Current Topics in Membranes and Transport
Published on 30. June 1984
575 pages
978-0-08-058493-5 (ISBN)
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Current Topics in Membranes and Transport
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Felix Bronner | A. Kleinzeller
Current Topics in Membranes and Transport: v. 22
Book
06/1984
Academic Press
€69.33
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Content
- Front Cover
- The Squid Axon
- Copyright Page
- Contents
- Contributors
- Preface
- Yale Membrane Transport Processes Volumes
- PART I: STRUCTURE
- Chapter 1. Squid Axon Ultrastructure
- l. Introduction
- ll. Anatomical Organization
- lll. Histological Organization
- IV. Fine Structure
- V. Nerve Fractions
- VI. Concluding Remarks
- References
- Chapter 2. The Structure of Axoplasm
- I. Introduction
- ll. Fine Structure of the Squid Giant Axon
- lll. Axonal Transport in the Squid Giant Axon
- IV. Extruded Axoplasm from the Giant Axon
- V. Conclusions
- References
- PART II: REGULATION OF THE AXOPLASMIC ENVIRONMENT
- Chapter 3. Biochemistry and Metabolism of the Squid Giant Axon
- I. Introduction
- ll. Molecular Composition of Axoplasm
- lll. Functional Metabolic Studies Using the Giant Axon System
- IV. Concluding Remarks
- References
- Chapter 4. Transport of Sugars and Amino Acids
- I. Introduction
- ll. Concentration and State of Sugars and Amino Acids in Axoplasm
- Ill. Transport of Sugars by Squid Axons
- IV. Descriptive Models for Sugar Transport
- V. Transport of Amino Acids
- VI. General Conclusions
- References
- Chapter 5. Sodium Pump in Squid Axons
- I. Introduction
- ll. Experimental Techniques
- lll. Sodium Pump in Squid Axons
- References
- Chapter 6. Chloride in the Squid Giant Axon
- I. Introduction
- ll. [CI-] in Axoplasm and Hemolymph
- lll. Transmembrane CI- Movements
- IV. Summary and Discussion
- References
- Chapter 7. Axonai Calcium and Magnesium Homeostasis
- I. Introduction
- ll. Axonal Ca and Mg: The Problem of Bound versus Free
- Ill. Axonal Mg Homeostasis
- IV. Axonal Ca Homeostasis
- References
- Chapter 8. Regulation of Axonal pH
- I. Introduction
- ll. Methodology
- lll. Effect of Weak Bases and Acids on pHi
- IV. Effect of Metabolic Inhibitors on pHi
- V. Ionic Mechanism of pHi Regulation
- References
- Chapter 9. Hormone-Sensitive Cyclic Nucleotide Metabolism in Giant Axons of Loligo
- I. Introduction
- ll. Cyclic AMP Levels in Intact Axons
- lll. CAMP Production and Breakdown in Perfused Axons
- lV. Conclusion
- References
- PART III: EXCITABILITY
- Chapter 10. Hodgkin-Huxley: Thirty Years After
- I. Introduction
- ll. Action Potential
- lll. Voltage-Clamp Currents
- IV. Hodgkin-Huxley Analysis
- V. Reconstruction of the Electrical Behavior of the Squid Axon from the Hodgkin-Huxley Equations
- VI. Molecular Properties of the Na Channel: Permeability Ratios and Binding Constants
- VII. Concluding Remarks
- References
- Chapter 11. Sequential Models of Sodium Channel Gating
- l. Introduction
- ll. Results
- lll. Discussion
- References
- Chapter 13. Multi-Ion Nature of Potassium Channels in Squid Axons
- I. Introduction
- ll. Characteristics of Multi-Ion Pores
- lll. Experimental Results
- IV. A Mathematical Model
- V. More on Energy Barriers
- VI. Summary and Conclusions
- References
- Chapter 14. Noise Analysis and Single-Channel Recordings
- I. Introduction
- ll. Basic Concepts of Fluctuation Analysis
- lll. The Physical Basis of Membrane Noise
- lV. Channel Noise in Nerve Membranes
- V. Single-Channel Recordings
- References
- Chapter 15. Membrane Surface Charge
- I. Introduction
- ll. Channel Surface-Charge Density: Theory
- Ill. Neutralization of Channel Surface-Charge Density
- lV. Relation of Average Surface-Charge Density to Channel Surface-Charge Density
- V. Modifications of Surface Charge
- VI. Significance
- Vll. Summary
- References
- Chapter 16. Optical Signals: Changes in Membrane Structure, Recording of Membrane Potential, and Measurement of Calcium
- l. Introduction
- ll. Intrinsic Signals
- lll. Dye Measurements of Membrane Potential
- IV. Measurement of Changes in Internal Calcium Concentration
- V. Conclusions
- References
- Chapter 17. Effects of Anesthetics on the Squid Giant Axon
- I. Introduction
- ll. Effects of Anesthetics on the Action Potential and Sodium and Potassium Currents of the Squid Giant Axon
- lll. Mechanisms of Sodium and Potassium Current Suppression
- References
- Chapter 18. Pharmacology of Nerve Membrane Sodium Channels
- I. Introduction
- ll. Ionic-Channel Block by Chemicals
- lll. Ionic-Channel Modulation by Chemicals
- IV. Conclusions
- References
- PART IV: INTERACTION BETWEEN GIANT AXON AND NEIGHBORING CELLS
- Chapter 19. The Squid Giant Synapse
- I. Introduction
- ll. Anatomy
- lll. Early Electrophysiology
- IV. Synaptic Transmission without Action Potentials
- V. Electrophysiological Properties of the Postsynaptic Potential
- VI. Voltage Clamp of the Presynaptic Element Using Square Pulses
- Vll. Voltage Clamp with Action Potential Waveform
- References
- Chapter 20. Axon-Schwann Cell Relationship
- I. Introduction
- lI. Axon-Schwann Cell Interface
- lll. Axon-Schwann Cell Signaling
- IV. Schwann Cell Responses
- V. Cell-to-Cell Communication
- VI. Concluding Remarks
- References
- Index
- Contents of Previous Volumes
