reactions
4.4 Photo-crosslinking reactions
4.5 Conclusions
Chapter 5 Drug-sensitized triplet states generation in DNA
5.1 Introduction
5.2 The triplet-triplet energy transfer process
5.3 The triplet energy of nucleobases
5.4 Structure and triplet excited state energies of the different nucleobases
5.5 Photoproducts arising from the nucleobase triplet excited state
5.6 Methodologies: Spectroscopic vs analytical techniques for detection of drug photosensitization of 3N*
5.7 Photosensitization of nucleobase triplet by drugs (or cosmetics)
5.8 Conclusion
Chapter 6 Triplet decay in canonical and noncanonical DNA/RNA nucleobases
6.1 Introduction
6.2 Low Triplet Yields in Natural DNA/RNA Nucleobases
6.3 Triplet State Decay in Thionucleobases
6.4 Theoretical and Computational Studies of Triplet Decay of Thionucleobases
6.5 Mechanisms of Chemical Modulation of Triplet Decay
6.6 Remaining Challenges and Future Directions
Chapter 7 Triplet state dynamics in DNA/RNA nucleobases and DNA by Ab initio static and surface-hopping dynamics simulations
7.1 Introduction
7.2 Adenine
7.3 Guanine
7.4 Uracil
7.5 Thymine
7.6 Cytosine
7.7 Non-natural nucleobases
7.8 Pyrimidine-pyrimidine dimer formation processes
7.9 Conclusions
Chapter 8 The photophysics and photochemistry of epigenetics and 'natural' non canonical bases: insights from quantum mechanical calculations.
8.1 Introduction
8.2 Epigenetic bases
8.3 Methylated purines
8.4 Concluding Remarks
List of Abbreviations
Preface
- UV
- ultraviolet
- CPDs
- cyclobutane pyrimidine dimers
Chapter 1
- ISC
- intersystem crossing
- CPD
- cyclobutane pyrimidine dimer
- UV
- ultraviolet
- VR
- vibrational relaxation
- IC
- internal conversion
- AMP
- adenosine monophosphate
- GMP
- guanosine monophosphate
- TMP
- thymidine monophosphate
- CMP
- cytidine monophosphate
- UMP
- uridine monophosphate
- TTET
- triplet-triplet energy transfer
- T-T
- triplet-triplet
- ket
- electron transfer rate constant
- TRIR
- time-resolved infrared
- FC
- Franck-Condon
- SOC
- spin-orbit coupling
Chapter 2
- ISC
- intersystem crossing
- A
- adenine
- G
- guanine
- C
- cytosine
- T
- thymine
- U
- uracil
- Thy
- thymine
- Thd
- thymidine
- TMP
- thymidine-5´-monophosphate
- Urd
- Uridine
- UMP
- uridine-5´-monophosphate
- MeCN
- acetonitrile
- TRIR
- time-resolved infrared
- EADS
- evolution-associated difference spectra
- dCyd
- 2´-deoxycytidine
- 5mdCyd
- 2´-deoxy-5-methylcytidine
- FC
- Franck-Condon
- TRTL
- time-resolved thermal lens
- 2-tUra
- 2-thiouracil
- 3-tThd
- 2-thiothymidine
- 2,4-dtThy
- 2,4-dithiothymine
- TRPES
- time-resolved photoelectron spectroscopy
- 4-tUra
- 4-thiouracil
- 2,4-dtUra
- 2,4-dithiouracil
- GS
- ground state
- 2-tCyt
- 2-thiocytosine
- PES
- potential energy surface
- 3-tCyd
- 2-thiocytidine
- 3O2
- triplet oxygen
- REMPI
- resonance-enhanced multiphoton ionization
- 5-Me-tGua
- 6-methylthioguanine
- 2,6-dtPur
- 2,6-dithiopurine
- 6-SeGua
- 6-selenoguanine
- 4-aCyt
- 5-azacytosine
