Cell Synchrony

List of ContributorsPrefaceChapter 1 Cell Synchrony, a Prologue to Discovery I. Introduction II. A Concept of Cell Synchrony III. Synchrony and the Evolution of Cell Types ReferencesChapter 2 On the Theory of Synchronous Cultures I. Introduction II. Finite Difference Conventions III. Doubling-Time Distributions IV. Ergodic Cultures V. Growth Curve Prediction VI. Determination of the Cell Doubling-Time Distribution Function from the Decay of Synchronization VII. The Initial State of a Culture VIII. The State Function IX. Degree of Synchronization X. Age Distribution XI. Steady-State Growth XII. A Numerical Example XIII. Nonergodic Cultures: Cyclic Synchronous Cultures XIV. Resumé ReferencesChapter 3 Synchronous Replication of the Chromosome in Bacillus Subtilis I. Introduction II. Nonsynchronous Replication III. Synchrony of Chromosome Replication IV. Applications of Chromosome Synchrony V. Future Problems ReferencesChapter 4 Chromosome Replication in Escherichia coli I. Introduction II. The Escherichia coli Systems III. Sequential Replication of the Escherichia coli Chromosome IV. Regulation of Sequential Chromosome Synthesis V. Measuring Changes in the Sequential Pattern of Replication VI. Studies on the Mechanism Controlling Initiation of DNA Synthesis: Use of Inhibitors VII. Cell Division and the Regulation of Chromosome Replication VIII. Heterogeneity in the Resumption of DNA Synthesis after the Completion of a Chromosome Replication Cycle IX. Rate of Chromosome Replication X. Attempts to Characterize the Physical State of Replicating DNA XI. The Regulation of Chromosome Replication ReferencesChapter 5 Nuclear Events in Synchronously Dividing Yeast Cultures I. Introduction II. Nucleic Acid Synthesis in Synchronously Dividing Cultures III. Cytological Observations on Synchronously Dividing Cultures IV. General Conclusions Addendum ReferencesChapter 6 Periodic Enzyme Synthesis in Synchronous Cultures of Yeast I. The Use of Synchronous Cultures for Studying Cellular Biosynthesis II. Ordered Transcription During the Division Cycle III. The Periodicity of Enzyme Synthesis IV. The Relationship Between Gene Position and the Time of Enzyme Synthesis V. Possible Mechanisms for Controlling Sequential Transcription ReferencesChapter 7 Light-Induced Synchronous Sporulation of a Myxomycete-The Relation of Initial Metabolic Changes to the Establishment of a New Cell State I. Introduction II. Changes in Plasmodial Macromolecular Components During the Dark and Light Periods III. Light-Induced Changes in the Plasmodial ATP Level IV. Inhibition of Respiration by Light V. Evidence of Light-Dependent Oxidation-Reduction Reactions VI. Metabolism and Nature of the Yellow Pigment VII. Melanogenesis VIII. Some Observations on Energy-Controlled Metabolism Relating to Morphogenesis IX. Summary ReferencesChapter 8 Studies on Chloroplast Replication in Synchronized Euglena I. Introduction II. Physiological Reproduction III. Biochemical Reproduction IV. Morphological Reproduction V. Role of Chloroplast Development in Synchronizing Euglena VI. Summary ReferencesChapter 9 Silica Shell Formation in Synchronously Dividing Diatoms I. Introduction II. Methods for Inducing Synchrony III. Physiological Studies of Silicon Uptake and Shell Formation IV. Morphological Development of Silica Shell v. General Conclusions ReferencesChapter 10 Intracellular Control of Enzyme Synthesis and Activity During Synchronous Growth of Chlorella i. Introduction II. Organism and Growth Characteristics III. Metabolic Shifts During Synchronous Growth IV. Intracellular Control of RNA and DNA Synthesis v.