
Advances in Cancer Research
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Content
- Front Cover
- Advances in Cancer Research, Volume 19
- Copyright Page
- Contents
- Contributors to Volume 19
- Chapter 1. Comparative Aspects of Mammary Tumors
- I. Introduction
- II. Cattle and Horses
- III. Pigs, Sheep, and Goats
- IV. Mice, Rats, and Rabbits
- V. Zoo Animals and Subhuman Primates
- VI. Cats
- VII. Mammary Tumors in Dogs
- VIII. Mammary Tumors in Male Animals
- IX. Etiology of Mammary Tumors in Animals
- X. Treatment of Mammary Tumors in Animals
- XI. Miscellaneous Aspects of Animal Mammary Tumors
- XII. Conclusions
- References
- Chapter 2. The Cellular and Molecular Biology of RNA Tumor Viruses, Especially Avian Leukosis-Sarcoma Viruses, and Their Relatives
- I. Introduction
- II. Virions of Avian Leukosis-Sarcoma Viruses
- III. Classification of Rnadnaviruses and Comparison with Avian Leukosis- Sarcoma Viruses
- IV. Virus Replication
- V. Virus-Cell Interactions Which Do Not Yield Infectious Virus
- VI. Transformation
- VII. Genetic Variation
- VIII. Organization of Genome
- IX. Genes in Uninfected Cells Related to RNA Tumor Viruses
- X. Neoplastic Transformation in the Absence of Overt Infection with Transforming RNA Tumor Viriises
- References
- Chapter 3. Cancer, Differentiation and Embryonic Antigens: Some Central Problems
- I. Introduction
- II. Transformation-Associated Cellular Alterations
- III. The Organization of Differentiation
- IV. Differentiation and Cancer
- V. Biology of Maternal-Fetal Differences
- VI. Molecular Basis of Differentiation and Cancer
- VII. Conclusions
- References
- Chapter 4. Simian Herpesviruses and Neoplasia
- I. Introduction
- II. Oncogenic Herpesviruses of Squirrel and Spider Monkeys
- III. Discussion
- References
- Chapter 5. Cell-Mediated Immunity to Tumor Cells
- I. Introduction
- II. Immune Surveillance and the Role of Cell-Mediated Immunity
- III. In Vivo Studies of Cellular Immunity to Experimental Tumors
- IV. In Vitro Assays of Cell-Mediated Immunity to Experimental Tumors
- V. In Vivo Studies of Cellular Immunity to Human Tumors
- VI. In Vitro Assays of Cell-Mediated Immunity to Human Tumors
- VII. Mechanisms for Cellular Immune Reactions to Tumor Antigens
- VIII. Applications of the Assays of Cellular Immunity to Tumor Antigens
- References
- Chapter 6. Herpesviruses and Cancer
- I. Introduction
- II. The Prototype Cancer Virus
- III. Herpesvirus Etiology of Lymphoproliferative Disorders in Animals
- IV. Epstein-Barr Virus and Burkitt Lymphoma
- V. Lucké Herpesvirus of Frogs
- VI. Properties of Herpesviruses Associated with Human Neoplasia
- VII. Human Herpesviruses with Cell-Transforming Ability
- VIII. Herpesviruses Expression in Transformed Hamster Cells
- IX. Malignant Potential of Herpesvirus Transformants
- X. Summary and Conjecture
- References
- Chapter 7. Cyclic AMP and the Transformation of Fibroblasts
- I. Introduction
- II. Effects of Cyclic AMP on Cells
- III. Cyclic AMP Levels in Cells
- IV. Adenylate Cyclase
- V. Cyclic AMP Phosphodiesterases
- VI. What Is the Enzymatic Basis for the Rise in Cyclic AMP Levels in Contact-Inhibited Cells?
- VII. Cyclic AMP-Dependent Protein Kinase
- VIII. Host Mutants in Cyclic AMP Metabolism
- IX. Conclusion
- References
- Chapter 8. Tumor Angiogenesis
- I. Tumor Growth before and after Vascularization
- II. Experimental Prolongation of the Avascular State
- III. Comparison between Tumor Angiogenesis and Vascularization of Normal Tissues
- IV. Humoral Transmission of Tumor Angiogenesis
- V. Antiangiogenesis: A Possible Therapeutic Approach
- VI. Theoretical Considerations and Conclusion
- References
- Subject Index
- Contents of Previous Volumes
- Color Plate Section
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