Advances in Cancer Research
Academic Press
Published on 24. January 1975
377 pages
978-0-08-056202-5 (ISBN)
Description
Advances in Cancer Research
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George Klein | Sidney Weinhouse
Advances in Cancer Research: v. 20
Book
11/1974
Academic Press
€83.08
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Content
- Front Cover
- Advances in Cancer Research, Volume 20
- Copyright Page
- Contents
- Contributors to Volume 20
- Chapter 1. Tumor Cell Surfaces: General Alterations Detected by Agglutinins
- I. Introduction
- II. Correlation between Lectin Binding, Agglutinability, and the Transformed State
- III. Discussion on Possible Mechanisms of Agglutination
- IV. Relevance of Cell Surface Alterations in Growth Control
- V. Surface Changes in the Cell Cycle
- VI. Survey of Chemical Differences Found in the Surfaces of Transformed Cells
- VII. Conclusions
- References
- Chapter 2. Principles of Immunological Tolerance and Immunocyte Receptor Blockade
- I. Introduction
- II. Background Concepts about the Mechanism of Action of Antigens
- III. Possible Levels for Immunity-Tolerance Signal Discrimination
- IV. Tolerance Induced in T and B Lymphocytes by Soluble, Oligovalent Antigens
- V. Tolerance Induced in T and B Lymphocytes by Antigens Possessing Multiple Repeating Determinants
- VI. Tolerance in T and B Lymphocytes Produced by Antigen-Antibody Cornplexes
- VII. Effector Cell Blockade by Multivalent Antigens
- VIII. Suppressor T Cells
- IX. Relevance of Tolerance and Effector Cell Blockade to Cancer
- X. Summary
- References
- Chapter 3. The Role of Macrophages in Defense against Neoplastic Disease
- I. Introduction
- II. RES and Tumor Resistance
- III. Macrophages and Tumor Resistance
- IV. Conclusion
- References
- Chapter 4. Epoxides in Polycyclic Aromatic Hydrocarbon Metabolism and Carcinogenesis
- I. Introduction
- II. Metabolism of Polycyclic Aromatic Hydrocarbons
- III. Synthesis of Epoxy Derivatives of Polycyclic Aromatic Hydrocarbons
- IV. Metabolic Formation of Epoxides Derived from Polycyclic Aromatic Hydrocarbons
- V. Metabolic Reactions of Polycyclic Aromatic Hydrocarbon Epoxides
- VI. Chemical Reactions of Polycyclic Aromatic Hydrocarbon Epoxides
- VII. Reactions of Polycyclic Aromatic Hydrocarbon Epoxides with Constituents of Rodent Cells in Culture
- VIII. Biological Effects Produced by Polycyclic Aromatic Hydrocarbon Epoxides
- IX. Properties of Epoxides Formed on Olefinic Double Bonds Conjugated with Aromatic Ring Systems
- X. Discussion
- References
- Chapter 5. Virion and Tumor Cell Antigens of C-Type RNA Tumor Viruses
- I. Introduction
- II. Morphogenesis and Ultrastructure
- III. Physical Properties and Chemical Composition
- IV. Virus-Specific Structural Proteins
- V. Virus-Directed Intracellular Antigens
- VI. Virus-Induced Cell Surface Antigens
- VII. Concluding Remarks
- References
- Chapter 6. Addendum to "Molecular Repair, Wound Healing, and Carcinogenesis: Tumor Production a Possible OverheaIing?
- I. Introduction
- II. Repair Replication
- III. Wound Healing
- IV. Xeroderma Piginentosum
- V. The Implication of DNA, and the Bacterial Analogy
- VI. Repair and Carcinogenesis
- VII. Therapeutic Possibilities
- VIII. Conclusion
- References
- Subject Index
- Contents of Previous Volumes
