Advances in Cancer Research
Academic Press
Published on 12. July 1993
245 pages
978-0-08-056243-8 (ISBN)
Description
Advances in Cancer Research
More details
Other editions
Additional editions
Book
07/1993
Academic Press
€54.55
Article exhausted; check different version
Persons
Content
- Front Cover
- Advances in Cancer Research, Volume 61
- Copyright Page
- Contents
- Contributors to Volume 61
- Chapter 1. Cancer Prevention Research Trials
- I. Introduction
- II. Basic Research Studies: Surveying Basic Research
- III. The Research Strategy: From Basic Research to Human Applications
- IV. Progress in Clinical Trials
- V. Conclusions
- References
- Chapter 2. Molecular Genetic Changes in Human Breast Cancer
- I. Introduction
- II. Clinicopathological Aspects of Breast Cancer
- III. Genetic Changes in Human Breast Cancer
- IV. Genetic Predisposition to Breast Cancer
- V. Concluding Remarks
- References
- Chapter 3. Molecular Approaches to Cancer Therapy
- I. Introduction
- II. Cancer as a Molecular Disorder
- III. Molecular Diagnosis
- IV. Molecular Therapies
- References
- Chapter 4. Regulation and Mechanism of Mammalian Gene Amplification
- I. Introduction
- II. Regulation of Amplitication
- III. Primary Mechanisnis of Amplitication
- IV. Hypotheses Integrating Regulation of Amplifcation with the Chromatidic Telomere Fusion Model
- V. Evolution of Amplifecl DNA
- References
- Chapter 5. Unraveling the Function of the Retinoblastoma Gene
- I. Introduction
- II. Genetics of Retinoblastoma
- III. The RB1 Gene and Protein Product
- IV. Binding of Viral Oncoproteins to p110RB1
- V. Mechanisms of RBI Gene Regulation
- VI. Interaction of p110 RB1 with Cellular Proteins
- VII. Functions of p110 RB1
- VIII. Tissue Specific Susceptibility to RB1 Dysfunction
- IX. Addendum
- References
- Chapter 6. Tumor Promotion by Inhibitors of Protein Phosphatases 1 and 2A: The Okadaic Acid Class of Compounds
- I. Introduction
- II. Okadaic Acid Class Compounds
- III. Okadaic Acid and Its Derivatives
- IV. Calyculins
- V. Microcystins and Nodularin
- VI. Tautomycin
- VII. Hypotheses in Relation to Human Cancer
- VIII. Future Perspectives
- IX. Conclusion
- References
- Chapter 7. Oncogenic Basis of Radiation Resistance
- I. Introduction
- II. Radiation Response Phenotype
- III. Human and Rodent Cell Model Systems
- IV. Mitogenic Singles and Radiation Response
- V. Transformation and Radiation Resistance
- VI. Radiation-Resistant Phenotype: Cause or Effect
- VII. DNA Damage and Repair Cascede: Biochemical and Cellular Factor
- VIII. Modulation of Radtion Resistance rapeutic Iniplications of Oncogene Startagy
- IX. Conclusion
- References
- Indes
