Advances in Pharmacology
Academic Press
Published on 24. February 1992
344 pages
978-0-08-058114-9 (ISBN)
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Advances in Pharmacology
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M. W. Anders | Ferid Murad | J. Thomas August
Advances in Pharmacology: v. 23
Book
01/1992
Academic Press
€86.19
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Content
- Front Cover
- Advance in Pharmacology, Volume 23
- Copyright Page
- Contents
- Contributors
- Chapter 1. Advanced Glycosylation: Chemistry, Biology, and Implications for Diabetes and Aging
- I. Introduction
- II. Nonenzymatic Glycosylation
- III. Advanced Glycosylation
- IV. Biological Consequences of Advanced Glycosylation
- V. Pharmacological Inhibition
- VI. Conclusion
- References
- Chapter 2. Complex Carbohydrates in Drug Development
- I. Introduction
- II. Glycoconjugate Structure and Biosynthesis
- III. Bioactivity and Pharmaceutical Potential of Complex Carbohydrates
- IV. Conclusions and Perspectives
- References
- Chapter 3. New Developments in Enteric Bacterial Toxins
- I. Overview
- II. Cholera-like Enterotoxins (CT, LT-I, LT-II)
- III. Heat-Stable Enterotoxins (STa and STb)
- lV. Other Potential Escherichia coli and Vibrio cholerae Enterotoxins
- V. Clostridium difficile Toxins A and B
- VI. Shiga and Shiga-like Toxins
- VII. Staphylococcal Enterotoxins
- VIII. Clostridium Perfringens Enterotoxin A
- IX. Conclusion
- References
- Chapter 4. Superoxide Dismutase: Pharmacological Developments and Applications
- I. Introduction
- II. The Protein Chemistry and Enzymology of the Superoxide Dismutases
- III. The Superoxide Radical: Toxicity versus Reactivity
- IV. The Pathological Production of Superoxide Radical
- V. The Pharmacodynamics and Pharmacokinetics of the Superoxide Dismutases
- VI. Chemical Modification of Superoxide Dismutases
- VII. Genetic Modification of Superoxide Dismutases
- VIII. Down Syndrome and the Concept of "Oxidant-Antioxidant Balance"
- IX. Concluding Remarks
- References
- Chapter 5. Pharmacological Implications of Interleukin-5 in the Control of Eosinophilia
- I. Introduction
- II. Biochemistry of Interleukin-5
- III. Biological Properties of Interleukin-5
- IV. Control of Eosinophilia
- V. Eosinophils and Tumors
- VI. Eosinophils and Asthma
- VII. Summary and Overview
- References
- Chapter 6. Advances in Antiarrhythmic Drug Therapy
- I. Introduction
- II. Classification of Antiarrhythmic Drugs
- III. Applications of Classification Systems
- IV. Class I Antiarrhythmic Drugs
- V. Class II Antiarrhythmic Drugs
- VI. Class III Antiarrhythmic Drugs
- References
- Chapter 7. New Developments in Thrombolytic Therapy
- I. Introduction
- II. Currently Available Plasminogen Activators
- III. Antibody-Directed Thrombolysis
- lV. Plasminogen Plus Plasminogen Activator Combinations
- V. Thrombolysis and Anticoagulation
- VI. Thrombolysis and Platelets
- VII. Combinations of Plasminogen Activators
- VIII. Summary
- References
- Chapter 8. Therapy of Hematopoietic Disorders with Recombinant Colony-Stimulating Factors
- I. Overview of Normal Hematopoiesis
- II. Pharmacologic Principles of Colony-Stimulating Factor Therapy
- III. Clinical Uses of Colony-Stimulating Factors
- Refcrences
- Chapter 9. Mechanisms of Xenobiotic-Induced Renal Carcinogenicity
- I. Introduction
- II. Anatomy, Physiology, and Biochemistry of the Kidney
- III. Morphological and Biochemical Characteristics of Renal Tumors
- IV. Mechanistic Basis for the Nephrocarcinogenesis of Xenobiotics
- V. Conclusions
- References
- Index
- Contents of Previous Volumes
