Controversies in the Management of Liver Metastases
Special Topic Issue: Digestive Surgery 2008, Vol. 25, No. 6
1st Edition
Published on 17. February 2009
Book
Paperback/Softback
90 pages
978-3-8055-9047-1 (ISBN)
Description
While considerable progress has been made in both surgical treatment of liver metastases and neoadjuvant or postoperative chemotherapy, decision making has become more complex. The definition of accurate measures is very difficult because there exists no consensus regarding pre- or postoperative predictors of survival in patients undergoing liver resection: Even though PET is well established in the diagnosis of colorectal cancer and its metastases, it is unclear whether a combination of imaging modalities will be of additional value. Neoadjuvant strategies are very efficient in downsizing metastasis, but they at the same time reduce functional liver reserve due to chemotherapy-induced liver injury. The advantages and disadvantages of the 'liver first' approach are likewise discussed, as are controversial issues in the use of portal vein embolization and radiofrequency ablation versus resection. Even though the main focus of this publication is on colorectal liver metastases, other primary cancers also receive some attention: Papers on resection of liver metastases combined with primary cancers conclude the discussions. This collection of papers provides valuable information on the many issues connected with the management of liver metastases, both colorectal and non-colorectal. Surgeons confronted with the question as to the best treatment strategy will find it a very helpful aid in their decision process.
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T.M. van Gulik | R. Adam
Controversies in the Management of Liver Metastases
Special Topic Issue: Digestive Surgery 2008, Vol. 25, No. 6
Online / Databases
02/2009
1st Edition
S. Karger
€51.15
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Content
Editorial: Controversies in the Management of Liver Metastases: van Gulik, T.M.; Adam, R.; Predictive Models in Colorectal Liver Metastases - Can We Personalize Treatment and Outcome?: Welsh, F.K.S.; Tekkis, P.P.; John, T.G.; Rees, M.; Controversies in the Management of Colorectal Liver Metastases: Role of PET and PET/CT: Wiering, B.; Vogel, W.V.; Ruers, T.J.M.; Oyen, W.J.G.; Chemotherapy prior to Hepatic Resection for Colorectal Liver Metastases: Helpful until Harmful?: Abdalla, E.K.; Vauthey, J.-N.; 'Liver First' Approach in the Treatment of Colorectal Cancer with Synchronous Liver Metastases: Mentha, G.; Roth, A.D.; Terraz, S.; Giostra, E.; Gervaz, P.; Andres, A.; Morel, P.; Rubbia-Brandt, L.; Majno, P.E.; Controversies in the Use of Portal Vein Embolization: van Gulik, T.M.; van den Esschert, J.W.; de Graaf, W.; van Lienden, K.P.; Busch, O.R.C.; Heger, M.; van Delden, O.M.; Lameris, J.S.; Gouma, D.J.; Radiofrequency Ablation versus Resection for Resectable Colorectal Liver Metastases: Time for a Randomized Trial? An Update: Mulier, S.; Ruers, T.; Jamart, J.; Michel, L.; Marchal, G.; Ni, Y.; Resection of Colorectal Liver Metastases with Extrahepatic Disease: de Haas, R.J.; Wicherts, D.A.; Adam, R.; Treatment of Melanoma Metastases Confined to the Liver and Future Perspectives: Vahrmeijer, A.L.; van de Velde, C.J.H.; Hartgrink, H.H.; Tollenaar, R.A.E.M.; Resection of Primary Pancreatic Cancer and Liver Metastasis: A Systematic Review: Michalski, C.W.; Erkan, M.; Huser, N.; Muller, M.W.; Hartel, M.; Friess, H.; Kleeff, J.