Untranslated Gene Regions and Other Non-coding Elements
Regulation of Eukaryotic Gene Expression
1st Edition
Published on 26. June 2013
VIII, 56 pages
978-3-0348-0679-4 (ISBN)
Description
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as "junk DNA", it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5' and 3' untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.
More details
Series
Language
English
Place of publication
Basel
Switzerland
Publishing group
Springer Basel
Target group
Professional and scholarly
Product notice
Reflowable
Illustrations
VIII, 56 p. 2 illus. in color.
File size
2,58 MB
ISBN-13
978-3-0348-0679-4 (9783034806794)
DOI
10.1007/978-3-0348-0679-4
Schweitzer Classification
Other editions
Additional editions
Lucy W. Barrett | Sue Fletcher | Steve D. Wilton
Untranslated Gene Regions and Other Non-coding Elements
Regulation of Eukaryotic Gene Expression
Book
07/2013
Springer
€53.49
Shipment within 10-15 days
Content
Introduction.- Promoter.- 5' Untranslated Region.- Structure.- Intronic Regions.- 3' Untranslated Region.- Non-coding RNAs.- Conclusion.
