CELL BIOLOGY, BIOCHEMICAL AND MOLECULAR TECHNOLOGIES Cell Biology of Hyphae, O. Yarden Protoplast Isolation, Regeneration, and Fusion in Filamentous Fungi, S.P. Kale and D. Bhatnagar Metabolic Pathway Regulation, P.-K. Chang and R.B. Todd Fungal Nuclei and Chromosomes, B.C.K. Lu Genomics of Filamentous Fungi: A General Review, A.M. Fakhoury and G.A. Payne Stability and Instability of Fungal Genomes, A.J. Clutterbuck Secondary Metabolic Gene Clusters in Filamentous Fungi, J.W. Cary Application of Gene Cloning in Fungal Biotechnology, L. Hornok and G. Giczey Transformation and Gene Manipulation in Filamentous Fungi: An Overview, R.L. Mach Genetic Manipulation Systems for Nonconventional Fungi, J.W Wostemeyer, A. Burmester, and C. Schimek Fungal Mitochondria: Genomes, Genetic Elements, and Gene Expression, J.C. Kennell and S.M. Cohen Fungal Evolution Meets Fungal Genomics, J. Leigh, E. Seif, N. Rodriguez-Ezpeleta, Y. Jacob, and B.F. Lang Genome Sequence Patterns and Gene Regulation: A Bioinformatics Perspective, G.B. Singh DNA Chips and Microarray Analysis: An Overview, S. Choi Signal Transduction in Fungi: Signaling Cascades Regulating Virulence in Filamentous Fungi, S. Zeilinger COMMERCIAL APPLICATIONS AND BIOTECHNOLOGICAL POTENTIAL Application of Genetic Engineering for Strain Improvement in Filamentous Fungi, H. Nevalainen, V. Te 'o, and M. Penttila The Genetic Improvement of Wine Yeasts, I.S. Pretorius Fungi in Brewing: Biodiversity and Biotechnology Perspectives, J. Hansen and J. Piskur Ethanol-Tolerance and Production by Yeast, T. Benitez and A. C. Codon Solid-State Fermentation: An Overview, P. Nigam, T. Robinson, and D. Singh Basic Principles for the Production of Fungal Enzymes by Solid-State Fermentation, G. Viniegra-Gonzalez and E. Favela-Torres Commercial Importance of Some Fungal Enzymes, R. K. Saxsena, B. Malhotra, and A. Batra Xylanases of Thermophilic Molds and Their Application Potential, S. Rawat and B.N. Johri Chitin Biosynthesis in Fungi, J. Ruiz-Herrera and R. Ruiz-Medrano Bioactive Fungal Polysaccharides and Polysaccharopeptides, T.B. Ng Biotechnological Potential of Fungal Lipids, M. Sancholle, F. Laruelle, D.M.L Losel,and J. Muchembled Introduction to the Theory of Metabolic Modeling and Optimization of Biochemical Systems: Application to Citric Acid Production in Aspergillus niger, N.V. Torres, F. Alvarez-Vasquez, and E.O. Voit Fungal Carotenoid Production, J. Avalos and E. Cerda-Olmedo Fungal Terpenoid Antibiotics and Enzyme Inhibitors, S. Inouye, S. Abe, and H. Yamaguchi Commercial Production and Biosynthesis of Fungal Antibiotics: An Overview, S. Gutieerrez, R.E. Cardoza, J. Casqueiro, and J.F. Martin Molecular Biology of Trichoderma and Biotechological Applications, M. Pentilla, C. Limon, and H. Nevalainen Plectomycetes:Biotechnological Importance and Systematics, J. Sugiyama and H. Ogawa Exploitation of GFP-Technology with Filamentous Fungi, D.F. Jensen and A. Schulz MEDICAL BIOTECHNOLOGY Antifungal Drugs in Fungal Infections, Y. Niwano Antitumor and Immunomodulatory Compounds from Fungi, T.B. Ng Clinical and Laboratory Diagnosis of Fungal Infections, M. Richardson and S. Nikkari Candidiasis, A.G. Palma-Carlos and M.L. Palma-Carlos Immunizations Against Fungal Diseases in Man and Animals, E. Segal and D. Elad Fungal Allergy, V.P. Kurup CULTURE COLLECTIONS AND BIOSAFETY Current Status of Fungal Collections and Their Role in Biotechnology, D. Smith and M.J. Ryan Benefits and Risks of Genetically Modified Foods: An Overview, F. Goodyear-Smith Transgenic Mycoherbicides:Needs and Safety Considerations, J. Gressel Recent Developments in Biotechnology and Intellectual Property, Access to Genetic Resources, and Benefit-Sharing, P. Cheyne Index