Catecholamines: Bridging Basic Science with Clinical Medicine

Name: Catecholamines: Bridging Basic Science with Clinical Medicine
Brand: Academic Press
Price: 200.0 EUR
Availability: OnlineOnly

Academic Press

Published on 20. October 1997

1084 pages

E-Book

PDF with digital watermarking

System requirements

978-0-08-058134-7 (ISBN)

€200.00incl. 7% vat

System requirements

for PDF with digital watermarking

E-Book Single Licence

Available for download

Description

More details

Other editions

Persons

Content

Front Cover
Catecholamines: Bridging Basic Science with Clinical Medicine
Copyright Page
Contents
Contributors
Preface
PART A: CATECHOLAMINE SYNTHESIS AND RELEASE
Overview
Section I: Regulation and Expression of Tyrosine Hydroxylase
Chapter 1. The Effect of Phosphorylation at Ser-40 on the Structure and Thermal Stability of Tyrosine Hydroxylase
Chapter 2. Factors Affecting Adrenal Medullary Catecholamine Biosynthesis and Release
Chapter 3. Regulation of Tyrosine Hydroxylase by Neuropeptides
Chapter 4. Regulation of Tyrosine Hydroxylase Gene Expression by Transsynaptic Mechanisms and Cell-Cell Contact
Chapter 5. A New Regulatory Protein of Catecholamine Synthesizing- Enzyme Expression
Chapter 6. Unique and Cell-Type-Specific Tyrosine Hydroxylase Gene Expression
Chapter 7. Triple Colocalization of Tyrosine Hydroxylase, Calretinin, and Calbindin D-28k in the Periventricular-Hypophyseal Dopaminergic Neuronal System
Chapter 8. Genetic Disorders Involving Recycling and Formation of Tetrahydrobiopterin
Chapter 9. Genetic Basis of Dominant Dystonia
Chapter 10. Mutations in the Tyrosine Hydroxylase Gene Cause Various Forms of L-Dopa-Responsive Dystonia
Chapter 11. Catecholamine Biosynthetic Enzyme Expression in Neurological and Psychiatric Disorders
Section II: Other Catecholamine-Synthesizing Enzymes
Chapter 12. Multiple Pathways in Regulation of Dopamine ß-Hydroxylase
Chapter 13. Examining Adrenergic Roles in Development, Physiology, and Behavior through Targeted Disruption of the Mouse Dopamine ß-Hydroxylase Gene
Chapter 14. Genetic Diseases of Hypotension
Chapter 15. Dopamine ß-Hydroxylase Deficiency Associated with Mutations in a Copper Transporter Gene
Chapter 16. Glucocorticoid-Phenylethanolamine-N-methyltransferase Interactions in Humans
Chapter 17. Determinants of Phenylethanolamine-N- methyltransferase Expression
Chapter 18. Neural Control of Phenylethanolamine-N- methyltransferase via Cholinergic Activation of Egr- I
Chapter 19. Synexin (Annexin VII) Hypothesis for Ca2+/GTP-Regulated Exocytosis
Chapter 20. Monoamine Transmitter Release from Small Synaptic and Large Dense-Core Vesicles
Chapter 21. Calcium Channels for Exocytosis in Chromaffin Cells
Chapter 22. Characteristics of Transmitter Secretion from Individual Sympathetic Varicosities
Chapter 23. Neurotransmitter Release at Individual Sympathetic Varicosities, Boutons
Chapter 24. Appropriate Target Cells Are Required for Maturation of Neurotransmitter Release Function of Sympathetic Neurons in Culture
Chapter 25. Effects of Neuropeptide Y at Sympathetic Neuroeffector Junctions
Chapter 26. Strategies for Receptor Control of Neurotransmitter Release
Chapter 27. Pattern of Adenosine Triphosphate and Norepinephrine Release and Clearance: Consequences for Neurotransmission
Chapter 28. Corelease of Norepinephrine and Adenosine Triphosphate from Sympathetic Neurones
Chapter 29. Neuropeptide Y: An Adrenergic Cotransmitter, Vasoconstrictor, and a Nerve-Derived Vascular Growth Factor
Chapter 30. Neuropeptide Y: A Cardiac Sympathetic Cotransmitter?
