
Graphs in Biomedical Image Analysis, Computational Anatomy and Imaging Genetics
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The 7 full papers presented at GRAIL 2017, the 10 full papers presented at MFCA 2017, and the 5 full papers presented at MICGen 2017 were carefully reviewed and selected. The GRAIL papers cover a wide range of graph based medical image analysis methods and applications, including probabilistic graphical models, neuroimaging using graph representations, machine learning for diagnosis prediction, and shape modeling. The MFCA papers deal with theoretical developments in non-linear image and surface registration in the context of computational anatomy. The MICGen papers cover topics in the field of medical genetics, computational biology and medical imaging.
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Content
- Intro
- Workshop Editors
- Preface GRAIL 2017
- Organization
- Preface MFCA 2017
- Organization
- Preface MICGen 2017
- Organization
- Contents
- First International Workshop on Graphs in Biomedical Image Analysis, GRAIL 2017
- Classifying Phenotypes Based on the Community Structure of Human Brain Networks
- 1 Introduction
- 2 Similarity of Brain Network Community Structures
- 2.1 Detecting Communities in Structural Brain Networks
- 2.2 Measuring Distance Between Community Structures
- 3 Classifying Connectomes Based on their Community Structure
- 4 Experiments: Network-Based Alzheimer's Disease Classification
- 4.1 Data and Network Construction
- 4.2 Experimental Setup
- 4.3 Results and Discussion
- 5 Conclusions
- References
- Autism Spectrum Disorder Diagnosis Using Sparse Graph Embedding of Morphological Brain Networks
- 1 Introduction
- 2 Proposed Sparse Graph Embedding of High-Order Morphological Brain Networks for Autism Classification
- 3 Results and Discussion
- 4 Conclusion
- References
- Topology of Surface Displacement Shape Feature in Subcortical Structures
- 1 Introduction
- 2 Methods
- 2.1 Shape Feature
- 2.2 Shape Topology
- 2.3 Persistent Homology
- 2.4 Experiments
- 2.5 Imaging and Demographics
- 3 Results
- 4 Discussion and Conclusion
- References
- Graph Geodesics to Find Progressively Similar Skin Lesion Images
- 1 Introduction
- 2 Methods
- 3 Results
- 4 Conclusions
- References
- Uncertainty Estimation in Vascular Networks
- 1 Introduction
- 2 Background
- 3 Uncertainty Estimation by Means of Sampling
- 3.1 Perturbation Sampler
- 3.2 Gibbs Sampler
- 4 Experiments and Results
- 5 Conclusion
- References
- Extraction of Airways with Probabilistic State-Space Models and Bayesian Smoothing
- 1 Introduction
- 2 Method
- 2.1 Tracking Individual Branches
- 2.2 Process and Measurement Models
- 2.3 Bayesian Smoothing
- 2.4 Tree as a Collection of Branches
- 2.5 Application to Airways
- 3 Experiments and Results
- 3.1 Data
- 3.2 Error Measure, Initial Parameters and Tuning
- 3.3 Results
- 4 Discussion and Conclusions
- References
- Detection and Localization of Landmarks in the Lower Extremities Using an Automatically Learned Conditional Random Field
- 1 Introduction
- 2 Related Work
- 3 Methods
- 3.1 Landmark Localization Using Regression Tree Ensembles
- 3.2 CRF with Pool of Potential Functions and ``Missing'' Label
- 3.3 Learning of Parameters and Removing Potentials
- 4 Results
- 5 Discussion and Conclusions
- References
- 6th International Workshop on Mathematical Foundations of Computational Anatomy, MFCA 2017
- Bridge Simulation and Metric Estimation on Landmark Manifolds
- 1 Introduction
- 2 Landmarks Manifolds and Stochastic Landmark Dynamics
- 2.1 Brownian Motion
- 2.2 Large Deformation Stochastics
- 3 Brownian Bridge Simulation
- 3.1 Bridge Sampling
- 3.2 Landmark Bridge Simulation
- 4 Inference Algorithm
- 5 Numerical Experiments
- 5.1 Left Cardiac Ventricles
- 6 Conclusion
- References
- White Matter Fiber Segmentation Using Functional Varifolds
- 1 Introduction
- 2 White Matter Fiber Segmentation Using Functional Varifolds
- 2.1 Modeling Fibers Using Functional Varifolds
- 2.2 Fiber Clustering Using Dictionary Learning and Sparse Coding
- 3 Experiments
- 4 Conclusion
- References
- Prediction of the Progression of Subcortical Brain Structures in Alzheimer's Disease from Baseline
- 1 Introduction
- 2 Method
- 2.1 Geodesic Regression
- 2.2 Two Methods to Transport Spatiotemporal Trajectories of Shapes
- 2.3 Cognitive Scores Dynamics
