
Advances in Genetics
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Content
- Front Cover
- Advances in Genetics
- Copyright page
- Contents
- Contributors
- Chapter 1: The Inspection Paradox and Whole-Genome Analysis
- I. Inspection Paradox
- II. Homozygosity Mapping
- III. X-Linked Mutations
- IV. Discussion
- References
- Chapter 2: Gene Expression Studies in Mosquitoes
- I. Introduction
- II. Study of Gene Expression in Mosquitoes
- III. Concluding Remarks
- References
- Chapter 3: Phylogeny of Tec Family Kinases: Identification of a Premetazoan Origin of Btk, Bmx, Itk, Tec, Txk, and the Btk Regulator SH3BP5
- I. Tyrosine kinases and the Tec family
- II. Aim of this Review
- III. The function of Individual Domains in TFKs
- IV. The Ancestry of TFKs
- V. SH3BP5-A Conserved Negative Regulator of TFKS
- VI. The Origin of Phosphotyrosine Signaling and the Role of Cytoplasmic Tyrosine Kinases
- References
- Chapter 4: Therapeutic Approaches to Ion Channel Diseases
- I. Introduction
- II. Pharmacotherapy of Ion Channelopathies
- III. Molecular Pharmacology of Ion Channels
- IV. Conclusions
- References
- Index
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