Drug Research and Drug Development in the 21st Century
Science and Ethics
1st Edition
Published on 3. July 1989
Book
Paperback/Softback
XII, 310 pages
978-3-540-50961-5 (ISBN)
Description
Distinguished scientists and members of the medical
profession discuss the research and development of safe and
suitable drugs for the long-term treatment of chronic
diseases. The book provides an up-to-date survey on new
insights and technologies - as well as ethical
considerations - , since traditional means and methods of
drug research and drug development may no longer suffice to
meet the challenges of the next century.
More details
Series
Language
English
Place of publication
Berlin
Germany
Publishing group
Springer Berlin
Target group
Professional and scholarly
Research
Illustrations
14 s/w Abbildungen
XII, 310 p. 14 illus.
Dimensions
Height: 244 mm
Width: 170 mm
Thickness: 18 mm
Weight
562 gr
ISBN-13
978-3-540-50961-5 (9783540509615)
DOI
10.1007/978-3-642-74615-4
Schweitzer Classification
Other editions
Additional editions
H.P. Wolff | A. Fleckenstein | Egon O. Philipp
Drug Research and Drug Development in the 21st Century
Science and Ethics
E-Book
12/2012
Springer
€96.29
Available for download
Content
History and Philosophy of Bayer Pharmaceutical Research.- Science, Responsibility, and Society.- Opening Remarks.- Message of Greeting.- I. Unresolved Problems of Chronic Diseases.- Demographic and Epidemiologic Trends Today.- Atherosclerosis and Coronary Heart Disease.- Rheumatoid Arthritis: A Modell of Chronic Inflammation.- Alzheimer's Disease.- Obstructive Lung Disease.- Biological Approaches to Cancer Therapy.- Challenges and Obstacles hi Clinical Evaluations of Therapy.- Problems, Pitfalls, and Opportunities in Long-term Randomized Trials.- The Impact of Clinical Trials on Clinical Practice.- Panel Discussion I: Cost Effectiveness of Drug Development and Health Economics.- II. Advanced Technologies, Scientific Achievements.- Receptors and Messengers.- Low Density Lipoproteins and Hypercholesterolemia.- Leukotrienes in Airways and Blood Vessels.- Drug Design.- Opening Remarks.- Thoughts About Gene Regulation and Mammalian Development.- Protein Crystallography and Drug Design.- Applying Engineering Principles to the Design of Cellular Biology.- Analytical Pathophysiology and Biochemistry.- Opening Remarks.- Neurotransmitters in the Brain.- Mechanisms of Cancer Metastasis.- Panel Discussion II: Objectives of Basic Research and Predictive Value Preclinical Testing.- The Patient as a Subject to Medical Research.- Ethics of Drug Research and Drug Development.- The Functions of Ethical Committees.- Reduction of Risk to Patients Through Optimized Planning of Clinical Drug Development.- The Quality of Life of Hypertensive Patients in Long-term Studies.- Panel Discussion III: Who is Concerned with Patient Welfare in Research?.- Concluding Remarks.