Chapter 31. Biochemistry of Somatodendritic Dopamine Release in Substantia Nigra: An in Vivo Comparison with Striatal Dopamine Release
Chapter 32. The Use of Dual-Probe Microdialysis for the Study of Catecholamine Release in the Brain and Pineal Gland
Chapter 33. Kinetics and Geometry of the Excitatory Dopaminergic Transmission in the Rat Striatum in Vivo
Chapter 34. In Vivo and in Vitro Assessment of Dopamine Uptake and Release
PART B: CATECHOLAMINE REUPTAKE AND STORAGE
Overview
Section I: The Plasma Membrane Transporters
Chapter 1. Molecular Physiology and Regulation of Catecholamine Transporters
Chapter 2. Localization of Dopamine Transporter Protein by Microscopic Histochemistry
Chapter 3. Cellular and Subcellular Localization of the Dopamine Transporter in Rat Cortex
Chapter 4. Cloned Catecholamine Transporters Expressed in Polarized Epithelial Cells: Sorting, Drug Sensitivity, and Ion-Coupling Stoichiometry
Chapter 5. Inactivation of the Dopamine Transporter Reveals Essential Roles of Dopamine in the Control of Locomotion, Psychostimulant Response, and Pituitary Function
Chapter 6. Role of Protein Kinase C and Second Messengers in Regulation of the Norepinephrine Transporter
Chapter 7. Electrophysiological Analysis of Transporter Function
Chapter 8. Voltammetric Approaches to Kinetics and Mechanism of the Norepinephrine Transporter
Chapter 9. Voltage-Dependency of the Dopamine Transporter in Rat Brain
Chapter 10. Modulation of Quantal Dopamine Release by Psychostimulants
Chapter 11. Regulation of Dopamine Transporter mRNA Levels in the Central Nervous System
Chapter 12. Structural Diversity in the Catecholamine Transporter Gene Family: Molecular Cloning and Characterization of an L-Epinephrine Transporter from Bullfrog Sympathetic Ganglia
Chapter 13. Positron Emission Tomography Radiogands for Dopamine Transporters and Studies in Human and Nonhuman Primates
Chapter 14. Single Photon Emission Computed Tomography Imaging of Dopaminergic Function: Presynaptic Transporter, Postsynaptic Receptor, and "Intrasynaptic" Transmitter
Chapter 15. Dopamine Transporter Changes in Neuropsychiatric Disorders
Section II: Vesicular Transporters and Catecholamine Storage
Chapter 16. Molecular and Biochemical Studies of Rat Vesicular Monoamine Transporter
Chapter 17. A Chimeric Vesicular Monoamine Transporter Dissociates Sensitivity t o Tetrabenazine and Unsubstituted Aromatic Amines
Chapter 18. Ligand Recognition by the Vesicular Monoamine Transporters
Chapter 19. Molecular Pharmacology of the Vesicular Monoamine Transporter
Chapter 20. Ultrastructural Localization of the Vesicular Monoamine Transporter 2 in Mesolimbic and Nigrostriatal Dopaminergic Neurons
Chapter 21. ICA 512, Receptor Tyrosine Phosphatase-Like Protein, is Concentrated in Neurosecretory Granule Membranes
Chapter 22. Protein Targeting in Neurons and Endocrine Cells
Chapter 23. The Vesicular Monoamine Transporter VMAT2 and Vesicular Acetylcholine Transporter VAChT Are Sorted to Separate Vesicle Populations in PC I 2 Cells
Chapter 24. Recycling of Synaptic Vesicles
Chapter 25. The Secretory Cocktail of Adrenergic Large Dense-Core Vesicles: The Functional Role of the Chromogranins
Chapter 26. A Novel, Catecholamine Release-Inhibitory Peptide from Chromogranin A: Autocrine Control of Nicotinic Cholinergic-Stimulated Exocytosis
Chapter 27. Transcription Regulation Coupled to Calcium and Protein Kinase Signaling Systems through TRE- and CRE-Like Sequences in Neuropeptide Genes
Chapter 28. Imaging of Monoaminergic and Cholinergic Vesicular Transporters in the Brain
PART C: CATECHOLAMINE METABOLISM: FROM MOLECULAR UNDERSTANDING TO CLINICAL DIAGNOSIS AND TREATMENT