- 3 Results
- 3.1 Data, Preprocessing, Parameters and Performance Metric
- 3.2 Geodesic Regression Extrapolation
- 3.3 Non Reparametrized Transport
- 3.4 Refining with Cognitive Dynamical Parameters
- 4 Conclusion
- References
- A New Metric for Statistical Analysis of Rigid Transformations: Application to the Rib Cage
- 1 Introduction
- 2 Defining an Adapted Metric for Elongated Structures
- 2.1 Limits of the Current Metric
- 2.2 A New Metric for Elongated Objects
- 3 Statistical Description of Rigid Transformations
- 3.1 Pose Variations
- 3.2 Generalized Covariance
- 3.3 Application to the Rib Cage
- 4 Conclusion
- References
- Unbiased Diffeomorphic Mapping of Longitudinal Data with Simultaneous Subject Specific Template Estimation
- 1 Introduction
- 2 Methods
- 2.1 Diffeomorphisms and Geodesics
- 2.2 Sparse Parameterization
- 2.3 Group Actions and Notation
- 2.4 Cost Function for Timeseries Mapping
- 2.5 Optimization Algorithm
- 2.6 Atrophy in the Medial Temporal Lobe
- 3 Results
- 3.1 Template Estimation and Longitudinal Mapping
- 3.2 Processing Bias
- 4 Conclusion
- References
- Exact Function Alignment Under Elastic Riemannian Metric
- 1 Introduction
- 2 Mathematical Background
- 3 Pairwise Alignment Theory
- 4 The Matching Algorithm
- 4.1 The Contribution of an Up- or Down-Segment
- 4.2 The Matching Graph
- 4.3 Finding Optimal Matching
- 5 Multiple Function Alignment
- 6 Experimental Results
- 7 Conclusion
- References
- Varifold-Based Matching of Curves via Sobolev-Type Riemannian Metrics
- 1 Introduction
- 2 Mathematical Background
- 2.1 Sobolev Metrics on Shape Space of Curves
- 2.2 Varifold Distance on the Space of Curves
- 2.3 Inexact Matching on the Shape Space of Curves
- 3 Implementation
- 4 Experiments
- 5 Conclusions
- References
- Computational Anatomy in Theano
- 1 Introduction
- 1.1 Background
- 2 Geodesics
- 3 Christoffel Symbols
- 4 Fréchet Mean
- 5 Normal Distributions and Stochastic Development
- 6 Fréchet Mean on Frame Bundle
- 7 Conclusion
- References
- Rank Constrained Diffeomorphic Density Motion Estimation for Respiratory Correlated Computed Tomography
- 1 Introduction
- 2 Low Rank Motion Estimation
- 3 Singular Value Thresholding and Implementation
- 4 Application to Respiratory 4DCT Phase Registration
- 5 Discussion
- References
- Efficient Parallel Transport in the Group of Diffeomorphisms via Reduction to the Lie Algebra
- 1 Introduction
- 2 Background on Diffeomorphisms and LDDMM
- 2.1 Diffeomorphisms
- 2.2 LDDMM Image Registration
- 2.3 Decoupling Diffeomorphisms from Images
- 3 Parallel Transport
- 3.1 Parallel Transport Equation
- 3.2 Computational Complexity Analysis
- 3.3 Implementation Details
- 4 Experiments
- 4.1 Synthetic Data
- 4.2 Real Data
- 5 Conclusion
- References
- Third International Workshop on Imaging Genetics, MICGen 2017
- Multi-modal Image Classification Using Low-Dimensional Texture Features for Genomic Brain Tumor Recognition
- 1 Introduction
- 2 Methods
- 2.1 Bag-of-Patterns: From Local Image Features to Image Region Descriptors
- 2.2 Unsupervised Feature Learning Based on Deep Auto-Encoders
- 3 Experiments
- 4 Conclusion
- References
- A Fast SCCA Algorithm for Big Data Analysis in Brain Imaging Genetics
- 1 Introduction
- 2 The Fast SCCA Algorithm
- 3 Experiments
- 3.1 Results on Synthetic Data
- 3.2 Results on Real Neuroimaging Genetics Data
- 4 Conclusions
- References
- Transcriptome-Guided Imaging Genetic Analysis via a Novel Sparse CCA Algorithm
- 1 Introduction
- 2 Problem Formulation
- 3 Methods
- 3.1 Update of u with v fixed
- 3.2 Update of v with u fixed
- 4 Experimental Results and Discussions
- 4.1 Selection of Tuning Parameters , c1 and c2
- 4.2 Results
- 5 Conclusions
- References
- Multilevel Modeling with Structured Penalties for Classification from Imaging Genetics Data
- 1 Introduction
- 2 Model Set-up
- 2.1 Multilevel Logistic Regression with Structured Penalties
- 2.2 Minimization of , I, I, 0)
- 3 Experimental Results
- 3.1 Dataset
- 3.2 Results
- 4 Conclusion
- A Probabilistic Formulation
- References
- Coupled Dimensionality-Reduction Model for Imaging Genomics
- 1 Introduction
- 2 SCyLIG Model for Imaging Genomics
- 2.1 Dictionary Learning Methods
- 2.2 SCyLIG Formulation
- 2.3 SCyLIG Optimization
- 3 Experiments
- 4 Conclusion
- References
- Author Index
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