
Advances in Pharmacology
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Content
- Front Cover
- Advances in Pharmacology, Volume 1
- Copyright Page
- Contributors to volume 1
- Preface
- Contents
- Chapter 1. A New Interpretation of the Adrenergic Nerve Fiber
- I. Introduction
- II. The Uptake of Noradrenaline from the Blood by Tissues with a Sympathetic Innervation
- III. The Action of the Sympathomimetic Amines
- IV. The Effect of Noradrenaline on Sympathetic Stimulation
- V. The Peripheral Actions of Acetylcholine and Nicotine
- VI. The Sympathetic Cholinergic Fibers
- VII. The Store of Noradrenaline
- VIII. Addendum on the Action of Cocaine
- IX. Summary
- References
- Chapter 2. Factors Influencing Drug Metabolism
- I. Introduction
- II. Stimulators of Drug Metabolism
- III. Inhibitors of Drug Metabolism
- IV. Physiological Factors Influencing Drug Metabolism
- V. Concluding Remarks
- References
- Chapter 3. Chemotherapeutic Approaches to the Problem of Hyperlipidemia
- I. Introduction
- II.The Relationship between Serum Lipid Levels and Atherosclerosis
- III. Therapeutic Approaches and Therapeutic Aims
- IV. Drug Screening and Clinical Evaluation
- V. Agents Inhibiting Cholesterol Biosynthesis
- VI. Agents Inhibiting Cholesterol Absorption
- VII. Agents Inhibiting Bile Acid Absorption
- VIII. Agents Accelerating Degradation and Excretion of Cholesterol
- IX. Conclusion
- References
- Chapter 4. Antihypertensive Drugs
- I. General Survey
- II. Ganglion Blockade
- III. Reserpine
- IV. Reserpine Analogs with Predominantly Peripheral Action
- V. Reserpine Derivatives with Predominantly Central Action
- VI. Xylocholine and Derivatives
- VII. Bretylium
- VIII. Guanethidine
- IX. Antagonists of Adrenaline and Noradrenaline
- X. Monoamine Oxidase Inhibitors
- XI. Decarboxylase Inhibitors
- XII. Serotonin Antimetabolites
- References
- Chapter 5. Pharmacological Aspects of Psychiatry
- I. Methods of Study
- II. Classification and Description of Psychotropic Drugs
- III. Chemical Aspects of Mental Disorder
- IV. Investigations Concerned with the Quantitative Effects of Psychotropic Drugs on Human Subjects
- V. Clinical Studies and Psychotropic Drugs
- VI. Conclusion
- References
- Chapter 6. Pharmacological Considerations of Antithrombotic Therapy
- I. Introduction
- II. Coumarins and Indanediones
- III. Heparin and Heparinoids
- IV. Fibrinolytic Agents
- V. Conclusion
- References
- Chapter 7. The Gastrointestinal Tract and Naturally Occurring Pharmacologically Active Amines
- I. Indolic Compounds and Related Substances on Gastrointestinal Motility and Gastric Secretion
- II. Histamine and the Gastrointestinal Tract
- III. Metabolism of Indolic Substances and Histamine in Gastrointestinal Diseases and in Germ Free Animals
- References
- Chapter 8. Binding of Some Biogenic Amines in Tissues
- I. Introduction
- II. Granular Bound Amines
- III. Release of Amines from Granules and Tissues
- IV. Binding of Exogenous Amines
- V. Substances That Have Been Implicated in the Binding of Amines
- VI. Types of Bonding
- VII. Summary
- References
- Author Index
- Subject Index
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