Overview
Section I: Monoamine Oxidase
Chapter 1. Monoamine Oxidase A and B: Structure, Function, and Behavior
Chapter 2. Genetic Deficiencies of Monoamine Oxidase Isoenzymes: A Key to Understanding the Function of the Enzymes in Humans
Chapter 3. Biological Markers, with Special Regard to Platelet Monoamine Oxidase (trbc-MAO), for Personality and Personality Disorders
Chapter 4. Visualization of Monoamine Oxidase in Human Brain
Chapter 5. Aliphatic N-Methylpropargylamines: Monoamine Oxidase-B Inhibitors and Antiapoptotic Drugs
Chapter 6. Antiapoptotic Actions of Monoamine Oxidase B Inhibitors
Chapter 7. Therapeutic Actions of L-Deprenyl in Dogs: A Model of Human Brain Aging
Chapter 8. Apomorphine Is a Potent Radical Scavenger and Protects Cultured Pheochromocytoma Cells from 6-OHDA and H2O2-lnduced Cell Death
Section II: O-Methylation and Conjugation
Chapter 9. Catechol O-Methyltransferase: Characterization of the Protein, Its Gene, and the Preclinical Pharmacology of COMT Inhibitors
Chapter 10. X-Ray Crystallography of Catechol O-Methyltransferase: Perspectives for Target-Based Drug Development
Chapter 11. Catechol O-Methyltransferase Inhibition and the Treatment of Parkinson's Disease
Chapter 12. The Structure and Function of the UDP- Glucuronosyltransferase Gene Family
Chapter 13. Catecholamine Sulfation in Health and Disease
Chapter 14. Metabolism of Endobiotics and Xenobiotics by UDP- Glucuronosyltransferase
Section III: Catecholamine Metabolizing Systems
Chapter 15. Molecular Structure of the Carrier Responsible for Hepatic Uptake of Catecholamines
Chapter 16. Catecholamine Uptake and Metabolism in the Liver
Chapter 17. Catecholamine Uptake and Metabolism in Rat Lungs
Chapter 18. The Extraneuronal Monoamine Transporter Exists in Human Central Nervous System Glia
Chapter 19. Removal of Circulating Catecholamines by Extraneuronal Amine Transport Systems
Chapter 20. Catecholamine Metabolites in Internal Jugular Plasma: A Window into the Human Brain
Chapter 21. Norepinephrine Metabolites in Plasma as Indicators of Pharmacological Inhibition of Monoamine Oxidase and Catechol O-Methyltransferase
Chapter 22. The Adrenal Gland as a Source of Dihydroxyphenylalanine and Catecholamine Metabolites
Chapter 23. Clues to the Diagnosis of Pheochromocytoma from the Differential Tissue Metabolism of Catecholamines
PART D: CATECHOLAMINE RECEPTORS AND SIGNAL TRANSDUCTION
Overview
Section I: Structure, Classification, and Tissue Localization of Catecholamine Receptor Subtypes
Chapter 1. Expression and Regulation of a1-Adrenergic Receptors in Human Tissues
Chapter 2. a1-Adrenoceptor Subtypes in the Human Cardiovascular and Urogenital Systems
Chapter 3. Molecular Mechanisms of Ligand Binding and Activation of a1-Adrenergic Receptors
Chapter 4. Expansion of the Dopamine DI Receptor Gene Family: Defining Molecular, Pharmacological, and Functional Criteria for D I A, D I B, D I C, and D I D Receptors
Chapter 5. DI/D3 Receptor Relationships in Brain: Coexpression, Coactivation, and Coregulation
Chapter 6. Mapping the Binding-Site Crevice of the D2 Receptor
Section II: lntracellular Mechanisms
Chapter 7. Mechanisms of ß-Adrenergic Receptor Desensitization and Resensitization
Chapter 8. Role of ß-Arrestins in the Intracellular Trafficking of G-Protein-Coupled Receptors
Chapter 9. G-Protein-Linked Receptors as Substrates for Tyrosine Kinases: Cross-Talk in Signaling
Chapter 10. Role of Arrestins in G-Protein-Coupled Receptor Endocytosis
Chapter 11. Subtype-Specific Regulation of the ß-Adrenergic Receptors
