
Advances in Immunology
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Content
- Front Cover
- Advances in Immunology, Volume 39
- Copyright Page
- Contents
- Chapter 1. Immunological Regulation of Hematopoietic/Lymphoid Stem Cell Differentiation by Interleukin 3
- I. Introduction
- II. Biochemical Properties of T Cell-Derived Lymphokines
- III. Cellular Sources of Interleukin 3
- IV. Regulation of the Production of Interleukin 3
- V. Multiple Biological Activities Associated with Interleukin 3
- VI. Regulation of Hematopoietic/Lymphoid Stem Cell Differentiation
- VII. Potential Mechanisms for Interleukin 3 Regulation in Vivo
- VIII. Interleukin 3-Responsive Cell Lines: Origins and Properties
- IX. Mechanisms in Interleukin 3-Regulated Growth
- X. Summary and Conclusions
- References
- Chapter 2. Antigen Presentation by B Cells and Its Significance in T-B Interactions
- I. Introduction
- II. The Capacity of B Cells to Serve as Antigen-Presenting Cells
- III. The Fate of Antigen Taken up by B Cells
- IV. The Effect of B Cell Activation on APC Function
- V. The Capacity of B Cells to Function as Stimulator Cells in Mixed Lymphocyte Proliferative Responses
- VI. Differences in the Accessory Cell Function of B Cells Compared to Other Cell Types
- VII. Concluding Remarks
- References
- Chapter 3. Ligand-Receptor Dynamics and Signal Amplification in the Neutrophil
- I. Introduction
- II. Ligand-Receptor Dynamics
- III. Coupling Mechanisms
- IV. Signals
- V. Implications
- References
- Chapter 4. Arachidonic Acid Metabolism by the 5-Lipoxygenase Pathway, and the Effects of Alternative Dietary Fatty Acids
- I. Introduction
- II. Biosynthesis and Metabolic Inactivation of Arachidonic Acid-Derived Mediators
- III. Specific Enzymes in Leukotriene Biosynthesis and Processing
- IV. Cellular Specificity of Leukotriene Generation in Response to the Calcium Ionophore and Transmembrane Stimuli
- V. Biologic Effects of the Leukotrienes
- VI. Receptor-Dependent Mediation of Leukotriene Effects
- VII. Modulation of Arachidonic Acid Metabolism by the Introduction of Dietary Alternative Fatty Acids
- VIII. Biologic Properties of EPA and DCHA-Derived 5-Lipoxygenase Metabolites
- IX. Effects of EPA and DCHA in Animal Studies
- X. Effects of EPA and DCHA in Human Studies
- XI. Conclusions
- References
- Chapter 5. The Eosinophilic Leukocyte: Structure and Function
- I. Introduction
- II. Anatomical Characteristics
- III. Eosinophil-Associated Substances
- IV. Light Density Eosinophils
- V. Eosinophil Degranulation
- VI. Phagocytosis by Eosinophils
- VII. Eosinophils as an Effector Cell Damaging Parasites
- VIII. Eosinophils and Hypersensitivity Reactions
- IX. Eosinophils and Reproduction
- X. Summary and Conclusions
- References
- Chapter 6. ldiotypic Interactions in the Treatment of Human Diseases
- I. Introduction
- II. The Idiotype Network
- III. T Cells Involved in Idiotype-Determined Regulation
- IV. Regulation of the Normal Human Immune Response by Idiotypic Interactions
- V. Idiotypic Interactions and the Allergic Response
- VI. Idiotypic Interactions in Self-Tolerance and Autoimmunity
- VII. Idiotypic Network Regulations of Immune Responses to HLA Antigens
- VIII. Antiidiotypic Antibodies as Vaccines
- IX. Antiidiotypic Therapy in Human Tumors
- X. Conclusion
- References
- Chapter 7. Neuroimmunology
- I. Introduction
- II. Physiological and Pathophysiological Functions of Neuropeptides in Nonneural Tissues
- III. Mediation and Modulation of Immediate Hypersensitivity
- IV. Inflammation and Tissue Repair
- V. Lymphocyte Functions
- VI. Neuropeptide Receptors on Immune Cells
- VII. Thymic Factors
- VIII. Neuropeptides and Neuropeptide-Like Factors Endogenous to Cells of the Immune System
- IX. Possible Immunopathogenetic Roles of Neuropeptides
- X. Future Directions
- References
- Index
- Contents of Recent Volumes
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