
Information Technology in Bio- and Medical Informatics
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This book constitutes the thoroughly refereed proceedings of the Second International Conference on Information Technology in Bio- and Medical Informatics, ITBAM 2011, held in Toulouse, France, in August/September 2011, in conjunction with DEXA 2011.
The 13 long papers and 5 short papers were carefully selected and address the following topics: decision support and data management in biomedicine; medical data mining and information retrieval; workflow management and decision support in medicine; and classification in bioinformatics. The papers show how broad the spectrum of topics in applications of information technology to biomedical engineering and medical informatics is.
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Content
- Title
- Preface
- Organization
- Table of Contents
- Decision Support and Data Management in Biomedicine
- Exploitation of Translational Bioinformatics for Decision-Making on Cancer Treatments
- Introduction
- Background
- The ONCOdata System
- The OGO System
- Information Exchange between ONCOdata and OGO
- The Approach
- Usage of OGO from other Applications
- Integration in ONCOdata
- Results
- Discussion
- Conclusions
- References
- MedFMI-SiR: A Powerful DBMS Solution for Large-Scale Medical Image Retrieval
- Introduction
- Fundamental Concepts and Related Work
- Content-Based Medical Image Retrieval
- Medical Image Retrieval Systems Combining Textual and Content-Based Information
- DBMS-driven Medical Image Retrieval Approaches
- The MedFMI-SiR System
- MedFMI-SiR Architecture
- DICOM Metadata Management
- Image Feature Vector Generation
- Metadata- and Content-Based Search Integration
- Experimental Evaluation
- Index Creation
- Query Processing
- Conclusion
- References
- Medical Data Mining and Information Retrieval
- Novel Nature Inspired Techniques in Medical Information Retrieval
- Introduction
- Input Dataset Overview
- Nature Inspired Techniques
- Automated Processing
- Expert Intervention
- Results and Conclusion
- References
- Combining Markov Models and Association Analysis for Disease Prediction
- Introduction
- Background Concepts
- Clustering
- Association Analysis
- Markov Models
- A Hybrid Framework for Disease Prediction
- Experimental Results
- Conclusions
- References
- Superiority Real-Time Cardiac Arrhythmias Detection Using Trigger Learning Method
- Introduction
- Related Work
- Arrhythmias Detection Training Dataset
- Arrhythmias Classification Methods
- Trigger Learning Method
- Initial Learning Step
- Checking Usability Step
- Improvement Step
- Re-movement Step
- Experimental Environment
- Results
- Arrhythmias Detection
- Atrial Fibrillation (AF) Detection
- Conclusions
- References
- Monitoring of Physiological Signs Using Telemonitoring System
- Introduction
- Design and Realization
- Conclusion
- References
- Workflow Management and Decision Support in Medicine
- SciProv: An Architecture for Semantic Query in Provenance Metadata on e-Science Context
- Introduction
- Design Considerations for a Metadata Provenance Approach
- Scientific Workflow Provenance System
- SciProv Architecture
- Case Studies
- Conclusion and Future Work
- References
- Integration of Procedural Knowledge in Multi-Agent Systems in Medicine
- Introduction
- Knowledge-Based Home Care eServices
- Home Care Model
- Home Care Structures
- Implementation
- Using Business Processes in Health Care
- Process-Based Multi-Agent System
- Environment Agent
- Execution Agent
- Role Agents
- Process Agent
- Process Director Agent
- Integration of Process-Based Architecture into the K4Care System
- Environment
- Execution Agents
- Role Agents
- Process Agents
- Further Improvements and Discussion
- Conclusions
- References
- A Framework for the Production and Analysis of Hospital Quality Indicators
- Introduction
- Health Indicators
- Administrative Data
- Aim
- Methods
- Results
- Conclusion
- References
- Process Analysis and Reengineering in the Health Sector
- Introduction
- Case Study: The Patient Care Process in the Oncology Division
- Reference
- Classification in Bioinformatics
- Binary Classification Models Comparison: On the Similarity of Datasets and Confusion Matrix for Predictive Toxicology Applications
- Introduction
- Related Work
- Similarity of Toxicology Datasets
- Similarity of Predictive Model Functions
- Similarity of Confusion Matrices
- Similarity of Predictive Models
- Experiments and Results
- Conclusions
- References
- Clustering of Multiple Microarray Experiments Using Information Integration
- Introduction
- Related Work
- Techniques for Clustering of Multiple Microarray Data Sets
- Data
- Cluster Validation Measures
- Estimation of the Number of Clusters
- Results and Discussion
- Conclusion
- References
- Data Mining in Bioinformatics
- A High Performing Tool for Residue Solvent Accessibility Prediction
- Introduction
- Tool Overview
- Fill-up Phase
- Look-Up Phase
- Experiments
- Datasets and Experimental Setup
- Results and Discussion
- Conclusions and Future Work
- References
- Removing Artifacts of Approximated Motifs
- Introduction
- Preliminary Definitions
- Maximality in Conservation versus Measures of Statistical Significance
- Post-processing Filter to Check Maximality in Conservation of Motifs
- Experiments
- Setting Filter Parameters
- Running Time of the Filter
- Conclusions
- References
- A Approach to Clinical Proteomics Data Quality Control and Import
- Introduction
- Data Import Issues
- Problems Related to the Multiplicity of Data Sources
- Problems Related to the Use of Data
- Background
- Ontologies
- Models
- Coupling Ontologies and Models
- Organization of Data Quality Components
- Clinical Data Model Used in the LIMS
- Ontologies
- Mappings
- Ontological Mappings
- Ontology-Schema Mappings
- Implementation of the Approach
- Conclusion
- References
- MAIS-TB: An Integrated Web Tool for Molecular Epidemiology Analysis
- Introduction
- Implementation
- Results and Discussion
- References
- Author Index
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