Epigenetics
Published on 26. February 1998
Book
Hardback
300 pages
978-0-471-97771-1 (ISBN)
Description
This volume uses the knowledge of basic transcriptional control as a foundation to explore the more complex levels at which genes can be regulated. Areas discussed in detail include the role of chromosomal domains in gene silencing, the parameters that determine the activity of transgenes in plants and animals, the host defence mechanisms that protect organisms from the danger of integrating foreign DNA into their chromosome, and the importance of genomic imprinting in development and human disease.
More details
Series
Language
English
Place of publication
Chichester
United Kingdom
Publishing group
John Wiley and Sons Ltd
Target group
College/higher education
Professional and scholarly
Illustrations
references
Dimensions
Height: 235 mm
Width: 155 mm
Weight
640 gr
ISBN-13
978-0-471-97771-1 (9780471977711)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Derek J. Chadwick | Gail Cardew
Epigenetics
E-Book
04/2008
1st Edition
Wiley
€108.99
Available for download
Content
Gene silencing by methyl-Cpg-binding proteins; DNA methylation, the nucleosome and the inheritance of chromatin structure; Pcg/Trx-induced heritable chromatin states; variegation of position; an epigenetic mechanism regulates silencing, directionality and recombination suppression in fission yeast; nuclear organization and silencing - the comings and goings of sirs; regulation of the maize suppressor (mutator transposon; co-suppression of homologous genes in plants and epigenetic switches in gene expression; homology-dependent gene silencing in transgenic plants; cytosine methylation and the control of intragenomic parasites; structure and function of the mammalian X chromosome inactivation centre; methylation dynamics, epigenetic fidelity and X chromosome structure; gene imprinting in the mouse; making sense of imprinting the mouse and human IGF2R locus; imprinted genes in the Prader-Willi deletion region.