Advances in Virus Research
Academic Press
Published on 14. August 2002
339 pages
978-0-08-052244-9 (ISBN)
Description
This latest volume in the Advances in Virus Research series presents articles on topics such as the role of lipid rafts in virus assembly and budding; novel vaccine strategies; treatment of arenavirus infections; the evaluation of drug resistance in HIV infection; perspectives on polydnavirus origin and evolution; bateriophage 29 DNA packaging; the potential of plant viral vectors and transgenic plants for subunit vaccine production; and the interaction of orthopoxviruses with interferon-treated cultured cells. This timely and informative compilation of articles will be of interest to researchers in the fields of virology, immunology, microbiology, and plant science.
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Aaron J. Shatkin | Frederick A. Murphy | Karl Maramorosch
Advances in Virus Research: Volume 58
Book
08/2002
Academic Press
€142.37
Withdrawn from sale
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Content
- Front Cover
- Advances in Virus Research
- Copyright Page
- Contents
- Chapter 1. Role of Lipid Rafts in Virus Assembly and Budding
- I. Introduction
- II. Lipid Rafts
- III. Functions of Lipid Rafts
- IV. Assembly of Influenza Virus
- V. Conclusion
- References
- Chapter 2. Novel Vaccine Strategies
- I. Introduction
- II. The Ideal Vaccine
- III. Principles of Vaccination
- IV. Conventional Vaccines
- V. Genetically Engineered Vaccines
- VI. Marker Vaccines
- VII. Vaccine Formulation and Delivery
- VIII. Epilogue
- References
- Chapter 3. The Potential of Plant Viral Vectors and Transgenic Plants for Subunit Vaccine Production
- I. Current Trends in Vaccine Development
- II. An Overview: The Use of Plants for Recombinant Protein Expression
- III. Plant Protein-Expression Systems
- IV. Stable Transgenic Expression Systems
- V. Plant Virus Expression Systems
- VI. Enhancing Protein Yield
- VII. Expression of Immunogenic Molecules
- VIII. Immunogenicity and Vaccine Responses
- IX. Edible Vaccines and Human Health
- X. Conclusion
- References
- Chapter 4. Treatment of Arenavirus Infections: From Basic Studies to the Challenge of Antiviral Therapy
- I. Introduction
- II. Classification
- III. Arenaviruses as Agents of Emerging Diseases
- IV. The Virus
- V. Virus Infection and the Host Cell
- VI. The Replicative Cycle and Possible Targets for Therapeutic Agents
- VII. Present Treatment of Human Disease
- VIII. Concluding Remarks
- References
- Chapter 5. Evaluation of Drug Resistance in HIV Infection
- I. Introduction
- II. Targets of Antiviral Drug Therapy in HIV Infection
- III. Mechanisms of Antiviral Drug Resistance
- IV. Technologies for Measuring Drug Sensitivity
- V. Clinical Implications
- VI. Conclusions
- References
- Chapter 6. Perspectives on Polydnavirus Origins and Evolution
- I. Introduction
- II. Classification of Polydnaviruses as Viruses
- III. Ichnoviruses
- IV. Bracoviruses
- V. Origin of the Polydnaviridae
- VI. Conclusion
- References
- Chapter 7. Bacteriophage phi 29 DNA Packaging
- I. Introduction
- II. Overview of phi 29 DNA Packaging
- III. Components of the Defined phi 29 DNA Packaging System
- IV. The DNA Packaging Process
- V. Aims and Prospects
- References
- Chapter 8. The Interaction of Orthopoxviruses and Interferon-Treated Cultured Cells
- I. Introduction
- II. Interaction of Poxviruses with the IFN Type I-Treated Host Cell
- III. The Posttranscriptional Inhibition of Poxvirus-Specific Gene Expression in IFN Type I-Treated Chick Embryo Fibroblasts
- IV. Cytotoxicity Enhancement of IFN Type I-Treated and Vaccinia Virus-Infected Cells
- V. Inhibition of Vaccinia Virus Replication by Nitric Oxide Synthase Induced by IFN Type II
- VI. Metabolic Activities Are Required for the Response of the IFN Type I-Treated Host Cell to Vaccinia Virus Infection
- VII. Double-Stranded RNA Molecules Detectable during Vaccinia Virus Replication and Their Role in the Interaction of Vaccinia Virus with the IFN Type I-Treated Host Cell
- VIII. Modulation of the Cellular IFN Type I and Type II Responses by Poxvirus-Speci.c Gene Products
- IX. Concluding Remarks
- References
- Index
