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Brainstem Control of Spinal Cord Function summarizes the research findings on major bulbospinal control systems. It explores how sensory, reflex-evoking inputs to the central nervous system (CNS) modulate descending control signals and how descending control signals regulate the excitability or gains of the segmental reflex arcs. It also looks at the role of the reticulospinal system in the control of movement, the effects of labyrinth and neck inputs on vestibulospinal and medullary reticulospinal neurons, the behavioral significance of the raphe-spinal system, locus coeruleus control of spinal cord activity, and the influence of allergic encephalomyelitis on monoaminergic neurotransmission. Organized into six chapters, this book begins with an overview of the findings on how human spinal reflexes are modulated. It then discusses the reticulospinal system, its role in the control of movements, and its involvement in responses elicited from several sensory systems. In addition, the book examines the response characteristics of the vestibulospinal and the medullary reticulospinal systems based on experiments on labyrinthine and neck input. Other chapters focus on all aspects, including motor and sensory, of the raphe-spinal system, physiological aspects of coerulospinal neurons, and the mechanisms by which allergic encephalomyelitis results in hindlimb paralysis. This book is a valuable resource for physiologists and students of physiology.
Language
Place of publication
Publishing group
Elsevier Science & Techn.
ISBN-13
978-0-323-15677-6 (9780323156776)
Schweitzer Classification
Contributors Preface1. Modulation of Human Spinal Reflexes I. Introduction II. Methods for Observing Human Reflex Responses III. Responses at the Ankle, Wrist, and Elbow Joints IV. Modulation of the Electromyographic Response V. Reflex Contributions to Motor Behavior VI. Summary and Conclusions References 2. The Reticulospinal System and Its Role in the Control of Movement I. Introduction II . Anatomy of Reticulospinal Systems III. Reticulomotor Connections IV. Reticulospinal Role in Vestibular Reflexes V. Reticulospinal Role in Tectal Orienting Responses VI. Reticulospinal Role in Responses Evoked by Activation of Somatic Afférents VII. Cerebral and Cerebellar Action on Reticulospinal Neurons VIII. Conclusions References3. A Comparison of the Response Characteristics of Vestibulospinal and Medullary Reticulospinal Neurons to Labyrinth and Neck Inputs I. Introduction II. Experimental Procedures III. Results IV. Discussion V. Summary References 4. The Raphe-Spinal System Abbreviations I. Introduction II. Anatomy III. Physiology IV. Behavioral Significance of Raphe-Spinal System V. Conclusions References5. Locus Coeruleus Control of Spinal Cord Activity I. Introduction II. Historical Perspectives III. Anatomy IV. Physiology V. Methodology VI. Results and Discussion References6. Experimental Allergic Encephalomyelitis: Effects on Monoaminergic Neurotransmission I. Introduction II. Neurophysiological Basis of Clinical Signs III. Summary and Conclusions ReferencesIndex