Advances in Immunology
Academic Press
Published on 10. November 1987
475 pages
978-0-08-057817-0 (ISBN)
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Advances in Immunology
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Frank J. Dixon
Advances in Immunology
Book
11/1987
Academic Press
€91.76
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Content
- Front Cover
- Advances in Immunology, Volume 41
- Copyright Page
- Content
- Chapter 1. Cell Surface Molecules and Early Events Involved in Human T Lymphocyte Activation
- I. Introduction
- II. Cell Surface Molecules Involved in T Cell Activation
- III. Synergy between Ca2+ Ionophores and Phorbol Esters in T Cell Activation
- IV. Receptor-Mediated Signal Transduction during T Cell Activation
- V. Role of Intracellular Signals Other Than Ca2+ and pkC
- VI. Effects of Early T Cell Activation Events upon Gene Regulation
- VII. Summary
- References
- Chapter 2. Function and Specificity of T Cell Subsets in the Mouse
- I. Introduction
- II. Cell Surface Molecules Controlling T Cell Specificity and Function
- III. H-2-Restricted Recognition of Antigen by Mature T Cells
- IV. Recognition of H-2 Alloantigens by Mature T Cells
- V. Consequences of T Cell Contact with H-2 Molecules in the Thymus
- VI. Summary
- References
- Chapter 3. Determinants on Major Histocompatibility Complex Class I Molecules Recognized by Cytotoxic T Lymphocytes
- I. Introduction
- II. Exon Shuffling to Produce Domaion Shuffled Milecules
- III. Recognition of HLA Class I Antigens on Transfected Cell
- IV. Role of Carbohydrate Moieties in Determining CTL Recognition of Class I Molecules
- V. Role of ß2-Microglobulin in T Cell Recognition of Class I Molecules
- VI. Use of Monoclonal Antibodies to Block CTL Recognition of Class I Molecules
- VII. Class I Heavy Chains Bearing Defined Amino Acid Changes: Effect on Polymorphic Determinants Recognized by CTL
- VIII. CTL Recognition of Monoclonal Antibody-Selected Somatic Cell Class I
- IX. Concluding Remarks
- References
- Chapter 4. Experimental Models for Understanding B Lymphocyte Formation
- I. An Introductory Overview
- II. Organization of Lymphohemopoietic Tissues
- III. Resolution of B Cell Precursors
- IV. Rearrangement and Utilization of Immunoglobullin Genes
- V. Population Dynamics
- VI. Long-Term Bone Marrow Cultures
- VII. An Inducible Cell Line
- VIII. Some Genetically Determited Defects
- IX. Soluble Mediators
- X. Synthesis and Conclusions
- References
- Chapter 5. Cellular and Humoral Mechanisms of Cytotoxicity: Structural and Functional Analogies
- I. Introduction
- II. Nature of Cytotoxicity Mediated by CTL and NK Cells
- III. Cytolytic Mechanisms Proposed in the Past and the Concept of Secretion and Colloid Osmotic Lysis
- IV. Granule Proteins in Cell-Mediated Killing
- V. Membrane Attack Complex of Complemen
- VI. Other Cytolytic Pore-Forming Proteins
- VII. Conclusion
- References
- Chapter 6. Biology and Genetics of Hybrid Resistance
- I. Introduction
- II. Hybrid Resistance to Normal Hemopoietic Cells
- III. Hybrid Resistance to Leukemia/Lymphoma Cells
- IV. Effector Mechanisms of Hybrid Resistance
- V. Genetics of Antigen Expression
- VI. Proposed Mechanisms of Antigens Expression and Machanism of Rejection
- References
- Index
- Content of Recent Volumes
