Advances in Protein Chemistry
Academic Press
Published on 31. March 1970
571 pages
978-0-08-058197-2 (ISBN)
Description
Advances in Protein Chemistry
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Advances in Protein Chemistry: v. 24
Book
04/1970
Academic Press
€87.90
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Content
- Front Cover
- Advances in Protein Chemistry, Volume 24
- Copyright Page
- Contents
- Contributors to Volume 24
- Mortimer Louis Anson
- Contents of Previous Volumes
- Chapter 1. Protein Denaturation Part C. Theoretical Models for the Mechanism of Denaturation
- I. Introduction
- II. General Equations for Equilibria between Native and Denatured States
- III. Thermodynamic Data from the Study of Model Compounds
- IV. Principal Denatured States and the Conditions under Which They Are Stable
- V. Thermodynamics of Transition from Native to Denatured States
- VI. Binding Sites for Denaturants
- VII. Kinetics of Denaturation
- VIII. Equilibria and Rates under Native Conditions. Relation to Hydrogen Exchange
- IX. Relation between Denaturation and the "Structure" of Water
- X. Older Theoretical Models
- References
- Chapter 2. Selective Cleavage and Modification of Peptides and Proteins
- I. Introduction
- II. Classification of Chemical Cleavages
- III. Cleavage at the a-Carbon
- IV. Conversion of Serine to Cysteine
- V. Cleavage of the "N-Peptide" Bond
- VI. Cleavage of Aspartyl and Glutamyl Residues (Both "N-" and "C-Peptide" Cleavage)
- VII. Cleavage of the "C-Peptide" Bond
- VIII. Photochemical Alkylation of Glycine
- IX. Selective Peptide Cleavage Mediated by Metal Ions
- X. Creation of New Sites for Chemical or Enzymatic Cleavage
- XI. Modifications Blocking Chemical or Enzymatic Cleavage
- XII. Chemical Reactivity and Tertiary Structure
- Notes Added in Proof
- References
- Chapter 3. Recent Developments in Chemical Modification and Sequential Degradation of Proteins
- I. Chemical Modification
- II. Sequential Degradation
- References
- Chapter 4. Partition of Cell Particles and Macromolecules in Polymer Two-Phase Systems
- I. Introduction
- II. Polymer Two-Phase Systems
- III. General Partition Behavior of Macromolecules and Particles
- IV. Adsorption at the Interface
- V. Countercurrent Distribution
- VI. Removal of Polymers
- VII. Applications
- VIII. Discussion and Conclusions
- References
- Chapter 5. Analytical Gel Chromatography of Proteins
- I. Introduction
- II. General Aspects of Solute Partitioning in Porous Networks
- III. Theory of Column Operation
- IV. Determination of Molecular Size and Weight
- V. Nonelution Methods
- VI. Studies of Multicomponent Systems
- VII. Concluding Remarks
- References
- Chapter 6. Nuclear Magnetic Resonance Spectroscopy of Amino Acids, Peptides, and Proteins
- I. Introduction
- II. NMR of Amino Acids
- III. NMR of Peptides
- IV. NMR of Polypeptides and the Helix-Coil Transition
- V. NMR of Proteins
- VI. Concluding Remarks
- Appendix: Basic Concepts
- References
- AUTHOR INDEX
- SUBJECT ENDEX