Chapter 12. Structural Determinants of a2-Adrenergic Receptor Regulation
Chapter 13. Regulation of D2 and D3 Receptors in Transfected Cells by Agonists and Antagonists
Chapter 14. Regulation of the D I Dopamine Receptor through CAMP- Mediated Pathways
Chapter 15. Mechanisms for Activation of Multiple Effectors by a1- Adrenergic Receptors
Chapter 16. Signal Transduction Pathways Modulated by D2-Like Dopamine Receptors
Chapter 17. Guanosine Triphosphatase-Activating Proteins for Heterotrimetric G-Proteins
Chapter 18. Regulation of the Stoichiometry of Protein Components of the Stimulatory Adenylyl Cyclase Cascade
Chapter 19. Regulation of Mitogen-Activated Protein Kinase Pathways by Catecholamine Receptors
Section III: Pharmacology
Chapter 20. Examination of Ligand-Induced Conformational Changes in the ß2-Adrenergic Receptor by Fluorescence Spectroscopy
Chapter 21. Relationship between a2-Adrenergic Receptors and Imidazoline/Guanidinium Receptive Sites
Chapter 22. Dopamine D4 Receptors May Alleviate Antipsychotic- Induced Parkonsonism
Chapter 23. Binding of Typical and Atypical Antipsychotic Drugs to Multiple Neurotransmitter Receptors
Chapter 24. Structural and Functional Characteristics of the Dopamine D4 Receptor
Chapter 25. NGD 94- I : A Specific Dopamine-4-Receptor Antagonist
Section IV: Catecholamine Receptors in Physiology and Behavior
Chapter 26. In Vivo Mutation of the a2A-Adrenergic Receptor by Homologous Recombination Reveals the Role of This Receptor Subtype in Multiple Physiological Processes
Chapter 27. Regulation of Fat-Cell Function by a2-Adrenergic Receptors
Chapter 28. The Developmental and Physiological Consequences of Disrupting Genes Encoding ß1 and ß2 Adrenoceptors
Chapter 29. Myocardial Overexpression of Adrenergic Receptors and Receptor Kinases
Chapter 30. Cardiac G-Protein Receptor Kinase Activity: Effect of a ß-Adrenergic Receptor Antagonist
Chapter 31. Structure and Function of the ß3 Adrenoceptor
Chapter 32. Behavioral Analysis of Multiple D I -Like Dopamine Receptor Subtypes: New Agents and Studies in Transgenic Mice with D I A Receptor Knockout
Chapter 33. Antisense Knockdown of Brain Dopamine Receptors
Chapter 34. The Physiological Role of Dopamine D2 Receptors
Section V: Pathophysiological States
Chapter 35. Regulation of D I Receptor Function in Spontaneous Hypertension
PART E: CATECHOLAMINES IN THE PERIPHERY
Overview
Section I: Assessment of Peripheral Catecholaminergic Function
Chapter 1. *Peripheral Catecholaminergic Function Evaluated by Norepinephrine Measurements in Plasma, Extracellular Fluid, and Lymphocytes, from Nerve Recordings and Cellular Responses
Chapter 2. Cardiac Microdialysis
Chapter 3. Sympathetic Microneurography and Neurocirculatory Function: Studies of Ventricular Arrhythmias in Humans
Section II: Catecholamines and Stress
Chapter 4. Stress as a Medical and Scientific Idea and Its Implications
Chapter 5. Stressor Specificity of Peripheral Catecholaminergic Activation
Chapter 6. Stressor-Specific Activation of Catecholaminergic Systems: Implications for Stress-Related Hypothalamic- Pituitary-Adrenocortical Responses
Chapter 7. Regulation of Gene Expression of Catecholamine Biosynthetic Enzymes by Stress
Section III: Catecholamines and Pain
Chapter 8. Peripheral Modulatory Effects of Catecholamines in Inflammatory and Neuropathic Pain
Chapter 9. Brain Catecholamine Systems in Stress
Chapter 10. a2-Adrenergic Mechanisms of Analgesia: Strategies for Improving Their Therapeutic Window and Identification of the Novel, Potent a2A-Adrenergic Receptor Agonist, S 18616
Chapter 11. Cellular Transplantation for Intractable Pain
