The Nucleic Acids

Contributors to Volume IIIPrefaceContents of Volume I and Volume IIErrata, Volume I and Volume II29. Deoxyribonucleic Acids as Macromolecules I. Introduction II. A Brief Survey of the General Principles of the Determination of Weight,Shape,and Dimensions of Large Molecules in Solution III. DNA Particles in Dilute Solutions IV. Conclusions 30. Photochemistry of Nucleic Acids and Their Constituents I. Introduction II. Principles of Photochemistry III. Photochemical Techniques IV. Optical Properties and Techniques V. Photochemistry of Nucleic Acid Constituents VI. Photochemistry of Nucleic Acids VII. Reversibility of Nucleic Acid Photolysis VIII. Radiation Receptors in Living Organisms IX. Viruses X. Photoreactivation XI. Addendum XII. General Bibliography 31. Chemical and Enzymic Synthesis of Polynucleotides I. Abbreviated Formulations and Nomenclature of Polynucleotides II. Chemical Synthesis of Polynucleotides III. Enzymic Synthesis of Ribopolynucleotides IV. Enzymic Synthesis of Deoxyribopolynucleotides 32. Chemistry of the Nucleic Acids of Microorganisms I. Introduction II. Nucleic Acid Content and Dynamics III. Constituents of Nucleic Acids IV. Nucleic Acid Composition and Specificity 33. The Nucleic Acids of the Bacterial Viruses I. Introduction II. Nucleic Acids of the T-Even Phages III. Nucleic Acids of Other T Bacteriophages IV. Nucleic Acids of Temperate Bacteriophages V. Nucleic Acids of Minute Bacteriophages VI. Conclusion 34. The Ribonucleic Acids of Viruses I. Introduction II. Viruses Which Contain Ribonucleic Acid; General Remarks III. The Ribonucleic Acids of Plant Viruses IV. The Ribonucleic Acids of Animal Viruses 35. Biosynthesis of Purine Nucleotides I. Introduction II. Precursors of the Purines III. Enzymic Reactions of Inosinic Acid Synthesis de Novo IV. Enzymic Synthesis of Formyltetrahydrofolic Acid Compounds V. Synthesis of Adenylic Acid from Inosinic Acid VI. Synthesis of Guanylic Acid from Inosinic Acid VII. Summary 36. Biosynthesis of Pyrimidine Nucleotides I. Introduction II. Biosynthesis of Uridine Nucleotides III. Biosynthesis of Cytidine and Deoxycytidine Nucleotides IV. Biosynthesis of Thymidine Nucleotides V. Alternative Pathways of Pyrimidine Nucleotide Synthesis 37. The Relationship of Nucleic Acid and Protein Synthesis as Revealed Studies in Cell-Free Systems I. Introduction II. Participation of Cellular Nucleic Acid-Containing Fractions in Protein Synthesis III. Theoretical Considerations 38. Biosynthesis of Proteins in Intact Bacterial Cells I. Introduction II. Organization of the Bacterial Cell III. Synthesis of Macromolecular Components during Normal Bacterial Growth IV. Uncoupled Synthesis of Macromolecules in Bacteria V. Protein Synthesis After Selective Destruction or Removal of a Nucleic Acid VI. General Discussion VII. Addendum39. Agents Which Influence Nucleic Acid Metabolism I. Introduction II. Compounds Which Interfere with the Formation of Folic Acid-Derived Coenzymes III. Compounds Which Interfere with Amination Reactions in Purine and Pyrimidine Synthesis IV. Structural Analogs of Purines and Their Metabolic Activity V. Structural Analogs of Pyrimidines and Their Effects on Nucleic Acid Metabolism VI. Other Agents Which Influence Nucleic Acid Metabolism VII. Concluding Remarks 40. The Effect of Radiations on Nucleic Acid Metabolism I. Introduction II. Factors Influencing Deoxyribonucleic Acid Specific Activity III. Radiation Effects Within One Interphase IV. The Analysis of the Mechanism of Radiation Effect on DNA Synthesis V. General ConclusionsAuthor Index Subject Index