Epigenetic Technological Applications
Published on 28. July 2015
Book
Hardback
516 pages
978-0-12-801080-8 (ISBN)
Description
Epigenetic Technological Applications is a compilation of state-of-the-art technologies involved in epigenetic research. Epigenetics is an exciting new field of biology research, and many technologies are invented and developed specifically for epigenetics study. With chapters covering the latest developments in crystallography, computational modeling, the uses of histones, and more, Epigenetic Technological Applications addresses the question of how these new ideas, procedures, and innovations can be applied to current epigenetics research, and how they can keep pushing discovery forward and beyond the epigenetic realm.
More details
Language
English
Place of publication
San Diego
United States
Publishing group
Elsevier Science Publishing Co Inc
Target group
Professional and scholarly
Researchers in genetics, biology, biochemistry, and biophysics, and pharmaceutical and biotechnological industry scientists
Product notice
sewn/stitched
Cloth over boards
Illustrations
50
Dimensions
Height: 236 mm
Width: 191 mm
Thickness: 30 mm
Weight
1338 gr
ISBN-13
978-0-12-801080-8 (9780128010808)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Ya-Ping George Zheng
Epigenetic Technological Applications
E-Book
01/2015
Elsevier
€92.95
Available for download
Person
Content
Preface1. Introduction of the Epigenetic Technologies2. Technologies for the Measurement and Mapping of Genomic 5-methylcytosine and 5-hydroxymethylcytosine3. Technologies to Map DNA 5hC and 5fC and 5caC4. Application of Mass Spectrometry in Translational Epigenetics5. Techniques Analyzing Chromatin Modifications at Specific Single Loci6. Comprehensive Analysis of Mammalian Linker-histone Variants and Their Mutants7. Crystallography-based Mechanistic Insights into Epigenetic Regulation8. Chemical and Genetic Approaches to Study Histone Modifications9. Peptide Microarrays for Profiling of Epigenetic Targets10. Current Methods for Methylome Profiling11. Bioinformatics and Biostatistics for Mining Epigenetic Disease Markers and Targets12. Computational Modeling to Elucidate Molecular Mechanisms of Epigenetic Memory13. DNA Methyltransferase Inhibitors for Cancer Therapy14. Histone Acetyltransferases: Enzymes, Assays, and Inhibitors15. In Vitro Histone Deacetylase Activity Screening: Making a Case for Better Assays 16. Enzymatic Assays of Histone Methyltransferase Enzymes17. Histone Methyltransferase Inhibitors for Cancer Therapy18. Discovery of Histone Demethylase Inhibitors19. Fluorescent Technologies in Studying Dynamics of Histone Modification20. Animal Model Study of Epigenetic Inhibitors