
Advances in Protein Chemistry
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Content
- Front Cover
- Advances in Protein Chemistry, Volume 38
- Copyright Page
- Contents
- Chapter 1. Regulatory and Cytoskeletal Proteins of Vertebrate Skeletal Muscle
- I. Introductory Remarks
- II. Calcium Regulatory Proteins: Troponin and Tropomyosin
- III. Connectin (Titin)
- References
- Chapter 2. Mechanistic Aspects of DNA Topoisomerases
- I. Introduction
- II. The Reactions of Topoisomerases
- III. DNA Binding
- IV. DNA Cleavage
- V. DNA Reunion
- VI. ATP Hydrolysis
- VII. Processivity in Topoisomerase Reactions
- VIII. Covalent Modification of Topoisomerases
- IX. Mechanistic Models
- X. Concluding Remarks
- References
- Chapter 3. Molecular Mechanisms of Protein Secretion: The Role of the Signal Sequence
- I. Introduction
- II. Historical Background
- III. The Signal Sequence
- IV. Components of the Secretory Apparatus
- V. How Does Secretion Occur?
- VI. What Are the Roles of the Signal Sequence?
- VII. Recapitulation
- VIII. A Model for the Initial Interactions of Signal Sequences with the Membrane
- IX. Signal Sequences as Membrane-Interacting Sequences
- References
- Chapter 4. Vibrational Spectroscopy and Conformation of Peptides, Polypeptides, and Proteins
- I. Introduction
- II. Theoretical Considerations
- III. Extended Polypeptide Chain Structures
- IV. Helical Polypeptide Chain Structures
- V. Reverse Turns
- VI. Characteristics of Polypeptide Chain Modes
- VII. Vibrational Spectroscopy of Proteins
- VIII. Prospects for the Future
- References
- Author Index
- Subject Index
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