Lipid Droplets
Published on 28. December 2018
214 pages
978-1-5361-4577-9 (ISBN)
Description
The topics analyzed cover a broad spectrum of lipid droplets and presents new information in this area of research. The themes analyzed include: Lipid droplets as potential antiviral targets; lipid droplets during embryonic development; lipid droplets and their contribution to vldl and chylomicron maturation; important advances in the knowledge of lipid droplets in the last six decades; lipid droplets: structure, composition, formation and function, connection with the endoplasmic reticulum, signaling of lipid droplet metabolism by tor and ampk pathways; and lipid droplets and the pathophysiology of liver diseases.
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Angel Catala
Lipid Droplets
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01/2019
Nova Science Publishers Inc
€172.60
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Content
- Intro
- Contents
- Preface
- Chapter 1
- Lipid Droplets as Potential Antiviral Targets for Flaviviruses
- Abstract
- Introduction
- Dengue, Zika and Yellow Fever Viruses
- Lipid Metabolism in DENV Infection
- Lipid Droplets and DENV Infections
- Materials and Methods
- Cells and Viruses
- Microarray Analysis of DENV-2-Infected HepG2 Cells
- Immunofluorescence
- Lipid Droplet Counting
- Statistical Analysis
- Results
- Conclusion
- References
- Chapter 2
- Lipid Droplets and Embryonic Development
- Abstract
- 1. Introduction
- 2. Basic Composition and Turnover of the Lipid Droplets
- 3. Lipid Droplets in Cells
- 4. Lipid Droplets in Different Organisms
- 5. LDs in Embryonic Development
- 5.1. LDs in Oviparous Embryos
- 5.2. LDs in Viviparous Embryos (Mammalian Embryos)
- Conclusion
- References
- Chapter 3
- Lipid Droplets and Their Contribution to Chylomicron and VLDL Maturation
- Abstract
- Introduction
- Formation of Lipid Droplets (LDs)
- Formation of Chylomicrons (CMs)
- Formation of Very Low Density Lipoproteins (VLDLs)
- References
- Chapter 4
- Important Advances in the Knowledge of Lipid Droplets in the Last Six Decades
- Abstract
- Introduction
- The Significance of Lipid Droplets in Biological Systems
- J Biophys Biochem Cytol. 1959 Dec
- 6: 427-430.
- J Cell Biol. 1964 May
- 21: 233-244.
- J Cell Biol. 1967 May
- 33(2):319-339.
- J Clin Invest. 1970 Aug
- 49(8):1479-1988.
- J Lipid Res. 1970 Sep
- 11(5): 420-432.
- Biochem J. 1973 Feb
- 132(2):323-327.
- J Cell Biol. 1974 Nov
- 63(2 Pt 1): 683-691.
- Exp Pathol (Jena). 1979
- 17 (4):208-214.
- Experiential. 1979 Aug 15
- 35(8):1075-1076.
- J Anat. 1979 Sep
- 129(Pt 2): 423-426.
- Atherosclerosis. 1980 Sep
- 37(1):139-142.
- Cell Tissue Res. 1981
- 216(3): 661-663.
- Atherosclerosis. 1981 Nov-Dec
- 40(3-4): 223-230.
- Cancer Res. 1982 Jul
- 42(7): 2715-2721.
- Biol Neonate. 1983
- 43(1-2):92-102.
- J Biochem. 1983 Feb
- 93(2):575-582.
- Cell Structure Funct. 1983 Mar
- 8(1): 35-42.
- FEBS Lett. 1983 Apr 5
- 154(1):211-213.
- Biochim Biophys Acta. 1983 Nov 29
- 754(2):159-165.
- Anat Rec. 1984 Nov
- 210(3):415-20.
- J Cell Biol. 1985 Mar
- 100(3):965-373.
- Cell Biol Int Rep. 1985 Jul
- 9(7): 613-618.
- J Lipid Res. 1985 Jul
- 26(7):781-789.
- J Lipid Res. 1986 Oct
- 27(10):1097-1103.
- J Lipid Res. 1986 Nov
- 27(11):1174-1181.
- Acta Histochem. 1987
- 82 (2):149-152.
- Arteriosclerosis. 1987 Mar-Apr
- 7(2):185-190.
- Brain Res. 1987 Mar 17
- 4 06(1-2): 215-223.
- J Histochem Cytochem. 1988 Oct
- 36(10):1319-1328.
- J Lipid Res. 1988 Nov
- 29 (11):1523-1534.
