
Advances in Protein Chemistry
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Content
- Front Cover
- Advances in Protein Chemistry, Volume 23
- Copyright Page
- Contents
- Contributors to Volumes 23
- Preface
- Contents of Previous Volumes
- Errata for Volume 22
- Chapter 1. Relaxation Spectrometry of Biological Systems
- I. Introduction
- II. Theory of Relaxation Spectrometry
- III. Experimental Methods
- IV. Application of Relaxation Methods to Biological Systems
- V. Prognosis
- References
- Chapter 2. The Preparation of Isomorphous Derivatives
- I. Introduction
- II. Protein Crystallography
- III. General Experimental Methods
- IV. Heavy-Atom Derivatives
- V. Light-Atom Derivatives
- References
- Chapter 3. Protein Denaturation
- Part A. Characterization of the Denatured State
- I. Introduction
- II. Methods for Characterization
- III. Experimental Results for the Products Obtained by Various Modes of Denaturation
- Part B. The Transition from Native to Denatured State
- I. Reversibility
- II. Intermediate States between Native and Denatured Forms
- III. Thermodynamic Characterization of Two-State Processes Leading to Disordered Products
- IV. Thermodynamics of Denaturation by Acid pH
- V. "Phase Diagrams" for Conformational States
- VI. Kinetics of Denaturation
- References for Parts A and B
- Chapter 4. Conformation of Polypeptides and Proteins
- I. Introduction
- II. Description of Polypeptide Conformation
- III. Analytical Calculation of Atomic Coordinates
- IV. Model Building of Polypeptide Structures
- V. Allowed Conformations of Polypeptide Chains
- VI. Calculation of Energies Associated with Conformations
- VII. Tests of the Different Potential Functions
- VIII. Conformations Observed for Amino Acids, Peptides, Polypeptides, and Proteins
- References
- Appendix: Revised Conventions for Describing Conformations of Polypeptides and Proteins
- Author Index
- Subject Index
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