Section IV: Catecholamines and Neuroimmunology
Chapter 12. The Role of the Sympathetic Nervous System in the Modulation of Immune Responses
Chapter 13. Catecholamines, Catecholamine Receptors, Cell Adhesion Molecules, and Acute Stressor-Related Changes in Cellular Immunity
Chapter 14. Nerve Growth Factor and Autoimmune Disease: Role of Tumor Necrosis Factor- a?
Section V: Adrenomedullary Secretion and Co-Secretion
Chapter 15. Multiple Transmitter Control of Catecholamine Secretion in Rat Adrenal Medulla
Chapter 16. Adrenomedullin in Cardiovascular Disease
Chapter 17. Strychnine, Glycine, and Adrenomedullary Secretion
Section VI: Neurocardiology
Chapter 18. Catecholamines and Neurocardiogenic Syncope
Chapter 19. ß-Blockers in Congestive Heart Failure: The Pharmacology of Carvedilol, a Vasodilating ß-Blocker and Antioxidant, and Its Therapeutic Utility in Congestive Heart Failure
Chapter 20. Sympathetic Cardioneurotherapy in Dysautonomias
Section VII: Catecholamines and Metabolism
Chapter 21. Hypoglycemia-Associated Autonomic Failure in Insulin- Dependent Diabetes Mellitus
Chapter 22. Mechanisms of the Sympathoadrenal Response to Hypoglycemia
Chapter 23. Importance of Catecholamines in Defense against Insulin Hypoglycemia in Humans
Chapter 24. Sympathetic Nervous Activity and the Thermic Effect of Food in Humans
Chapter 25. Microdialysis for the Assessment of Catecholamine-Induced Lipolysis in Human Adipose and Skeletal Muscle Tissue
Section VIII: Catecholamines in the Bruin and Regulation of the Cardiovascular System
Chapter 26. Bulbospinal Cl -Adrenergic Neurons: Electrophysiological Properties in the Neonate Rat
Chapter 27. Catecholamines, Opioids, and Vagal Afferents in the Nucleus of the Solitary Tract
Chapter 28. Agmatine: A Novel Neurotransmitter?
Chapter 29. Central and Peripheral Norepinephrine Kinetics in Heart Failure, Coronary Artery Disease, and Hypertension
PART F: CATECHOLAMINES IN THE CENTRAL NERVOUS SYSTEM
Overview
Chapter 1. Dopamine-Mediated Gene Regulation in the Striatum
Chapter 2. Dopamine Control of Gene Expression in Basal Ganglia Nuclei: Striatal and Nonstriatal Mechanisms
Chapter 3. Dopaminergic Regulation of Immediate Early Gene Expression in the Basal Ganglia
Chapter 4. Dopamine and Calcium Signal Interactions in the Developing Striatum: Control by Kinetics of CREB Phosphorylation
Chapter 5. The Phasic Reward Signal of Primate Dopamine Neurons
Chapter 6. Afferent Control of Midbrain Dopamine Neurons: An lntracellular Perspective
Chapter 7. GABAergic Control of the Firing Pattern of Substantia Nigra Dopaminergic Neurons
Chapter 8. Afferent Control of Substantia Nigra Compacta Dopamine Neurons: Anatomical Perspective and Role of Glutamatergic and Cholinergic Inputs
Chapter 9. Dopamine Axons in Primate Prefrontal Cortex: Specificity of Distribution, Synaptic Targets, and Development
Chapter 10. The Cortical Dopamine System: Role in Memory and Cognition
Chapter 11. Norepinephrine-Dopamine Interactions in the Prefrontal Cortex and the Ventral Tegmental Area: Relevance to Mental Diseases
Chapter 12. Dopamine Function in the Prefrontal Cortex
Chapter 13. The Modulation of Corticoaccumbens Transmission by Limbic Afferents and Dopamine: A Model for the Pathophysiology of Schizophrenia
Chapter 14. Dopamine Modulation of Responses Mediated by Excitatory Amino Acids in the Neostriatum
Chapter 15. The Molecular Basis of Dopamine and Glutamate Interactions in the Striatum
Chapter 16. Modulation by Dopamine of Rat Corticostriatal Input
Chapter 17. Dopamine, Glutamate, and Behavioral Correlates of Striatal Neuronal Activity