- 5-aUra
- 6-azauracil
- 6-aThy
- 6-azathymine
- 7-aAde
- 7-azaadenine
- 8-aGua
- 8-azaguanine
- TRPD
- time-resolved phosphorescence detection
- 7-aThd
- 6-azathymidine
- 6-aUrd
- 6-azauridine
Chapter 3
- ISC
- intersystem crossing
- 5mC
- 5-methylcytosine
- 5hmC
- 5-hydroxymethylcytosine
- 5fC
- 5-formylcytosine
- 5caC
- 5-carboxycytosine
- 5FC
- 5-fluorocytosine
- 5ClC
- 5-chlorocytosine
- 5BrC
- 5-bromocytosine
- 5AC
- 5-azacytidine
- CIs
- conical intersections
- CT
- charge-transfer
- 5mCyd
- 5-methylcytidine
- 5mdCyd
- 5-2´-deoxy-5-methylcytidine
- PES
- Potential energy surface
- 5hmdCyd
- 2´-deoxy-5-hydroxymethylcytidine
- TA
- transient absorption
- 5fdCyd
- 2´-deoxy-5-formylcytidine
- 5cadCyd
- 2´-deoxy-5-carboxylcytidine
- ICT
- intramolecular charge transfer
- AC
- 5-azacytosine
- 5ACyd
- 5-azacytidine
- 5AdCyd
- 2´-deoxy-5-azacytidine
- 5fU
- 5-formyluraci
- N6-mA
- N6-methyladenine
- N6-hmA
- N6-hydroxymethyladenine
- N6-fA
- N6-formyladenine
- N6-mAdo
- N6-methyladenosine
- D2O
- deuterated aqueous
- LE
- local excited
- N6-hmAdo
- N6-hydroxymethyladenosine
- N6-fAdo
- 6-formyladenosine
- fs-TA
- femtosecond transient absorption
- ns-TA
- nanosecond transient absorption
- oop
- out-of-plane
- SOC
- spin-orbit coupling
- SOCT-ISC
- spin-orbit charge transfer ISC
- m7G
- N7-methylguanosine
- FUPC
- fluorescence up-conversion
- 5mC
- 5-methylcytosine
- C
- cytosine
- ESA
- excited state absorption
- 3Intra-CT
- intrastrand triplet CT state
- HPLC
- high-performance liquid chromatography
- PAGE
- polyacrylamide gel electrophoresis
Chapter 4
- CPDs
- cyclobutane pyrimidine dimers
- SPs
- spore photoproducts
- GSO3
- guanosine-6-sulfonate
- DPCs
- DNA-protein crosslinks
- TiO2
- titanium dioxide
- 6-TG
- 6-thioguanine
- AuNPs
- gold nanoparticles
- 1O2
- singlet oxygen
- RNA
- ribonucleic acid
- DNA
- deoxyribonucleic acid
- UV
- ultraviolet
- ISC
- intersystem crossing
- CI
- conical intersection
- IC
- internal conversion
- SP
- spore photoproduct
- SPL
- spore photoproduct lyase
- SACs
- single-atom catalysts
- PDT
- photodynamic therapy
- 7-MP
- 6-mercaptopurine
- 6-TG
- 6-thioguanine
- ROS
- reactive oxygen species
- GSO2
- guanosine-6-sulfinate
- G
- guanosine
- GSO
- guanine sulfenic acid
- MCSCF
- multiconfigurational self-consistent field
- TD-DFT
- time-dependent density functional theory
- UVA
- ultraviolet A
- TR-FTIR
- infrared transient absorption
- DFT
- density functional theory
- 4-TU
- 4-thiouracil
- U
- uracil
- USO3
- uracil-6-sulfonate
- GSH
- glutathione
- Trp
- tryptophan
- ?G
- electron-transfer driving force
- TrpH
- tryptophan
Chapter 5
- 5-MOP
- 5-methoxypsolaren
- 6-4PPs
- pyrimidine 6-4 pyrimidone photoproducts
- 8-MOP
- 8-methoxypsolaren
- AB
- avobenzone
- AB(E)
- enol form of avobenzone
- AB(K)
- diketone form of avobenzone
- AMP
- adenosine 5´-monophosphate
- ANFX
- N(4´)-acetyl norfloxacin
- AP
- apyrimidinic-apurinic
- BNP
- benoxaprofen
- BP
- benzophenone
- CMP
