Advances in Cancer Research
Academic Press
Published on 27. September 1983
331 pages
978-0-08-056221-6 (ISBN)
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Advances in Cancer Research
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George Klein | Sidney Weinhouse
Advances in Cancer Research: v. 39
Book
07/1983
Academic Press
€83.08
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Content
- Front Cover
- Advances in Cancer Research, Volume 39
- Copyright Page
- Contents
- Contributors to Volume 39
- Chapter 1. Neoplastic Development in Airway Epithelium
- I. Introduction
- II. Experimental Approaches and Methodologies
- III. Morphology of Acute Phase Responses-Early Induction Phase
- IV. Chronic Phase Responses
- V. Cell Population Studies during Neoplastic Development
- VI. Modifiers of Neoplastic Development in Airway Epithelium
- VII. Conclusions
- References
- Chapter 2. Concomitant Tumor Immunity and the Resistance to a Second Tumor Challenge
- I. Introduction
- II. Tumor Excision and Resistance to a Second Tumor Challenge: Sinecomitant Immunity
- III. Resistance of the Tumor-Bearing Host to a Second Tumor Challenge: Concomitant Tumor Immunity
- IV. Metastases as a Second Tumor Graft: Antimetastatic Concomitant Immunity
- V. Is the Status of Concomitant Immunity Unique for a Tumor-Host Relationship?
- VI. Mechanisms of Resistance of the Tumor-Rearing Host to a Second Tumor Graft
- VII. Mechanisms of the Inhibition of Metastases Development by the Primary Tumor
- VIII. Conclusion and Summary
- References
- Chapter 3. Antigenic Tumor Cell Variants Obtained with Mutagens
- I. Introduction
- II. Evidence for the Production of Tumor Cells with Increased Immunogenicity by Mutagen Treatment
- III. Immunogenic Variants Obtained in Vitro with Nitrosoguanidine Derivative MNNG
- IV. Immunogenic Tumor Cell Populations Obtained in Vivo with Triazenylimidazole Derivative DTIC
- V. Discussion
- References
- Chapter 4. Chromosomes and Cancer in the Mouse: Studies in Tumors Established Cell Lines, and Cell Hybrids
- I. Introduction
- II. T-Cell Leukemias
- III. B-Cell Leukemias
- IV. Plasmacytomas
- V. Evidence from Cell Lines for the Role of Chromosome 15
- VI. Viruses and Genes Related to Tumorigenesis
- VII. Do All Tumors Have Specific Chromosome Changes?
- VIII. Gene Amplification: Homogeneously Staining Regions and Double Minute Chromosomes
- IX. General Characteristics of Mouse Cell Lines
- X. Suppression of Tumorigenicity in Hybrid Cells
- XI. Chromosome Loss in Tumorigenic Hybrids
- XII. Chromosome 4, in Vitro Growth and Tumorigenicity
- XIII. Complementation Analysis and the Number of Genes Involved in Tumorigenicity
- XIV. Trisomy 15 in Tumorigenic Hybrids
- XV. Suppression of Tumorigenicity by DNA Fragments
- XVI. SV40-Induced Transformation and Tumorigenicity in Hybrid Cells
- XVII. Common Mechanisms of Tumor Suppression in Interspecific Hybrids
- XVIII. Genetic Basis of Transformation and Tumorigenicity
- XIX. Altered Hexose Transport in Malignant Cells
- XX. Host Cell Recruitment into Tumors via Cell Fusion
- XXI. Conclusions
- References
- Chapter 5. Polyomavirus: An Overview of Its Unique Properties
- I. Introduction
- II. Background
- III. Structural Organization of the Viral Genome
- IV. Comparison of the Polyomavirus and SV40 Genomes
- V. The Tumor Antigens
- VI. Mutants of Polyomavirus
- VII. Cellular Transformation
- VIII. The Lytic Cycle
- IX. Conclusions
- References
- Chapter 6. The Pathogenesis of Oncogenic Avian Retroviruses
- I. Introduction
- II. Possible Mechanisms of' Retrovirus Oncogenesis
- III. Diseases Caused by Avian Retroviruses
- IV. Pathogenesis of Transforming Retroviruses: The Role of v-onc Genes
- V. Pathogenesis of Nontransforming Retroviruses: The Possible Role of e-onc Genes
- VI. The Host Response
- VII. Conclusions and Prospects
- References
- Chapter 7. Adjuvant Chemotherapy for Common Solid Tumors
- I. Introduction
- II. Selection of Patients
- III. Selection of Drugs
- IV. Toxicity
- V. Breast Cancer
- VI. Malignant Melanoma
- VII. Lung Cancer
- VIII. Colorectal Cancer
- IX. Osteogenic Sarcoma
- X. Ovarian Carcinoma
- XI. Discussion
- References
- Index
- Contents of Previous Volumes
