Organic Syntheses

Discussion Addendum for: 4-Nonylbenzoic Acid 1 Alois Fürstner Late-Stage Deoxyfluorination of Phenols with PhenoFluorMix 16 Junting Chen and Tobias Ritter Nickel-Catalyzed Cross-Coupling of 2-Methoxynaphthalene with Methyl 4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate 36 Yuki Kawashima, Takayuki Furukawa, Naoto Chatani and Mamoru Tobisu Discussion Addendum for: Lithium Amides as Homochiral Ammonia Equivalents for Conjugate Additions to alpha,ß-Unsaturated Esters: Asymmetric Synthesis of (S)-ß-Leucine 53 Stephen G. Davies, Ai M. Fletcher, Paul M. Roberts, and James E. Thomson Synthesis of 2,3-Diaryl-2H-azirines via Cs2CO3-Mediated Cyclization of Ketoxime Acetates 66 Mi-Na Zhao and Zheng-Hui Guan Discussion Addendum for: The Direct Acyl-Alkylation of Arynes. Preparation of Methyl 2- (2-acetylphenyl)acetate 80 Austin C. Wright and Brian M. Stoltz Discussion Addendum for: Convenient Preparation of 3-Ethoxycarbonyl Benzofurans from Salicylaldehydes and Ethyl Diazoacetate 98 Mizzanoor Rahaman and M. Mahmun Hossain Discussion Addendum for: Phosphine-Catalyzed [4 + 2] Annulation: Synthesis of Ethyl 6-Phenyl-1-tosyl-1,2,5,6-tetrahydropyridine-3-carboxylate 110 Aslam C. Shaikh and Ohyun Kwon Discussion Addendum for: Protection of Alcohols using 2-Benzyloxy-1-methylpyridinium Trifluoromethanesulfonate: Methyl (R)-(-)-3-Benzyloxy-2-methyl Propanoate 124 Harvey F. Fulo, Philip A. Albiniak, and Gregory B. Dudley Synthesis of 4-Methylbenzoate(2',4',6'-trimethoxy-phenyl)iodonium Tosylate 137 Thomas L. Seidl, Aaron Moment, Charles Orella, Thomas Vickery, and David R. Stuart Gold-Catalyzed Oxidative Coupling of Arenes and Arylsilanes 150 Chris Nottingham, Verity Barber, and Guy C. Lloyd-Jones Discussion Addendum for: Preparation of Enantioenriched Homoallylic Primary Amines 179 Miguel Yus Discussion Addendum for: Synthesis of Ynamides by Copper-Mediated Coupling of 1,1-Dibromo-1-alkenes with Nitrogen Nucleophiles. Preparation of 4-Methyl-N-(2-phenylethynyl)-N-(phenylmethyl)benzenesulfonamide 195 Cédric Theunissen, Pierre Thilmany, Mounsef Lahboubi, Nicolas Blanchard, and Gwilherm Evano Discussion Addendum for: Phosphine-Catalyzed [3 + 2] Annulation: Synthesis of Ethyl 5-(tert-Butyl)-2-phenyl-1-tosyl-3-pyrroline-3-carboxylate 214 Aslam C. Shaikh and Ohuyn Kwon Discussion Addendum for: Synthesis of Highly Enantiomerically Enriched Amines by Asymmetric Transfer Hydrogenation of N-(tert-Butylsulfinyl) Imines 232 Miguel Yus Synthesis of Chiral Diamine Ligands for Nickel-catalyzed Asymmetric Cross-couplings of Alkylchloroboronate Esters with Alkylzincs: 1R,2R)-N,N'-Dimethyl-1,2-bis(2-methylphenyl)-1,2-diaminoethane 245 Yusuke Masuda and Gregory C. Fu Preparation of 5-(Triisopropylalkynyl) dibenzo[b,d] thiophenium triflate 258 Bernd Waldecker, Kevin Kafuta, and Manuel Alcarazo Three-Step Synthesis of 2-(Diiodomethyl)-4,4,5,5-tetramethyl- 1,3,2-dioxaborolane from Dichloromethane 277 Morgane Sayes, Guillaume Benoit, and André B. Charette Discussion Addendum for: Allylic Oxidation Catalyzed by Dirhodium(II) Tetrakis[epsilon-caprolactamate] of tert-Butyldimethylsilylprotected trans-Dehydroandrosterone 300 Yong-Liang Su, Luca De Angelis and Michael P. Doyle Preparation of (R)-3-(3,5-Bistrifluoromethylphenyl)-1,1'-bi-2-naphthol 312 Yusuke Kobayashi, Atsushi Matsuda, Tomoya Ushimaru, and Toshiro Harada Catalytic Enantioselective Addition of an In-Situ Prepared Aryltitanium Reagent to p-Chloroacetophenone: (R)-(+)-1-(4-Chlorophenyl)-1-m-tolylethanol 333 Yusuke Kobayashi, Atsushi Matsuda, Tomoya Ushimaru, and Toshiro Harada Stereoselective Synthesis of (R)-((R)-1-Phenyl-2,2,2-trichloroethyl)-2-(2-bromophenyl)aziridine-1-carboxylate 351 Hélène Lebel and Henri Piras Discussion Addendum for: Preparation of (R,R)-1,2:4,5-Diepoxypentane 361 Nicholas Sizemore and Scott D. Rychnovsky (R)-N,N'-Dimethyl-1,1'-binaphthyldiamine 382 Scott E. Denmark and Pavel Ryabchuk Preparation of a Diisopropylselenophosphoramide Catalyst and its Use in Enantioselective Sulfenoetherification 400 Scott E. Denmark, Pavel Ryabchuk, Hyung Min Chi, and Anastassia Matviitsuk anti-1,2,2,3,4,4-Hexamethylphosphetane 1-Oxide 418 Trevor V. Nykaza, Julian C. Cooper, and Alexander T. Radosevich Facile Reduction of Amides Using Nickel Catalysis: Reduction of 12-Aminododecanolactam 436 Bryan J. Simmons, Melissa Ramirez, and Neil K. Garg Preparation of 2,4,5,6-Tetra(9H-carbazol-9-yl)isophthalonitrile 455 Saskia M. Engle, Takisha R. Kirkner, and Christopher B. Kelly Discussion Addendum for: Fluorobis(phenylsulfonyl)methane (FBSM) 474 Xanath Ispizua-Rodriguez, Vinayak Krishnamurti, Mathew Coe, and G. K. Surya Prakash Synthesis of 5-Hydroxy-4-methoxy-2-methylpyrylium Trifluoromethanesulfonate from Kojic Acid 494 Nana B. Agyemang and Ryan P. Murelli Iridium-Catalyzed Reductive Coupling of Grignard Reagents and Tertiary Amides 511 Pablo Gabriel, Lan-Gui Xie, and Darren J. Dixon Synthesis of Chiral Tetramic Acids: Preparation of (S)-5-Benzylpyrrolidine-2,4-dione from L-Phenylalanine Methyl Ester Hydrochloride 528 Kyle M. Lambert, Austin W. Medley, Amy C. Jackson, Lauren E. Markham, and John L. Wood Synthesis of 8-Hydroxygeraniol 586 Francesca M. Ippoliti, Joyann S. Barber, and Neil K. Garg