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The Structure and Function of Nervous Tissue, Volume VI: Structure IV and Physiology IV covers topics pertaining to ependyma and subependymal layer, filaments and tubules, synapse, epiphysis cerebri, excitation, macromolecules, and dopamine in the nervous system. The book particularly discusses the main structural features and functions of the ependyma and subependymal layer. It describes the ultrastructure of the synapse, and the nonspecific changes of the central nervous system in normal and experimental materials. It also includes the molecular biology of developing mammalian brain. In addition, the ""macromolecular picture"" of nerve excitation based on accumulated experimental findings from intracellularly perfused squid giant axons is presented. Lastly, evidence pertaining to the view that dopamine plays an important role in the control of extrapyramidal (striatal) motor functions is shown. This book will be very useful for graduate students in a variety of disciplines and for those specializing in particular aspects of nervous tissue study.
Language
Place of publication
Publishing group
Elsevier Science & Techn.
ISBN-13
978-0-323-14739-2 (9780323147392)
Schweitzer Classification
Contributors Preface Contents of Other Volumes1. Ependyma and Subependymal Layer I. Introduction II. Development III. General Histology IV. Regional Differences V. Function References2. Filaments and Tubules in the Nervous System I. Introduction II. Microtubules III. Neurofilaments and Glial Filaments IV. Actin and Myosin in Brain V. Neuropathology of Fibrous Proteins VI. Summary References3. On The Ultrastructure of the Synapse: The Synaptosome as a Morphological Tool I. Introduction II. Definition of Synaptosome III. Comparative Morphology IV. Synaptosomal Fractions V. Correlative Studies VI. Some Applications of Synaptosomal Studies References4. Nonspecific Changes of the Central Nervous System in Normal and Experimental Material I. Introduction II. Abnormalities Incurred during Histologic Preparation III. Alterations Caused by Postmortem Trauma IV. Reactions of Uncertain Origin V. Artifactitious and Nonspecific Changes Encountered in Experimental Material VI. Conclusion References5. The Epiphysis Cerebri I. Introduction II. Structure III. Function IV. Conclusion References6. Molecular Biology of Developing Mammalian Brain I. Growth II. Metabolism of Biopolymers III. Myelination IV. Hormones V. Nutrition VI. Genetic Control of Growth References7. Excitation and Macromolecules-The Squid Giant Axon I. Introduction II. Perfusion Techniques III. Effects of Macromolecular Reagents on Excitability IV. Effects of Physical Chemical Conditions on Excitability V. Optical Effects of Excitation References8. Macromolecules and Excitation I. Introduction II. Bi-Ionic Action Potential III. Reactions of Macromolecules to Calcium Ion IV. Effects of Calcium on the Axon Membrane V. Effects of Proteolytic Enzymes on the Excitable Membrane VI. Effects of Univalent Cations on the Size of the Action Potential VII. Conclusions References9. Dopamine and Its Physiological Significance in Brain Function I. Introduction II. Physiology and Biochemistry of Nigrostriatal Dopamine III. Pharmacology of Striatal Dopamine IV. Nigrostriatal Dopamine and Parkinsonism V. The Striatal Dopamine Deficiency Syndrome-Summary and Conclusions References10. Brain Slices I. Introduction II. General Properties of Cerebral Cortex Slices III. Electrical Properties of Cerebral Cortex Slices IV. Ion Movement V. Transport of Amino Acids VI. Conclusions ReferencesAuthor Index Subject Index