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The Cell Nucleus, Volume II covers mainly the chromosomes, including its pathology. It also reviews the information onthe isolated mitotic apparatus highlighting on its chemistryand relevant morphology. This volume particularly discusses the mammalian chromosomes, the staining techniques, the kinetics of DNA replication in chromosomes, and the difference of meiotic chromosomes from mitotic chromosomes. It also presents studies on isolated mammalian metaphase chromosomes; chromosomes of birds and plants; as well as the polytene chromosomes of the two-winged insects, the Diptera. Furthermore, this volume describes the giant chromosomes. Lastly, the autosomal disorders, the abnormalities of sex development, and types of virus-induced chromosome alterations are explained to elucidate the pathology of chromosome.
Language
Place of publication
Publishing group
Elsevier Science & Techn.
ISBN-13
978-0-323-14507-7 (9780323145077)
Schweitzer Classification
List of Contributors Preface Contents of Other Volumes IntroductionPart I Chromosomes-General Chapter 1 Mammalian Chromosomes I. Introduction II. DNA Content, Chromosome Number, and Chromosome Morphology III. Sex Chromosomes IV. Heterochromatin V. Cytochemical Differentiation of Chromosomal Regions VI. Somatic Cell Hybridization VII. Chromosomes in Evolution References Chapter 2 The Human Cell Nucleus: Quinacrine and Other Differential Stains in the Study of Chromatin and Chromosomes I. Perspectives on Human and Medical Cytogenetics II. Human Chromosome Identification III. Human Chromosome Polymorphisms IV. Study of Chromosome Abnormalities V. Chromosome Abnormalities in Malignancies VI. Paternity Studies VII. Parental Origin of Chromosome Abnormalities VIII. Gene Mapping Using Chromosome Polymorphisms, Rearrangements,and Somatic-Cell Hybridization IX. Chromatin: Differentially Marked Regions on Autosomes and the Y in Interphase X. Meiotic Chromosomes XI. Chromosome Evolution and Banding References Chapter 3 Studies of Isolated Mammalian Metaphase Chromosomes I. Introduction II. Isolation of Metaphase Chromosomes III. Chemical Composition of Metaphase Chromosomes IV. Studies with Fractionated Metaphase Chromosomes V. The Structure of Metaphase Chromosomes VI. Conclusions References Chapter 4 The Kinetics of DNA Replication in Chromosomes I. Introduction II. The Replicon III. The Replicon Series IV. The Chromosome V. Discussion VI. Conclusions References Chapter 5 The Organization of Meiotic Chromosomes I. Introduction II. General Organization of DNA in Chromosomes III. Special Features of Meiotic Chromosomes IV. Relation of Chromosome Structure to Meiotic Chromosome Behavior V. Summary and Conclusions References Chapter 6 Progress in Human Gene Mapping by Somatic Cell Hybridization I. Introduction II. Methodology and Rationale of Human Gene Mapping III. Assignments of Genes to Human Chromosomes IV. Regional Localization of Human Genes V. Conclusion ReferencesPart II Chromosomes-Specific Chapter 7 Chromosomes of Birds I. Introduction II. Phylogeny of Birds and Genome Size III. Mitotic Chromosomes IV. Meiotic Chromosomes V. Heterochromatin VI. Heteroploidy VII. Summary References Chapter 8 Plant Cytogenetics I. Physical and Chemical Constitution of Chromosomes II. Behavior of Chromosomes in Different Tissues III. Differentiation of Chromosome Segments IV. Numerical and Structural Variability of Chromosome Complement-Origin and Role V. Size and Morphology of Chromosomes in Evolution VI. Karyotype as an Aid in Taxonomy VII. Conclusion References Chapter 9 Polytene Chromosomes in Studies of Gene Expression I. Introduction II. DNA Content of the Chromosome Band III. Genetic Equivalent of the Chromosome Band IV. Relation of Puffing to Gene Activity V. The Transcriptory Activity VI. Release of Chromosomal RNA to the Nuclear Sap VII. Puff RNA in the Cytoplasm VIII. Conclusions and Perspectives References Chapter 10 Giant Chromosomes I. Structural Organization of Giant Chromosomes II. Metabolic Activities of Giant Chromosomes III.