
Clinical Reproductive Science
Description
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The field of clinical reproductive science continues to evolve; this important resource offers the basics of reproductive biology as well as the most recent advance in clinical embryology. The author - a noted expert in the field - focuses on the discipline and covers all aspects of this field. The text explores causes of male and female infertility and includes information on patient consultation and assessment, gamete retrieval and preparation, embryo culture, embryo transfer and cryopreservation.
Comprehensive in scope, the text contains an introduction to the field of clinical reproductive science and a review of assisted reproductive technology. The author includes information on a wide range of topics such as gonadal development, the regulation of meiotic cell cycle, the biology of sperm and spermatogenesis, in vitro culture, embryo transfer techniques, fundamentals of fertilisation, oocyte activation and much more. This important resource:
* Offers an accessible guide to the most current research and techniques to the science of clinical reproduction
* Covers the fundamental elements of reproductive science
* Includes information on male and the female reproductive basics - everything from sexual differentiation to foetal development and parturition
* Explores the long-term health of children conceived through IVF
* Contains the newest developments in assisted reproductive technology
Clinical Reproductive Science is a valuable reference written for professionals in academia, research and clinical professionals working in the field of reproductive science, clinical embryology and reproductive medicine.
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Person
About the Editor
MICHAEL CARROLL, Senior Lecturer in Reproductive Science, School of Healthcare Science, Manchester Metropolitan University, UK
Content
List of Contributors xi
About the Editor xv
Preface xvii
Acknowledgements xix
About the Companion Website xxi
Section One Reproductive Science: Fundamentals of Human Reproductive Biology 1
1 Sexual Differentiation, Gonadal Development, and Development of the External Genitalia: A Review of The Regulation of Sexual Differentiation 3 Rebecca M. Perrett
2 Male and Female Reproductive Anatomy 35 Sara Sulaiman and James Coey
3 Fundamentals of Reproductive Endocrinology 45 Derrick Ebot, Haider Hilal, Michael Carroll, and James Coey
4 The Ovaries, Oocytes, and Folliculogenesis 57 Jacques Gilloteaux and James Coey
5 The Human Spermatozoa 65 Allan Pacey and Katrina Williams
6 The Biology of Fertilization 75 Michael Carroll
7 Human Embryo Development: From Zygote Stage to Peri-Implantation Blastocyst 93 Stéphane Berneau and Michael Carroll
8 The Female Reproductive Tract and Early Embryo Development: A Question of Supply and Demand 99 Henry J. Leese and Daniel R. Brison
Section Two Clinical Reproductive Science: Causes of Male and Female Infertility 109
9 Disorders of Male Reproductive Endocrinology 111 Michael Carroll
10 Disorders of Female Reproductive Endocrinology 125 Mahshid Nickkho-Amiry and Cheryl T. Fitzgerald
11 Oocyte Aneuploidy and the Maternal Age Effect 133 Mary Herbert
12 Female Reproductive Pathology: Peritoneal, Uterine, and Fallopian Tube Pathologies 147 Kenneth Ma Kin Yue, Rosa Trigas, and Edmond Edi-Osagie
13 Pathologies of the Male Reproductive Tract 159 Aarush Sajjad, Muhammad A. Akhtar, and Yasmin Sajjad
14 The Impact of Infections on Reproduction and Fertility 177 Val Edwards Jones
15 Nutrition, Fetal Health, and Pregnancy 189 Emma Derbyshire
16 The Embryonic Environment and Developmental Origins of Health 195 Tom P. Fleming and Congshan Sun
17 Lifestyle and Environmental Impacts on Fertility 205 Ana-Maria Tomova and Michael Carroll
Section Three Clinical Reproductive Science In Practice: IVF and Assisted Reproductive Technologies 215
18 Assessing the Infertile Couple 217 Narmada Katakam, Ruth Arnesen, Caroline Watkins, Bert Stewart, and Luciano G. Nardo
19 Ovarian Stimulation Protocols 231 Nikolaos Tsampras and Cheryl T. Fitzgerald
20 Oocyte Retrieval Techniques and Culture of Oocytes 241 Dawn Yell
21 Sperm Preparation: Strategy and Methodology 251 Stephen Harbottle
22 Diagnostic Semen Analysis: Uncertainty, Clinical Value, and Recent Advances 265 Mathew Tomlinson
23 Surgical Sperm Retrieval 279 Muhammad A. Akhtar, Elizabeth Hester, Solmaz Gul Sajjad, and Yasmin Sajjad
24 In Vitro Fertilization and Intracytoplasmic Sperm Injection 291 Bryan Woodward
25 Morphological Assessment of Embryos in Culture 303 J. Diane Critchlow
26 In Vitro Culture of Gametes and Embryos - The Culture Medium 317 Robbie Kerr
27 Incubators in the Assisted Reproductive Technology Laboratory 333 Louise Hyslop
28 Embryo Transfer Techniques and Improving Embryo Implantation Rates 341 Rachel Cutting
29 Cryopreservation of Gametes and Embryos 351 Tope Adeniyi
30 Preimplantation Genetic Diagnosis and Screening 371 Colleen Lynch and Brendan Ball
31 Long-Term Follow-Up of Children Conceived Through In Vitro Fertilization 385 Omar Abdel-Mannan and Alastair G. Sutcliffe
Index 393
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