Chapter 18. State-Related Activity, Reactivity of Locus Ceruleus Neurons in Behaving Monkeys
Chapter 19. Modulation of Forebrain Electroencephalographic Activity and Behavioral State by the Locus Ceruleus-Noradrenergic System: Involvement of the Medial Septa1 Area
Chapter 20. New Perspectives on the Functional Organization and Postsynaptic Influences of the Locus Ceruleus Efferent Projection System
Chapter 21. Neuromodulation and Cognitive Performance: Recent Studies of Noradrenergic Locus Ceruleus in Behaving Monkeys
Chapter 22. Noradrenergic Effects on Activity of Prefrontal Cortical Neurons in Behaving Monkeys
Chapter 23. Noradrenergic Influences on Prefrontal Cortical Cognitive Function: Opposing Actions at Postjunctional a1- Versus a2-Adrenergic Receptors
Chapter 24. Afferent Control of Nucleus Locus Ceruleus: Differential Regulation by "Shell" and "Core" Inputs
Chapter 25. Sensory Response of the Locus Ceruleus: Neonatal and Adult Studies
Chapter 26. Noradrenergic Modulation of the Prefrontal Cortex as Revealed by Electron Microscopic Immunocytochemistry
Chapter 27. Activation of the Locus Ceruleus Brain Noradrenergic System during Stress: Circuitry, Consequences, and Regulation
Chapter 28. Norepinephrine and Schizophrenia: A New Hypothesis for Antipsychotic Drug Action
Chapter 29. Neurochemical Responses to Lesions of Dopaminergic Neurons: Implications for Compensation and Neuropathology
Chapter 30. Dopamine Receptor Subtypes as Targets for the Pharmacotherapy of Parkinson's Disease
Chapter 31. Free Radicals and MPTP-Induced Selective Destruction of Substantia Nigra Compacta Neurons
Chapter 32. Application of Gene Therapy for Parkinson's Disease: Nonhuman Primate Experience
Chapter 33. Prefrontal Cortical and Hippocampal Modulation of Dopamine-Mediated Effects
Chapter 34. Dysregulation of Mesoprefrontal Dopamine Neurons Induced by Acute and Repeated Phencyclidine Administration in the Nonhuman Primate: Implications for Schizophrenia
Chapter 35. Interactions between Catecholamines and Serotonin: Relevance to the Pharmacology of Schizophrenia
PART G: NOVEL CATECHOLAMINERGIC SYSTEMS
Overview
Section I: Catecholestrogens
Chapter 1. Catecholestrogens in the Induction of Tumors in the Kidney of the Syrian Hamster
Chapter 2. Biosynthesis and Inactivation of Catecholestrogens
Chapter 3. Catecholestrogens as Procarcinogens: Depurinating Adducts and Tumor Initiation
Chapter 4. Role of Aromatic Hydrocarbons in Disclosing How Catecholestrogens Initiate Cancer
Chapter 5. Embryo Implantation Requires Estrogen-Directed Uterine Preparation and Catecholestrogen-Mediated Embryonic Activation
Section II: Nonneuronal Biosynthesis of Catecholamines
Chapter 6. Extra-Adrenal Nonneuronal Epinephrine and P henylethanolamine-N-methyltransferase
Chapter 7. Dopamine and the Brain-Gut Axis
Chapter 8. Origin and Significance of Plasma Dihydroxyphenylalanine
Section III: Is L-Dopa Neurotransmitter?
Chapter 9. Is L-Dopa a Neurotransmitter of the Primary Baroreceptor Afferents Terminating in the Nucleus Tractus Solitarri of Rats?
Chapter 10. lmmunocytochemical Evidence of Novel Catecholamine- or Biopterin-Related Neurons of Mammalian Brain
Chapter 11. Fluorinated Dihydroxyphenylserines as Potential Biological Precursors of Fluorinated Norepinephrines
Section IV: Dopamine as a Renal Autocrine-Paracrine Substance
Chapter 12. Nonneuronal Dopamine
Chapter 13. The Renal Dopamine System
Chapter 14. Renal Dopamine Production and Release in the Rat: A Microdialysis Study
PART H: DEVELOPMENT AND PLASTICITY
Overview
Chapter 1. Inductive Interactions Underlie Neural Crest Formation
