Cortical Development
Genes and Genetic Abnormalities
1st Edition
Published on 2. August 2008
302 pages
978-0-470-99402-3 (ISBN)
Description
To understand the brain and its devastating diseases, we need toreveal the mechanisms that produce it and the ways in which it canconstantly change throughout a lifetime. This book features atimely and insightful discussion between developmentalneurobiologists and clinicians who deal with disorders of thenervous system.
Chapters in this book deal specifically with cell fatedetermination, cell migration and disorders of cell migration;current concepts and new ideas about cortical arealisation, anddisorders which can arise from incorrect arealisation; genesimplicated in the development of cortical connectivity and relatedpathologies such as schizophrenia and synaesthesia; andsusceptibility genes for cognitive disorders such as schizophrenia,autism, dyslexia, and attention deficit disorder.
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Gregory R. Bock | Jamie A. Goode
Novartis Foundation Symposium 288 - Cortical Development - Genes and Genetic Abnormalities
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02/2008
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The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.
Chair: John Parnavelas, University College London, UK.
Content
Symposium on Cortical development: genes and genetic abnormalities,held at the Novartis Foundation, London, 6-8 February 2007.
Editors: Gregory Bock (Organizer) and Jamie Goode.
This symposium is based on a proposal made by ZoltánMolnár.
John G. Parnavelas Chair's introduction.
Bradley J. Molyneaux, Paola Arlotta and Jeffrey D.Macklis/Molecular development of corticospinal motor neuroncircuitry.
Gordon Fishell /Perspectives on the developmental originsof cortical interneuron diversity.
Pasko Rakic, Kazue Hashimoto-Torii and Matthew R.Sarkisian /Genetic determinants of neuronal migration in thecerebral cortex.
Stephen C. Noctor, Veronica Martinez-Cerdeño andArnold R. Kriegstein /Neural stem and progenitor cells incortical development.
Teresa H. Chae and Christopher A. Walsh /Genesthat control the size of the cerebral cortex.
Vicki Hammond, Joanne Britto, Eva So, Holly Cate andSeong-Seng Tan /Control of cortical neuron layering: lessonsfrom mouse chimeras.
Fujio Murakami, Daisuke Tanaka, Mitsutoshi Yanagida andEmi Yamazaki /Intracortical multidirectional migration ofcortical interneurons.
Libing Zhou, Fadel Tissir and André M.Goffinet /The atypical cadherin Celsr3 regulates thedevelopment of the axonal blueprint.
Dennis D. M. O'Leary , Shen-Ju Chou, TadashiHamasaki, Setsuko Sahara, Akihide Takeuchi, SandrineThuret and Axel Leingärtner /Regulation of laminarand area patterning of mammalian neocortex and behaviouralimplications.
Jeremy A. Cholfin and John L. R. Rubenstein/Genetic regulation of prefrontal cortex development andfunction.
Henry Kennedy, Rodney Douglas, Kenneth Knoblauch andColette Dehay /Self-organization and pattern formation inprimate cortical networks.
Nobuhiko Yamamoto, Takuro Maruyama, Naofumi Uesaka,Yasufumi Hayano, Makoto Takemoto and Akito Yamada/Molecular mechanisms of thalamocortical axon targeting.
Zoltán Molnár, Anna Hoerder-Suabedissen, Wei ZhiWang, Jamin DeProto, Kay Davies, Sheena Lee, Erin C.Jacobs, Anthony T. Campagnoni, Ole Paulsen, Maria CarmenPiñon and Amanda F. P. Cheung /Genes involved inthe formation of the earliest cortical circuits.
Michael Piper, Amber-Lee S. Dawson, Charlotta Lindwall, GuyBarry, Céline Plachez and Linda J. Richards/Emx and Nfi genes regulate cortical development andaxon guidance in the telencephalon.
Paul J. Harrison /Schizophrenia susceptibility genes andtheir neurodevelopmental implications: focus on neuregulin.
Peter B. Crino /Focal brain malformations: a spectrum ofdisorders along the mTOR cascade.
Index of contributors.
Subject Index.
