Advances in Cancer Research
Academic Press
Published on 1. January 1967
386 pages
978-0-08-056193-6 (ISBN)
Description
Advances in Cancer Research
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A. Haddow | Sidney Weinhouse
Advances in Cancer Research: v. 10
Book
09/1967
Academic Press
€83.08
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Content
- Front Cover
- Advances in Cancer Research, Volume 10
- Copyright Page
- Contents
- Contributors to Volume 10
- Contents of Previous Volumes
- Chapter 1. Carcinogens. Enzyme Induction. and Gene Action
- I. Introduction
- II. Polycyclic Hydrocarbons and Enzyme Induction
- III. The Effect of Drugs and Insecticides on Liver Microsomal Enzymes
- IV. The Nature of the Microsomal Drug-Metabolizing Enzyme Systems
- V. Effect of Oncogenic Viruses on Enzyme Induction
- VI. Enzyme Induction in Rat Hepatoma
- VII. Pharmacological and Physiological Significance of Polycyclic Hydro- carbons and Drug-Induced Enzyme Activity
- VIII. The Mechanism of Polycyclic Hydrocarbon and Drug-Induced Increase in Enzyme Activity
- IX. Carcinogenesis and Gene Action
- References
- Chapter 2. In Vitro Studies on Protein Synthesis by Malignant Cells
- I. Introduction
- II. Current Concepts of Protein Biosynthesis
- III. Protein Synthesis by in Vitro Systems Derived from Tumor Cells
- IV. Comparison of Protein Synthesis in Tumor with Microbial and Normal Mammalian Systems
- V. Summary and Conclusions
- References
- Chapter 3. The Enzymic Pattern of Neoplastic Tissue
- I. General Ideas about Ncoplasia
- II. The Measurement of Enzymes in Tissues and the Prediction of Metabolic Behavior
- III. Glycolysis and the Enzymes of Glycolysis
- IV. Glycerolphosphate Dehydrogenase levels and Glycolysis
- V. The Enzymes of the Pentose Pathway
- VI. Enzymes of Gluconeogenesis and Glycogen Formation
- VII. Tentative Formulation of the Pattern of Enzymes in Neoplastic Tissues
- VIII. Discussion
- References
- Chapter 4. Carcinogenic Nitroso Compounds
- I. Introduction
- II. Chemistry
- Ill. Acute Toxic Effects
- IV. Neoplastic Changes
- V. Some Special Features of Nitroso Compounds as Carcinogens
- VI. Mutagenic Action
- VII. Metabolism of Nitroso Carcinogens
- VIII. Biochemical Effects
- IX. Reactions with Cell Constituents
- X. Possible Mechanisms of Action
- XI. Public Health Aspects
- References
- Chapter 5. The Sulfhydryl Group and Carcinogenesis
- I. Introduction
- II. The SH Group and Normal Cell Division and Growth
- III. The Stimulation of Cell Division by SH Groups
- IV. SH-SS Cycles in Cell Division
- V. Growth Inhibition and Stimulation by Carcinogenic Substances
- VI. The Interaction of Carcinogens with SH Groups
- VII. The Interaction of SH-Reactive Substances of Unknown Carcinogenic Activity or without Carcinogenic Activity
- VIII. The SH Group in Carcinogenesis
- IX. SH Metabolic Systems Possibly Involved in Carcinogenesis
- X. Other SH Systems and Carcinogens
- XI. Discussion
- References
- Chapter 6. The Treatment of Plasma Cell Myeloma
- I. Introduction
- II. Plasma Cell Neoplasms
- III. Antineoplastic Treatment of Plasma Cell Myeloma
- IV. Summary
- References
- Author Index
- Subject Index
