Advances in Genetics
Academic Press
Published on 11. December 1987
528 pages
978-0-08-056811-9 (ISBN)
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Advances in Genetics
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12/1987
Academic Press
€115.95
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Content
- Front Cover
- Advances in Genetics: Molecular Genetics of Development
- Copyright Page
- Contents
- Preface
- Ernst W. Caspari: Geneticist, Teacher, and Mentor
- Chapter 1. Heat-Shock Proteins and Development
- I. Introduction and Overview
- II. Heat-Shock Proteins and Development in Animal Systems
- III. Heat-Shock Proteins and Development in Microorganisms
- IV. Tissue-Culture Systems
- V. Conclusion
- References
- Chapter 2. Mechanisms of Heat-Shock Gene Activation in Higher Eukaryotes
- I. Introduction
- II. The Heat-Shock Regulatory Element (HSE)
- III. The Heat-Shock Transcription Factor (HSTF)
- IV. Heat Induction of Heat-Shock Genes
- V. Developmental Activation of Heat-Shock Genes
- VI. Functions of Heat-Shock Proteins
- VII. The Connection between Gene Activation and Function: A Hypothesis
- Note Added in Proof
- References
- Chapter 3. Regulatory Gene Action during Eukaryotic Development
- I. Introduction
- II. Regulatory Genes of the Mouse
- III. Regulatory Genes of Drosophila
- IV. Regulatory Genes of Maize
- V. Regulatory Genes of Rainbow Trout
- VI. Discussion
- References
- Chapter 4. The Genetics of Biogenic Amine Metabolism, Sclerotization, and Melanization in Drosophila melanogaster
- I. Introduction
- II. General Comments on Biogenic Amine Metabolism
- III. Biogenic Amine Metabolism in Drosophila
- IV. Melanization, Quinone Sclerotization, and B-Sclerotization in Insects
- V. Developmental Profiles of Catecholamine Pools during Embryogenesis and after Adult Eclosion in Drosophila
- VI. The Genetics and Biology of Alkaline Phosphatase-1 and the Metabolism of Tyrosine-0-Phosphate
- VII. Dopa Decarboxylase in D. melanogaster
- VIII. Tyrosine and 5-Hydroxytryptophan Decarboxylase Activities
- IX. The Genetics of a-Methyldopa Sensitivity and Resistance
- X. The Ddc Cluster of Functionally Related Genes
- XI. The Genetics and Biology of Phenol Oxidase Activities
- XII. Dopamine Acetyltransferase
- XIII. The Genetics of ß-Alanine, Dopamine, and N-ß-Alanyldopamine Metabolism in Drosophila
- XIV. Two Additional Body Color Mutations
- XV. Concluding Remarks
- References
- Chapter 5. Developmental Control and Evolution in the Chorion Gene Families of Insects
- I. Introduction
- II. Sequences of Chorion Genes and Proteins
- III. Chromosomal Organization and Developmental Expression of Chorion Genes
- IV. The 5'-Flanking DNA Sequences of Chorion Genes
- V. Evolutionary Conservation of Regulatory Elements among Flies and Moths
- References
- Chapter 6. The Significance of Split Genes to Developmental Genetics
- I. Introduction
- II. The Concept of Maturase
- III. Ontogeny
- IV. Phylogeny
- V. General Conclusion
- References
- Chapter 7. Gene Transfer into Mice
- I. Preface
- II. Introduction
- III. Integration
- IV. Translocations
- V. Insertional Mutagenesis
- VI. Gene Expression
- VII. Developmental Stage-Specific Gene Expression
- VIII. Oncology
- IX. Immunology
- X. Correction of Genetic Deficiencies
- XI. Transgenic Mice as Models of Human Disease
- XII. Areas of Future Research
- References
- Chapter 8. The Molecular Basis of the Evolution of Sex
- I. The Benefit of Sex Is a Major Unsolved Problem
- II. Informational Noise: Damage, Mutation, and Recombination
- III. Overview of Repair Hypothesis
- IV. DNA Damage in Nature
- V. Recombinational Repair Is Efficient, Versatile, and Prevalent
- VI. Recombinational Repair: A Basic Feature of Sex
- VII. The Origin and Evolution of Sex Explained as a Continuum by the Repair Hypothesis
- VIII. Alternative Theories
- IX. Immortality of the Germ Line versus Mortality of the Somatic Line
- X. Summary and Conclusions
- References
- Chapter 9. Gene Dosage Compensation in Drosophila melanogaster
- I. Introduction
- II. Dosage Compensation Involves the Regulation of Transcription
- III. The X/A Ratio Is the Primary Determinant of Dosage Compensation
- IV. The Link between Dosage Compensation and Sex Determination
- V. Trans-Acting Regulators of Compensation
- VI. Evidence for Cis-Acting Regulatory Sequences Responsible for Dosage Compensation
- VII. Overview of the Regulation of Dosage Compensation
- VIII. Perspective
- References
- Chapter 10. Developmental Morphogenesis and Genetic Manipulation in Tissue and Cell Cultures of the Gramineae
- I. Introduction
- II. Developmental Morphogenesis
- III. Genetic Manipulation and Plant Improvement
- IV. General Conclusions
- References
- Index
- Curriculum Vitae: Ernst W. Caspari
- List of Publications: Ernst W. Caspari