- J Ultrastruct Mol Struct Res. 1989 Apr
- 102(1): 87-94.
- Heart Vessels Suppl. 1990
- 5: 55-58.
- Am J Pathol. 1989 Mar
- 134(3): 705-717.
- J Lipid Res. 1988 Nov
- 29 (11):1523-1534.
- J Histochem Cytochem. 1988 Oct
- 36(10):1319-1328.
- Biochemistry 1987 Sep 8
- 26(18):5820-5825.
- Biochem Soc Trans. 1995 (3):611-5.
- Trends Biochem Sci. 1999 (3):109-15.
- Semin Cell Dev Biol. 1999 (1):51-8.
- Trends Biochem Sci. 2000 (8):357-62.
- Curr Biol. 2001
- 11(11):R446-9.
- Semin Cell Dev Biol. 2005 (2):163-74.
- Ann N Y Acad Sci. 2006
- 1086: 104-15.
- FEBS Lett. 2006
- 580(23):5484-91.
- Nat Rev Mol Cell Biol. 2006
- 7(5):373-8.
- Endocrinology. 2008
- 149(3):942-9.
- J Lipid Res. 2009 50 Suppl: S329-34.
- Curr Hypertens Rep. 2008
- 10(6):461-6.
- Biochim Biophys Acta. 2009
- 1791(6):399-407.
- Biochim Biophys Acta. 2009
- 1791(6):448-58.
- Biochim Biophys Acta. 2009
- 1791(6):441-7.
- Prog Lipid Res. 2009
- 48(3-4):191-5.
- J Lipid Res. 2010
- 51(2):262-73.
- FEBS Lett. 2010
- 584(11):2168-75.
- FEBS Lett. 2010
- 584(11):2176-82.
- J Biol Chem. 2012
- 287(4):2280-7.
- J Lipid Res. 2012
- 53(1):28-33.
- J Lipid Res. 2012
- 53(2):215-26.
- Protoplasma. 2012
- 249(3):541-85.
- Annu Rev Biochem. 2012
- 81:687-71
- Curr Opin Lipidol. 2013
- 24(2):160-70.
- Biochim Biophys Acta. 2013 Mar
- 1831(3):589-94.
- Chem Biol. 2014
- 21(1):86-96.
- Crit Rev Biochem Mol Biol. 2014
- 49(4):304-26.
- Curr Opin Cell Biol. 2015
- 33:119-24.
- Biochimie. 2016 Jan
- 120:17-27.
- Annu Rev Nutr. 2016
- 36:471-509.
- Biochim Biophys Acta. 2017
- 1859(9 Pt B):1583-1595.
- Biochim Biophys Acta. 2017
- 1864(9):1459-1468.
- Cell Metab. 2018 Apr 3
- 27(4): 869-885.
- Adipocyte 2018 Apr 5: 1-5.
- Int rev cell mol biol. 2018
- 337: 83-110.
- J Lipid Res. 2018 Apr 5. pii: jlr.D085217. doi: 10.1194/jlr.D085217. [Epub ahead of print]
- Plant Physiol. 2018 Mar
- 176(3):1894-1918. doi: 10.1104/pp.17.01677. Epub 2017 Dec 21.
- Chapter 5
- Lipid Droplets: Structure, Composition, Formation and Function. Connection with the Endoplasmic Reticulum
- Abstract
- Introduction
- Structure, Composition, Formation and Function of Lipid Droplets
- Structure and Composition of Lipid Droplets
- Lipids
- Proteins
- Formation of Lipid Droplets
- Function of Lipid Droplets
- Lipid peroxidation and Lipid Droplets
- Conclusion
- References
- Chapter 6
- Signaling of Lipid Droplet Metabolism by TOR and AMPK Pathways
- Introduction
- Neutral Lipid Synthesis
- TOR Pathway and the Regulation of Lipid Droplets
- AMPK and the Regulation of Lipid Droplets
- Crosstalk between AMPK and TOR Pathways
- References
- Chapter 7
- Lipid Droplets and the Pathophysiology of Liver Diseases
- Abstract
- Introduction
- LD Composition
- LD Biogenesis
- Mobilization of Lipids from LDs
- LD Proteins in HCV Infection
- Roles of LD Proteins in Nonalcoholic Fatty Liver disease (NAFLD)
- Role of LD Proteins in Nonalcoholic Steatohepatitis (NASH)
- Role of LLDs in the Development of Liver Disease
- Conclusion
- Conflict of Interest Statement
- Acknowledgments
- References
- About the Editor
- Index
- Blank Page
- Blank Page
