Advances in Protein Chemistry
Academic Press
Published on 3. November 1978
338 pages
978-0-08-058205-4 (ISBN)
Description
Advances in Protein Chemistry
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Advances in Protein Chemistry: v. 32
Book
11/1978
Academic Press
€94.87
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Content
- Front Cover
- Advances in Protein Chemistry, Volume 32
- Copyright Page
- Contents
- Contributors to Volume 32
- Chapter 1. The Structural Basis of Antibody Complementarity
- I. Introduction
- II. Immunochemical Studies of the Size and Shape of Antibody Combining Sites
- III. Fragments, Chains, and Domains of Immunoglobulins and Antibodies
- IV. The Recognition and Role of Variable Regions
- V. Hypervariable Regions or Complementarity- Determining Segments (CDR)
- VI. Correlation of Variability with Physiochemical Properties of Amino Acids in Immunoglobulin Chains
- VII. Affinity Labeling Data and Hypervariable Segments
- VIII. X-Ray Crystallographic Studies on the Combining Sites of Myeloma Proteins
- IX. Predictive Attempts Based on Inserting CDR Sequences upon a Constant Framework
- X. Predictive Attempts Based on Statistical Examinations of Sequences and Distribution of Amino Acids in CDR
- XI. Other Directions
- References
- Chapter 2. Protein Fractionation at Subzero Temperatures
- I. Introduction
- II. The Properties of Aqueous-Organic Mixtures as a Function of Temperature: Physiochemical Data and Their Manipulation
- III. Adaptation of Fractionation Techniques to Subzero Temperatures
- IV. Applications
- V. Conclusions
- Addendum
- References
- Chapter 3. Antifreeze Protein from Fish Bloods
- I. Introduction
- II. Freezing Resistances of Polar Fish Blood Sera
- III. Preparation and Properties of Antifreeze Glycoprotein (AFGP) from Antarctic Fish Bloods
- IV. The Antilectin Activity of AFGP
- V. Effects of AFGP on Freezing
- VI. Activities of Chemical Derivatives of AFGP
- VII. Other Proteins Reported To Have Antifreeze Activity
- VIII. Theoretical Aspects of Actions of Substances Lowering Freezing Temperatures
- IX. Discussions of Models for Mechanism of Action of Antifreeze Systems
- X. Summary and Conclusions
- References
- Note Added in Proof
- Chapter 4. Proteins at Interfaces
- I. Introduction
- II. Experimental Techniques
- III. Kinetics and Mechanism of Adsorption
- IV. Conformation of Protein Molecules at Interfaces
- V. Equilibrium Aspects of Adsorption
- VI. Reactions at Interfaces
- VII. Proteins at Interfaces in Biological Systems
- References
- Author Index
- Subject Index
- Contents of Previous Volumes
