Gene Technology

1 Stem Cells.- Hematopoietic Differentiation of Embryonal Stem Cells in Vitro.- Post-irradiated Canine Serum (PICS-J) Stimulates Megakaryocyte (MK) Progenitors and Thrombopoiesis in Vitro.- The Adhesion Molecules, PECAM-1, ICAM-3 and CD33, on CD34+ Hematopoietic Progenitor Cells.- Hematopoietic Stem Cell: Developmental Potential and Proliferative Activity.- The Effect of Methylprednisolone on Bone Marrow and Spleen Clonogenic Fibroblasts in Humans.- Umbilical Cord Blood: Morphological Composition and Functional Characteristics.- Stroma Cell Dependent Leukemias Growth of PGM-1 Leukemia cells on Stromal Layers.- 2 Genes Crucial for Development and Disease.- The Role of Non-Receptor Protein Tyrosine Kinases in Receptor Mediated Cellular Activition and Immunodeficiency Disease.- Directed Gene Trapping in Embryonic Stem Cells.- Molecular Basis of Genetic Disorders of Pigmentation in Humans and Mice.- MDR-1 Gene Expression in Chronic Myelogeneous Leukemia : Prognostic Marker of the Disease.- 3 Methods of Gene Transfer, Applications for Gene Therapy.- Towards Gene Therapy for Haemophilia B.- Inhibition of Autocrine TGF-f3 in CD34+ Human Progenitor Cells Reveals Their Potentiality to Engraft Adults and Improves Gene Transfer Efficiency.- Gene Transfer into Hematopoietic Progenitors: Implications for Bone Marrow Transplantation.- Erythropoietin and the ENV gp55 of the Spleen Focus Forming Virus (SFFV) Interact Differently with Erythroid Cells in the Mouse and in Tissue Culture.- Contribution of the Retroviral Leader to Gene Transfer and Expression in Packaging Cells and Myeloid Stem and Progenitor Cells.- Site-directed Mutagenesis of the cGMP Phosphodiesterase InhibitoryTSubunit from Bovine Rods: New Mechanisms of Catalytic Subunits Inhibition and Activation.- 4 Oncogenes and Antioncogenes as Targets for Gene Therapy.- Genetic Approaches to Defining Signaling by the CMLAssociated Tyrosine Kinase BCR-ABL.- Analysis of Oncosuppressor Gene Function in the Mouse by Gene Targeting.- 5 Receptors and Their Ligands in Normal Development and Disease.- Cloning of Retroviral Insertion Sites Possibly Involved in Growth-Factor Autonomy.- Function of the IL-3 Receptor System in Human Hematopoiesis.- Altered Growth Factor Response in Myeloid Progenitor Cell Mutants Derived After Retroviral Insertional Mutagenesis.- Signaling by the Erythropoietin Receptor in Retrovirally Transduced Normal Hematopoietic Progenitors: A Conserved Proline-Rich Motif Is Required for Association with JAK2.- Spontaneous Knockout of CSF-1 Gene in the Mouse as a Model to Study the Organization of the Macrophage System.- 6 Immunology and Immunotherapy.- Lifting a Tip of the Veil of Human Minor Histocompatibility Antigens.- Immune Escape Through T-cell Antagonism?.- The Privilege of Expressing CD44v - Used by Immune Cells, Misused by Tumor Cells.- Transplantation Immunology: Peptides in the Groove Cause Histoincompatibility.- 7 Radiation Biology.- Coupling of Membrane Pathology and DNA Damage in Irradiated Lymphoid Cell Populations.- Effects of Radiation on the Plasma Membrane and Expression of Membrane Bound Hematopoietic Cytokines.- 8 Clinical Leukemias.- Prognostic Value of Day 8 Peripheral Blood Response for Children with Acute Lymphocytic Leukemia.- GM-CSF in Addition to Chemotherapy of ALL for Kinetics Based Protection of Stem Cells and Stimulation of Haemopoiesis. A Randomized Study.- Cytogenetic Abnormalities and Their Clinical and Prognostic Value in Acute Leukemia.- Production of lnterleukin-2 and Natural Killer (NK) Activity in Patients with Multiple Myeloma.- Multiple Myeloma Associated with Amyloidosis.- Distribution of HLA-DRB1 Alleles in Patients with Chronic Myelogenous Leukemia Differs from That in Healthy Donors.- The Relationship of MDR-1 Gene Expression and Chemotherapy Regimens in Acute Leukemia.- Immunophenotyping of Blast Crisis During the Chronic Myelogenous Leukemia.- The Treatment of Acute Lymphoblastic Leukemia in Children According to BFM Protocols.- 9 Bone Marrow Transplantation.- Carcinoembryonic Antigen (CEA) in Blood Serum of Patients with Bone Marrow Transplantation.- Cytogenetic Monitoring in the Post BMT Period.- First Experience in the Field of Bone Marrow Transplantation at the St. Petersburg BMT Center.- Immunoglobulin E Levels in Allogenic BMT.- Prognostic Factors and Indications for Haemopoietic Stem Cells Transplantation in Patients with Multiple Myeloma.- Mobilization of Progenitor Cells for Autologous and Allogeneic Transplantation.- Transfusion Problems of Allogenic Bone Marrow Transplantation (BMT).