Basic Radiotherapy Physics and Biology

Atomic and Nuclear Structure.- Radioactive Decay.- Properties and Production of Radiation.- Interactions of Electromagnetic Radiation with Matter.- Interactions of Particulate Radiation with Matter.- Quantification and Measurement of Dose.- Characteristics of Photon Beams.- Dosimetry of Photon Beams in Water.- Dosimetry of Photon Beams in a Patient.- Dosimetry of Electron Beams.- Physics and Dosimetry of Brachytherapy.- Advanced Treatment Planning for EBRT.- Linac Quality Assurance.- Radiation Protection and Safety.- Quality Management Program.- Special Topics: Hyperthermia and Computers.- Molecular Biology and Signaling.- Cancer Genetic and Molecular Characteristics.- Molecular Mechanisms of DNA Damage and Repair.- Cell Death and Survival Assays.- Fractionated Radiation Survival Models.- Oxygen Effect, Relative Biological Effectiveness and Linear Energy Transfer.- Tumor Microenvironment.- Cell and Tissue Kinetics.- Acute Effects of Total Body Irradiation (TBI).- Normal Tissue Radiation Responses.- Therapeutic Ratio.- Combined Modality Therapy.- Biology of Brachytherapy, Particle Therapy, and Alternative Radiation Modalities.- Hyperthermia.- Carcinogenesis and Heritable Effects.- Radiation Effects in the Embryo and Fetus.