
Advances in Cancer Research
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Content
- Front Cover
- Advances in Cancer Research
- Copyright Page
- Contents
- Contributors to Volume 6
- Chapter 1. Blood Enzymes in Cancer and Other Diseases
- I. Introduction
- II. Enzymes in the Erythrocyte
- III. The Reticulocyte
- IV. Platelets and the Clotting Enzymes
- V. Leucocytes
- VI. Enzymes in Serum
- VII. Concluding Remarks
- References
- Chapter 2. The Plant Tumor Problem
- I. Introduction
- II. Experimental Studies
- References
- Chapter 3. Cancer Chemotherapy by Perfusion
- I. Introduction
- II. Techniques
- III. Escape of Agent from the Perfusion Circuit
- IV. Dosage
- V. Pathologic Changes Resulting from Perfusion
- VI. Clinical Experience
- References
- Chapter 4. Viral Etiology of Mouse Leukemia
- I. Incidence and Induction of Mouse Leukemia
- II. The Search for a Leukemic Agent
- III. The Mouse Leukemia Virus
- IV. Radiation-Induced Leukemia in Mice
- V. Development of Leukemia Following Inoculation of Newborn Mice with Cell-Free Extracts Prepared from Mouse Tumors
- VI. The Search for a Leukemogenic Agent in Brains of Leukemic Donors
- VII. Summary and Conclusions
- References
- Chapter 5. Radiation Chimeras
- I. General Introduction
- II. History
- III. Method
- IV. Effects of Irradiation Not Altered by Hematopoietic Tissue Therapy
- V. Methods of Identification of the Chimeric State
- VI. Repopulation by Donor Cells and Stability of the Chimeric State
- VII. Patterns of Survival
- VIII. Immunology
- IX. General Discussion on Radiation Chimerism
- X. The Applications of Bone Marrow Therapy
- Appendix
- References
- Chapter 6. Etiology and Pathogenesis of Mouse leukemia
- I. Introduction
- II. Leukemogenic Agents
- III. Genetic Factors Influencing Susceptibility to Leukemia
- IV. Maternal Influence
- V. Influence of Age
- VI. Nutritional Factors
- VII. Endocrine Factors
- VIII. Thymic Factors
- IX. Hematopoietic Factors
- X. Immunogenetic Factors
- XI. Chromosomes of Mouse Leukemia
- XII. Leukemogenesis by Carcinogenic Hydrocarbons
- XIII. Leukemogenesis by Ionizing Radiations
- XIV. Leukemogenesis by Viruses
- XV. General Discussion
- References
- Chapter 7. Antagonists of Purine and Pyrimidine Metabolites and of Folk Acid
- I. Introduction
- II. Antipyrimidines
- III. Antipurines
- IV. Antagonista of Folic Acid
- V. A Relationship between Antipurines and Antifolic Acids and the Action of Hormones
- VI. A Conceivable Relation between the Mechanisms of Action of the Biological Alkylating Agents and Purine Antimetabolites
- References
- Chapter 8. Behavior of Liver Enzymes in Hepatocarcinogenesis
- I. Introduction
- II. Biological Aspects of Liver Carcinogenesis
- III. Basic Considerations in the Evaluation of Enzymatic Results in Neoplastic Studies
- IV. The Novikoff Hepatoma
- V. The Morris Hepatoma #5123
- VI. Biochemical Parameters and Enzyme Behavior during Hepatocarcinogenesis and in Primary Tumors
- VII. Behavior of Enzyme Forming Systems in Liver Neoplaaia
- VIII. Concluding Remarks
- References
- Author Index
- Subject Index
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