Biochips as Pathways to Drug Discovery
Published on 19. October 2006
386 pages
978-1-4200-1560-7 (ISBN)
Description
In the fiercely competitive pharmaceutical marketplace, your organization cannot afford to spend excess dollars developing drugs that will fail to get FDA approval or have profoundly poor characteristics. Biochips as Pathways to Drug Discovery takes a comprehensive look at how the industry faces these challenges, using new technologies such as bioc
Reviews / Votes
"The authors of this volume provide an in-depth review of the clinical and pharmacogenomic relevance of biochips, ChIP-chip assays, and high-throughput approaches. ... The book includes coverage of experimental theory, quality control, clinical laboratory sampling considerations, database concepts, industrial laboratory design, and the analysis of the resultant large data sets. ... Written in an easily accessible style, the breadth of coverage introduces the subject to those new to the field, while the depth of coverage forms a foundation for future work."- In Anticancer Research, Vol. 27, No. 3B, May/June 2007
"This book is a must have for students who use biochips in their graduate work or others initiating efforts in these areas . . . In summary, Biochips as Pathways to Drug Discovery provides a broad yet detailed look at the use of DNA microarrays in drug discovery."
- Matthew D. Disney, The University at Buffalo, The State University of New York, in ChemMedChem, 2008, No. 3
More details
Series
Language
English
Place of publication
Baton Rouge
United States
Publishing group
Taylor & Francis Inc
Target group
Professional and scholarly
Researchers and engineers in biochemistry and pharmaceuticals.
Illustrations
93 s/w Abbildungen, 14 farbige Abbildungen, 18 s/w Tabellen, 23 s/w Photographien bzw. Rasterbilder
93 b/w images, 14 color images, 18 tables and 23 halftones
File size
11,56 MB
ISBN-13
978-1-4200-1560-7 (9781420015607)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Andrew Carmen | Gary Hardiman
Biochips as Pathways to Drug Discovery
Book
10/2006
1st Edition
CRC Press
€101.70
Shipment within 15-20 days
Persons
Content
DNA Biochips- Past, Present, and Future: An Overview. Three-Dimensional HydroArrays: Novel Microarrays for Genomic and Proteomic Studies. Biochip in Malaria for Antiparasitic Discovery. Regional Variations in Intestinal ATP-Binding Cassette Transporter Expression Identified with a Global Error Assessment Model. Toxicogenomics in Drug Safety Evaluation: Bridging Drug Discovery and Development. The Next Generation of Automated Microarray Platforms for a Multiplexed CYP2D6 Assay. Biopsy and RNA Extraction Procedures of Muscle and Adipose Tissue for Microarray Gene-Expression Profiling. ChIP-on-Chip: Analysis of Genomewide Protein Binding and Posttranslational Modifications. DNA Microarrays as Functional Genomics Tools for Cancer Drug Discovery. High-Throughput Microarray Analysis. Laboratory Automation: Strategies for High-Volume Industrial Microarray Programs. Association Studies: Practical and Theoretical Considerations for Drug Discovery, Evaluation, and Beyond. Approaches for Microarray Data Validation. Microarray Enterprise Information Management: What Is It and Why Is It Important? Quality Control of Microarray Data. Microarray Data Normalization and Transformation. Amplification Strategies and DNA Biochips. Ribo-SPIA , a Rapid Isothermal RNA Amplification Method for Gene Expression Analysis. Genomics, Transcriptomics, and Proteomics: Novel Detection Technologies and Drug Discovery. Intellectual Property Issues for DNA Chips and Microarrays. Biochips: Market Drivers and Commercial Prospect. A Pharmaceutical Perspective for Microarrays and Biochips: Current-Market Overview and Future Trends.
