Myocardial Protection
The Pathophysiology of Reperfusion and Reperfusion Injury
Published on 1. January 1992
Book
Hardback
240 pages
978-0-88167-865-9 (ISBN)
Description
This volume provides insight into current theories and controversies regarding myocardial reperfusion and reperfusion-induced injury. The concepts presented aim to advance the understanding of the direct relationship of reperfusion injury to the beneficial effects of restoring coronary flow to the myocardium after an ischemic insult. Additional chapters examine myocardial adaptive responses to ischemia, particularly the myocardial protective effects of ischemic preconditioning and stress protein synthesis. The book concludes with a discussion of current and future approaches to the problems associated with reperfusion injury.
This volume provides insight into current theories and controversies regarding myocardial reperfusion and reperfusion-induced injury. The concepts presented aim to advance the understanding of the direct relationship of reperfusion injury to the beneficial effects of restoring coronary flow to the myocardium after an ischemic insult. Additional chapters examine myocardial adaptive responses to ischemia, particularly the myocardial protective effects of ischemic preconditioning and stress protein synthesis. The book concludes with a discussion of current and future approaches to the problems associated with reperfusion injury.
This volume provides insight into current theories and controversies regarding myocardial reperfusion and reperfusion-induced injury. The concepts presented aim to advance the understanding of the direct relationship of reperfusion injury to the beneficial effects of restoring coronary flow to the myocardium after an ischemic insult. Additional chapters examine myocardial adaptive responses to ischemia, particularly the myocardial protective effects of ischemic preconditioning and stress protein synthesis. The book concludes with a discussion of current and future approaches to the problems associated with reperfusion injury.
More details
Language
English
Place of publication
Philadelphia
United States
Target group
College/higher education
Professional and scholarly
Dimensions
Height: 279 mm
Width: 216 mm
Weight
570 gr
ISBN-13
978-0-88167-865-9 (9780881678659)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Content
Reperfusion injury - definitions and historical background, Robert B. Jennings and Derek M. Yellon; myocardial injury during ischemia and reperfusion - concepts and controversies, David J. Hearse; do free radicals contribute to myocardial cell death during ischemia-reperfusion?, James M. Downey and Derek M. Yellon; the contribution of neutrophil activation and changes in endothelial function to myocardial ischemia-reperfusion injury, Kevin M. Mullane and Mark Young; consequences of ischemia-reperfusion on the coronary microvasculature, Robert A. Kloner and Karin Przykenk; postischemic myocardial "Stunning" - pathogenesis, pathophysiology and clinical relevance, Roberto Bolli; reperfusion injury - a clinical perspective, Keigh A.A. Fox; preconditioning - definitions, proposed mechanisms, and implications for myocardial protection in ischemia and reperfusion, Keith A. Reimer and Robert B. Jennings; stress proteins and myocardial protection during ischemia and reperfusion, Derek M. Yellon and David S. Latchman; where do we stand with respect to reperfusion in the 1990s? Clinical and experimental perspective, Lionel H. Opie.