Advances in Immunology
Academic Press
Published on 13. June 1991
433 pages
978-0-08-057825-5 (ISBN)
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Advances in Immunology
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Advances in Immunology: v. 49
Book
04/1991
Academic Press
€84.95
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Content
- Front Cover
- Advances in Immunology, Volume 49
- Copyright Page
- Contents
- Chapter 1. Human Immunoglobulin Heavy-Chain Variable Region Genes: Organization, Polymorphism, and Expression
- I. Introduction
- II. Gross Organization of the Human Ig Complex
- III. VH Families
- IV. Polymorphism of VH Gene Segments
- V. D Segments
- VI. Human JH Segments
- VII. Expression of Human VH Gene Segments
- VIII. Regulation
- IX. Conclusions
- References
- Chapter 2. Surface Antigens of Human Leucocytes
- I. Introduction
- II. Antigen-Specific Receptors
- III. MHC Glycoproteins
- IV. Adhesion Molecules
- V. Receptors for Immunoglobulins (Fc-Receptors)
- VI. Receptors for Complement Components
- VII. Receptors for Lymphokines and Other Growth and Differentiation Factors
- VIII. Membrane Enzymes
- IX. Transport Proteins
- X. Other Interesting Molecules
- XI. Concluding Remarks
- References
- Note Added in Proof
- Chapter 3. Expression, Structure, and Function of the CD23 Antigen
- I. Introduction
- II. Cellular Expression
- III. Biochemical Structure
- IV. Regulation of CD23 Cleavage
- V. Regulation of CD23 Expression
- VI. Molecular Biology of FceRII
- VII. Biological Activity of CD23
- VIII. CD23 Expression in Various Clinical Conditions
- IX. Conclusions
- References
- Chapter 4. Immunology and Clinical Importance of Antiphospholipid Antibodies
- I. Introduction
- II. Phospholipid Biochemistry
- III. Historical Background
- IV. Clinical Aspects of Antiphospholipid Antibodies
- V. The Immunology of Antiphospholipid Antibodies
- VI. The Pathogenic Potential of aPL Antibodies
- VII. Summary and Conclusions
- References
- Chapter 5. Adoptive T Cell Therapy of Tumors: Mechanisms Operative in the Recognition and Elimination of Tumor Cells
- I. Introduction
- II. Principles of Adoptive Therapy with Specifically Immune T Cells
- III. Mechanisms by Which T Cells Mediate Tumor Rejection
- IV. Recognition of Distinct Tumor Antigens by CD4+ and CD8+ T Cells as a Potential Basis for Selective Efficacy of a T Cell Subset
- V. Accessory Cell, Antigen-Presenting Cell, and Cytokine Requirements for Effective Expression of Antitumor Responses by CD4+ and by CD8+ T Cell Subsets
- VI. Concluding Statements
- References
- Chapter 6. The Development of Rational Strategies for Selective Immunotherapy against Autoimmune Demyelinating Disease
- I. Introduction
- II. Multiple Epitopes of Myelin Basic Protein in Mice and Humans
- III. Human and Rodent TCR Usage Restriction in T Cells Responding to Specific Epitopes of Myelin Basic Protein
- IV. Possibilities for Future Immune Intervention in Multiple Sclerosis
- References
- Chapter 7. The Biology of Bone Marrow Transplantation for Severe Combined Immune Deficiency
- I. Introduction
- II. Severe Combined Immune Deficiency
- III. Characteristics of Stem Cell Engraftment for the Correction of SCID
- IV. Histocompatible Bone Marrow Transplantation
- V. Transplantation with Fetal Tissues
- VI. Bone Marrow Transplantation with T Cell-Depleted Haploidentical Bone Marrow
- VII. Lack of Stem Cell Engraftment
- VIII. Graft-versus-Host Disease
- IX. Tolerance
- X. Posttransplant Immunocompetence
- XI. Conclusions
- References
- Index
- Contents of Recent Volumes