- cytidine 5´-monophosphate
- CP
- carprofen
- CPDs
- cyclobutane pyrimidine dimers
- CPX
- ciprofloxacin
- Cyd
- 2´-deoxycytidine
- Cyt (3Cyt*)
- cytosine (triplet excited state of cytosine)
- Cyt<>Cyt
- cyclobutane cytosine dimer
- DPA
- dipicolinic acid
- DSB
- double-stranded break
- E. coli
- Escherichia coli
- ?E
- energy gap
- ESIPT
- excited state intramolecular proton transfer
- ET
- triplet energy
- ENX
- enoxacin
- FA
- fenofibric acid
- FLX
- fleroxacin
- FQ
- fluoroquinolone
- GMP
- guanosine 5´-monophosphate
- GV
- gilvocarcin V
- HaCaT
- human keratinocytes cells
- HCT
- hydrochlorothiazide
- HPLC
- high-performance liquid chromatography
- INP (3INP*)
- indoprofen (triplet excited state of indoprofen)
- ISC
- intersystem crossing
- KP (3KP*)
- ketoprofen (triplet excited state of ketoprofen)
- kTTET
- triplet-triplet energy transfer rate constant
- kD
- diffusion-controlled rate constant
- LFX
- lomefloxacin
- LPF
- laser flash photolysis
- MFQ
- mefloquine
- MS
- mass detector
- MS/MS
- tandem mass detector
- N (3N*)
- nucleobase (triplet excited state of nucleobase)
- NSAID
- nonsteroidal anti-inflammatory drug
- NFX
- norlfoxacin
- O2
- molecular oxygen
- 1O2
- singlet oxygen
- OFX
- ofloxacin
- PAGE
- polyacrylamide gel electrophoresis
- PDT
- photodynamic therapy
- PFX
- pefloxacin
- ppRSV
- photoproduct of rosuvastatin
- Ps
- psolaren
- Phs (3Phs*)
- photosensitizer (triplet excited state of photosensitizer)
- Pur
- purine
- PUVA
- psolaren-mediated therapy
- Pyr (1Pyr*) (3Pyr*)
- pyrimidine (singlet excited state of pyrimidine) (triplet excited state of pyrimidine)
- PyPs (3PyPs*)
- pyridopsolaren (triplet excited state of pyridopsolaren)
- S1
- singlet excited state
- SCC
- squamous cell carcinoma
- SP
- spore photoproduct
- RFX
- rufloxacin
- ROS
- reactive oxygen species
- T1
- triplet excited state
- T4 endo V
- T4 endonuclease V
- T-T...
System requirements
File format: ePUB
Copy protection: Adobe-DRM (Digital Rights Management)
System requirements:
- Computer (Windows; MacOS X; Linux): Install the free reader Adobe Digital Editions prior to download (see eBook Help).
- Tablet/smartphone (Android; iOS): Install the free app Adobe Digital Editions or the app PocketBook before downloading (see eBook Help).
- E-reader: Bookeen, Kobo, Pocketbook, Sony, Tolino and many more (not Kindle).
The file format ePub works well for novels and non-fiction books – i.e., „flowing” text without complex layout. On an e-reader or smartphone, line and page breaks automatically adjust to fit the small displays.
This eBook uses Adobe-DRM, a „hard” copy protection. If the necessary requirements are not met, unfortunately you will not be able to open the eBook. You will therefore need to prepare your reading hardware before downloading.
Please note: We strongly recommend that you authorise using your personal Adobe ID after installation of any reading software.
For more information, see our ebook Help page.