Chapter 2. Lineage Commitment and Fate of Neural Crest-Derived Neurogenic Cells
Chapter 3. The Differentiation of the Neurotransmitter Phenotypes in Chick Sympathetic Neurons
Chapter 4. Developmental Regulation of Neurotransmitters in Sympathetic Neurons
Chapter 5. Changes in Gene Expression in Adult Sympathetic Neurons after Axonal Injury
Chapter 6. Ontogeny of Vesicular Amine Transporter Expression in the Rat: New Perspectives on Aminergic Neuronal and Neuroendocrine Differentiation
Chapter 7. Specification and Survival of Dopaminergic Neurons in the Mammalian Midbrain
Chapter 8. Effects of Glial Cell Line-Derived Neurotrophic Factor on the Nigrostriatal Dopamine System in Rodents and Nonhuman Primates
Chapter 9. Cell Body Functions of Brain-Derived Neurotrophic Factor Increase Forebrain Dopamine Release and Serotonin Metabolism Determined with in Vivo Microdialysis
Chapter 10. Neurotrophin Modulation of Hippocampal Synaptic Transmission
Chapter 11. Genotype and Phenotype in Familial Dysautonomia
Chapter 12. A Gene Therapy Approach for the Treatment of Amyotrophic Lateral Sclerosis and Parkinson's Disease
Chapter 13. Characterization of Adrenal Chromafin Progenitor Cells in Mice
Chapter 14. Evolution and Origin of the Diversity of Dopamine Receptors in Vertebrates
Chapter 15. Neurogenetics of Synaptic Transmission in Caenorhabditis elegans
Chapter 16. Decapitated Drosophila: A Novel System for the Study of Biogenic Amines
Chapter 17. Dopaminergic Control of Serotonergic Neuron Development in the Grasshopper Central Nervous System
Chapter 18. Noradrenergic Long-Term Potentiation in the Dentate Gyrus
Chapter 19. Rapid Acquisition of Discriminative Responding in Monkey Locus Coeruleus Neurons
Chapter 20. Catecholaminergic Contributions to Early Learning
Chapter 21. Interactions between Catecholamines and the Amygdala in Emotional Memory: Subclinical and Clinical Evidence
PART I: DRUG ABUSE AND ALCOHOLISM
Overview
Chapter 1. Circuits, Drugs, and Drug Addiction
Chapter 2. Homologies and Differences in the Actions of Drugs of Abuse and a Conventional Reinforcer (Food) on Dopamine Transmission: An Interpretative Framework of the Mechanism of Drug Dependence
Chapter 3. Drug-Induced Adaptations in Catecholamine Systems: On the Inevitability of Sensitization
Chapter 4. Neurobiological Substrates Underlying Conditioned Effects of Cocaine
Chapter 5. The Rate Hypothesis and Agonist Substitution Approaches to Cocaine Abuse Treatment
Chapter 6. Drugs of Abuse and Dopamine Cell Activity
Chapter 7. DI -Receptor Regulation of Synaptic Potentials in the Ventral Tegmental Area after Chronic Drug Abuse
Chapter 8. Neuroadaptations in Nucleus Accumbens Neurons Resulting from Repeated Cocaine Administration
Chapter 9. Dopamine Efflux Studies into the in Vivo Actions of Psychostimulant Drugs
Chapter 10. Psychostimulants and Neuropeptide Response
Chapter 11. Drugs of Abuse and Striatal Gene Expression
Chapter 12. Coordinated Expression of Dopamine Receptors in Neostriatal Medium Spiny Neurons
Chapter 13. Dopaminergic Genes and Substance Abuse
Chapter 14. Quantitative Trait Loci: Mapping Drug and Alcohol- Related Genes
Chapter 15. Nuclear Memory: Gene Transcription and Behavior
Chapter 16. Phosphorylation of Dopamine Transporters and Rapid Adaptation to Cocaine
Index
Contents of Previous Volumes

System requirements

Save as PDF Copy link into clipboard

Schweitzer Fachinformationen

Catecholamines: Bridging Basic Science with Clinical Medicine

Description

More details

Other editions

Additional editions

Persons

Content

System requirements