Advances in Genetics
Academic Press
Published on 6. September 2011
268 pages
978-0-08-092239-3 (ISBN)
Description
The field of genetics is rapidly evolving and new medical breakthroughs are occurring as a result of advances in knowledge gained from genetics research. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.
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Content
- Front Cover
- Advancesin Genetics
- Copyright Page
- Contents
- Contributors
- Chapter 1: Common Genetic Variation and Human Disease
- I. Introduction
- II. Variation in the Human Genome
- III. Utilization of Genetic Variation in Gene Mapping Studies
- IV. Mapping Complex Disease Genes Using Association
- V. Genome-Wide Association Studies
- VI. Study Design and Data Analysis
- VII. Significance for Public Health
- VIII. Concluding Remarks
- References
- Chapter 2: Genetics of the Framingham Heart Study Population
- I. Introduction
- II. The Study Population
- III. Phenotypic and Genetic Architecture of Complex Traits
- IV. Linkage and Association Studies
- V. Genotype-Environment Interactions
- VI. Ethical Issues
- VII. Prospects and Conclusions
- References
- Authors Note
- Chapter 3: Neurogenetics of Courtship and Mating in Drosophila
- I. Introduction
- II. Mutations and Genes Affecting Sensory Functions that Control Courtship
- III. Neurogenetics of the CNS's Control of Sex-Specific Behaviors
- IV. Genetic Manipulations of Experience-Dependent Reproductive Behavior
- V. Fruitless: A Crucial Single-Gene Regulator of Male-Specific Behavior and Sexual Differentiation of the Nervous Syst
- VI. Neurogenetic Relationships Between the Regulation of Reproduction and Rhythms
- VII. Conclusions and Prospects
- References
- Chapter 4: NMD: Multitasking Between mRNA Surveillance and Modulation of Gene Expression
- I. Introduction
- II. Mechanism and Actors
- III. Targets of NMD
- IV. Disobedient NMD Targets
- V. Good Cop, Bad Cop: Medical Importance of NMD
- VI. Moonlighting NMD Proteins: Moonlighting Pathway?
- VII. Conclusions
- References
- Index
- Color Plate Section
